RESUMO
ABSTRACT: New 3D-ring CZT systems with low- and medium-energy-range detectors allow for simultaneous dual-isotope lung scintigraphy. We compared 10-, 7-, 5-, and 3-minute acquisitions for 99m Tc and 81m Kr performed simultaneously on StarGuide CZT-SPECT/CT and reframed in 50 patients. Ventilation/perfusion mismatches were calculated (mean, 15.6% ± 28%), and Spearman correlation coefficients of mismatches were 0.994, 0.994, and 0.984 between 10- and 7-, 5-, and 3-minute acquisitions, respectively. No visual difference in image quality or final diagnosis was found. 3D-ring CZT-SPECT with low and medium energy range detectors allows ultrafast dual-isotope lung scintigraphy up to 3 minutes.
Assuntos
Imagem de Perfusão do Miocárdio , Tomografia Computadorizada de Emissão de Fóton Único , Humanos , Tomografia Computadorizada de Emissão de Fóton Único/métodos , Tomografia Computadorizada por Raios X , Pulmão/diagnóstico por imagem , Tomografia Computadorizada com Tomografia Computadorizada de Emissão de Fóton Único , Tecnécio Tc 99m Sestamibi , Imagem de Perfusão do Miocárdio/métodosRESUMO
ABSTRACT: Lipomatous hypertrophy of the interatrial septum is a rare lesion of the heart. CT and cardiac MR are often sufficient to determine the benign lipomatous nature of the tumor and can avoid the need for histological confirmation. Lipomatous hypertrophy of the interatrial septum contains variable amounts of brown adipose tissue, resulting in different degrees of 18 F-FDG uptake in PET. We report the case of a patient with an interatrial lesion suspected of malignancy, discovered on CT and failing cardiac MR, with initial 18 F-FDG uptake. Final characterization was made thanks to 18 F-FDG PET with ß-blocker premedication, avoiding an invasive procedure.
Assuntos
Septo Interatrial , Neoplasias Cardíacas , Lipoma , Humanos , Fluordesoxiglucose F18 , Propranolol , Hipertrofia , Septo Interatrial/patologia , Lipoma/diagnóstico por imagem , Neoplasias Cardíacas/patologiaAssuntos
Imagem de Perfusão do Miocárdio , Tomografia Computadorizada de Emissão de Fóton Único , Humanos , Tomografia Computadorizada de Emissão de Fóton Único/métodos , Coração/diagnóstico por imagem , Radioisótopos , Tomografia por Emissão de Pósitrons , Telúrio , Cádmio , Imagem de Perfusão do Miocárdio/métodosRESUMO
ABSTRACT: Statin-associated muscle symptoms are a frequent adverse effect of statin treatment and can lead to a statin-associated myopathy characterized by a significant serum creatine kinase increase. We report the case of an 80-year-old man who presented an increased muscular 18 F-FDG uptake in a statin-associated muscle symptom without creatine kinase abnormality or inflammation. Statin treatment was discontinued for 6 hours, 3 days, and 7 days on consecutive follow-up examinations. The 1-week window clearly enhanced image quality. This case illustrates the possibility of diffuse muscular 18 F-FDG uptake without myositis and the need for a minimal 1-week statin discontinuation to reduce muscular uptake.
