RESUMO
We present a case of lichenoid secondary syphilis in the genital area in the absence of other cutaneous or systemic manifestations. The patient did not experience an eruption on the palmar or plantar surfaces, which is rare. This case also is unique because of the intense pruritus associated with the genital lesions, a remarkable dissimilarity from typical secondary syphilitic eruptions that tend to be asymptomatic.
Assuntos
Erupções Liquenoides/patologia , Penicilina G Benzatina/administração & dosagem , Sífilis , Treponema/isolamento & purificação , Adulto , Antibacterianos/administração & dosagem , Biópsia/métodos , Humanos , Masculino , Prurido/diagnóstico , Escroto , Pele/patologia , Sífilis/tratamento farmacológico , Sífilis/patologia , Sífilis/fisiopatologia , Resultado do TratamentoRESUMO
We describe the clinical and biochemical findings in a neonate requiring multiple blood transfusions and phototherapy for alloimmune hemolytic anemia and unconjugated hyperbilirubinemia, respectively. In this newborn, a severe photosensitivity reaction developed and laboratory testing revealed elevated serum and urine porphyrins at the time of the eruption. The cause of the transient porphyrinemia was likely multifactorial. Possible mechanisms include poor hepatic metabolism and reticulocyte hemolysis. However, the exact pathogenesis remains unclear at this time.
