RESUMO
The pathological potential of glial cells was recognized already by Rudolf Virchow, Santiago Ramon y Cajal and Pio Del Rio-Ortega. Many functions and roles performed by astroglia in the healthy brain determine their involvement in brain diseases; as indeed any kind of brain insult does affect astrocytes, and their performance in pathological conditions, to a very large extent, determines the survival of the brain parenchyma, the degree of damage and neurological defect. Astrocytes being in general responsible for overall brain homeostasis are involved in virtually every form of brain pathology. Here we provide an overview of recent developments in identifying the role and mechanisms of the pathological potential of astroglia.
Assuntos
Astrócitos/fisiologia , Encefalopatias/fisiopatologia , Animais , Astrócitos/ultraestrutura , Encéfalo/patologia , Encéfalo/fisiologia , Encéfalo/fisiopatologia , Encefalopatias/patologia , Espaço Extracelular/química , Junções Comunicantes/fisiologia , Gliose/fisiopatologia , Humanos , Neurônios/fisiologia , Neurotransmissores/metabolismo , Potássio/análise , Potássio/metabolismo , Ratos , Espécies Reativas de Oxigênio/metabolismo , Sinapses/fisiologiaRESUMO
Eight new species of the genus Ptilonyssus (Berl. et Troues.) (Gamasina: Rhinonyssidae) from nasal cavities of the passeriformes from territory of the former USSR are described: P. ammomani sp. n. from Ammomanus deserti (Alaudidae) collected in Turkmenistan; P. spini sp. n. from Spinus spinus (Fringillidae) of Kaliningrad district (Russia); P. ripariae sp. n. from Riparia riparia (Hirundinidae) and P. acanthopneustes sp. n. from Phylloscopus borealis (Sylviidae) collected in Tjumen district (Russia); P. pyrrhulinus sp. n. from Pyrrhula pyrrhula (Fringillidae) and P. anthi sp. n. from Anthus trivialis (Motacillidae) of Rjazan district; P. sylviicola sp. n. from Sylviae communis (Sylviidae) collected in Tatarstan; P. cyanosylviae sp. n. from Cyanosylvia svecica (Turdidae) collected from Novosibirsk district.
Assuntos
Ácaros/classificação , Aves Canoras/parasitologia , Animais , Masculino , Ácaros/anatomia & histologia , Cavidade Nasal/parasitologia , Federação Russa , Especificidade da Espécie , TurcomenistãoRESUMO
Four new species of the nasal mite family Rhinonyssidae collected in different regions of the former USSR are described: Neonyssus (Otocorinyssus) alaudae sp. n. from Alauda arvensis L. (Alaudidae, Passeriformes) from Turkmenistan; Rhinonyssus clangulae sp. n. from Clangula hyemalis (L.) (Anatidae, Anseriformes) from Yakutia; R. marilae sp. n. from Aythya marilae L. (Anatidae, Anseriformes) from the Russian Far East; Locustellonyssus sibiricus sp. n. from Locustella certhiola (Pall.) (Sylviidae, Passeriformes) from Siberia.
Assuntos
Aves/parasitologia , Ácaros/classificação , Animais , Comunidade dos Estados Independentes , Feminino , Ácaros/anatomia & histologiaRESUMO
The authors offer a new approach to dividing patients with pain at rest into groups with stage IIIa and IIIb as they think it inappropriate to base on the values of regional arterial pressure. The above differentiation is needed because there exist qualitative differences between these stages, for instance, in stage IIIb a new factor appears --ischemic edema. The results obtained can be used for more adequate definition of the notion "critical ischemia" of the legs.
Assuntos
Arteriopatias Oclusivas/fisiopatologia , Isquemia/fisiopatologia , Perna (Membro)/irrigação sanguínea , Postura/fisiologia , Arteriopatias Oclusivas/diagnóstico por imagem , Arteriosclerose Obliterante/diagnóstico por imagem , Arteriosclerose Obliterante/fisiopatologia , Doença Crônica , Edema/diagnóstico por imagem , Edema/fisiopatologia , Hemodinâmica , Humanos , Isquemia/diagnóstico por imagem , Perna (Membro)/diagnóstico por imagem , Ultrassonografia DopplerRESUMO
Upon stimulation and blockade of dopaminergic system of rats in the shuttle box the correlation between the strategy of escape behavior and functional state of dopaminergic system has been found. The modulatory effect of these systems on the mechanism of the adequate choice is suggested.
Assuntos
Comportamento de Escolha/efeitos dos fármacos , Receptores Dopaminérgicos/efeitos dos fármacos , Animais , Benserazida/farmacologia , Encéfalo/efeitos dos fármacos , Encéfalo/fisiologia , Comportamento de Escolha/fisiologia , Combinação de Medicamentos , Haloperidol/farmacologia , Levodopa/farmacologia , Masculino , Estimulação Física/métodos , Ratos , Tempo de Reação/efeitos dos fármacos , Tempo de Reação/fisiologia , Receptores Dopaminérgicos/fisiologia , Estresse Psicológico/fisiopatologiaRESUMO
The paper shows the dependence of behavioral changes provoked by corazol on individual characteristics of the animals. The rats with high activity in the ATS demonstrated the highest response to the drugs.
Assuntos
Reação de Fuga/efeitos dos fármacos , Pentilenotetrazol/farmacologia , Animais , Condicionamento Clássico/efeitos dos fármacos , Individualidade , Masculino , Estimulação Física , Ratos , Ratos WistarRESUMO
The free behaviour experiments on rats showed during the first day the tuftsin-induced (0.3 mg/kg i. p.) increment of epileptic discharge in all the structures simultaneously. Open field behaviour depended on the sequence of penicillin and tuftsin injections. The rats with tuftsin used after the epileptiformic activity has been developed showed the behaviour analogical to the penicillin-injected animals. The preventive injections of tuftsin resulted in restoration of all behavioural indications by the third day. The optimal corrective effect has been obtained with tuftsin used preventively.
Assuntos
Epilepsia/induzido quimicamente , Penicilinas , Tuftsina/farmacologia , Animais , Encéfalo/efeitos dos fármacos , Eletroencefalografia , Epilepsia/fisiopatologia , RatosRESUMO
A study was made of the influence of ablation of the entorhinal cortex on conditioned reflexes to present and trace stimuli. Ablation resulted in a long-lasting and considerable disturbance of differentiation of time macrointervals. After the operation, elaboration or restoration of the conditioned reflex to time was delayed five or six times as compared with intact animals. There was no change in the state of motor alimentary conditioned reflex to different (single or complex) present stimuli regardless of whether the ablation was performed after or before the elaboration of conditioned reflexes. Similar results were obtained in animals of different phylogenetic groups (rats and dogs).
Assuntos
Condicionamento Clássico/fisiologia , Sistema Límbico/fisiologia , Percepção do Tempo/fisiologia , Animais , Mapeamento Encefálico , Sinais (Psicologia) , Cães , Alimentos , Hipocampo/fisiologia , Memória/fisiologia , Vias Neurais/fisiologia , Ratos , TempoAssuntos
Condicionamento Clássico/fisiologia , Corpos Mamilares/fisiologia , Animais , Mapeamento Encefálico , Gatos , Condicionamento Operante/fisiologia , Sinais (Psicologia) , Aprendizagem por Discriminação/fisiologia , Memória/fisiologia , Percepção de Movimento/fisiologia , Percepção Espacial/fisiologia , Percepção do Tempo/fisiologiaAssuntos
Aves/parasitologia , Carrapatos/classificação , Animais , Feminino , Sibéria , Carrapatos/parasitologiaRESUMO
In birds of the order Ralliformes inhabiting the southwestern part of the Caspian Sea there were found four species of mites of the family Rhinonyssidae, parasites of the nasal cavity: Sternostoma fulicae Fain et Bafort and Rallinyssus caudistigmus Strandtmann in Fulica atra L., R. caspicus sp. n. in Gallinula chloropus (L.), R. gallinulae Fain in porphyrio polyocephalus (Lath.).
Assuntos
Aves/parasitologia , Ácaros/classificação , Animais , Azerbaijão , Feminino , Ácaros/anatomia & histologiaRESUMO
A study was carried out of the variability of mited colledted from 6 species of birds as follows: Larus argentatus Pontopp., L. minutus Pall., Gelochelidon nilotica Gm., Chlidonias leucoptera (Temm.), Ch. nigra (L.) and Sterna hirundo L. Structural peculiarities characteristic of the parasites of the above species have been revealed. The mites from St. hirundo were isolated into a distinct species, Larinyssus substerna sp. n., which is most close to L. sterna Fain, 1972. The new species differs from L. sterna in a smaller size of gnathosoma and chelicerae, lesser number of hypostomal setae and the presence of pigidial shields.