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1.
Biomedicine (Taipei) ; 6(4): 24, 2016 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-27848115

RESUMO

Broncholithiasis is the presence of calcific material within the tracheobronchial tree. Asymptomatic patients can be managed with observation only, whereas symptomatic disease requires surgery, rigid or flexible bronchoscopic removal. Recent reports have shown that flexible bronchoscopy can be a safe and effective option for removal of loose in addition to partially imbedded broncholiths. We present a case of a 65-yearold man with chronic cough that underwent successful cryotherapy assisted bronchoscopic removal of an imbedded broncholith. We will also review current literature regarding the management broncholithiasis.

2.
Ann Am Thorac Soc ; 11(9): 1466-75, 2014 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-25422997

RESUMO

IgG4-related disease (IgG4-RD) is a recently recognized systemic disease characterized by tumefactive lesions in various organ systems. The list of organs that can be involved continues to expand, and recently computed tomography (CT) descriptions of the pulmonary lesions found in the disease have been described. The clinical symptoms are nonspecific and may include cough, dyspnea, chest pain, and fever. The appropriate clinical presentation along with elevated serum IgG4 concentrations and pathologic evidence of lymphoplasmacytic infiltrates with abundant IgG4-positive plasma cells and storiform fibrosis is consistent with the disease. Steroids are used to treat this disease in addition to immunosupressives such as cyclosporine or rituxumab for steroid refractory disease. The pulmonary manifestations and imaging features can often mimic malignancy, and as such knowledge of the diagnostic, clinicopathologic, and radiographic features of the disease is required in order to provide appropriate diagnostic workup and treatment.


Assuntos
Doenças Autoimunes/complicações , Imunoglobulina G/sangue , Pneumopatias/diagnóstico , Pneumopatias/imunologia , Doenças Autoimunes/diagnóstico , Doenças Autoimunes/tratamento farmacológico , Diagnóstico Diferencial , Diagnóstico por Imagem , Fibrose , Glucocorticoides/uso terapêutico , Humanos , Imunossupressores/uso terapêutico , Pulmão/patologia , Pneumopatias/tratamento farmacológico , Plasmócitos/patologia
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