Hiperplasia multifocal del epitelio. Reporte de nueve casos / Multifocal epithelial hyperplasia. Report of nine cases

La hiperplasia multifocal del epitelio (HME) conocida tambiéncomo hiperplasia epitelial focal, enfermedad de Heck ó hiperplasiamultifocal del epitelio por papiloma virus, se caracterizapor la aparición de lesiones múltiples en la mucosa de la cavidadbucal en población pediátrica y se asocia a la presencia del viruspapiloma humano. El objetivo de este estudio fue conocer lascaracterísticas clínico-patológicas de los casos diagnosticadosde esta enfermedad en el Servicio de Dermatología del HospitalManuel Gea González. Se revisaron los archivos de estainstitución y se seleccionaron los casos diagnosticados comoHME. Se encontraron 9 casos. La mayoría de los pacientesfueron menores de 20 años (67%) y del sexo femenino (78%),todos los casos presentaron lesiones múltiples y siempre huboparientes directos con lesiones similares. Los lugares que seafectaron con mayor frecuencia fueron: mucosa bucal, labioinferior, paladar y comisuras. La HME es una condición de lamucosa de la cavidad bucal que solamente necesita tratamientode aquellas lesiones que representan un problema cosmético óaquellas que se traumatizan secundariamente. Las demás remitiránconforme avanza la edad del paciente. Se sugiere usarel nombre de hiperplasia multifocal del epitelio pues describemejor las características clínico-patológicas y microscópicasde la enfermedad

Multifocal epithelial hyperplasia (MEH) is also known as focalepithelial hyperplasia, Heck’s disease or multifocal papillomavirus-induced epithelial hyperplasia. It is characterised by thepresence of multiple lesions in the oral mucosa of children andit has been associated with the presence of the human papillomavirus.The aim of this study was to determine the clinicopathologicalfeatures of the cases diagnosed as MEH in theService of Dermatology of the Hospital Manuel Gea González(SDHMGG). The files of the SDHMGG were reviewed and allcases diagnosed as MEH were retrieved. Nine MEH cases werefound. Most of the patients were 20 year-old or younger (67%)and females were more commonly affected (78%). All patientspresented multiple lesions and always, close relatives with similarlesions were found. Lesions were located most commonly inthe buccal mucosa, lower lip and comissures. MEH is a soft tissueintraoral condition that needs treatment solely of the traumatisedlesions or those with cosmetic problems. Remaining lesions willdisappear with the age of the patients. It is suggested that thisentity should be named multifocal epithelial hyperplasia sincethis name describes better the clinico-pathological and microscopicfeatures of the disease

Multifocal epithelial hyperplasia. Report of nine cases.

Multifocal epithelial hyperplasia (MEH) is also known as focal epithelial hyperplasia, Heck's disease or multifocal papillomavirus-induced epithelial hyperplasia. It is characterised by the presence of multiple lesions in the oral mucosa of children and it has been associated with the presence of the human papillomavirus. The aim of this study was to determine the clinico-pathological features of the cases diagnosed as MEH in the Service of Dermatology of the Hospital Manuel Gea González (SDHMGG). The files of the SDHMGG were reviewed and all cases diagnosed as MEH were retrieved. Nine MEH cases were found. Most of the patients were 20 year-old or younger (67%) and females were more commonly affected (78%). All patients presented multiple lesions and always, close relatives with similar lesions were found. Lesions were located most commonly in the buccal mucosa, lower lip and commissures. MEH is a soft tissue intraoral condition that needs treatment solely of the traumatised lesions or those with cosmetic problems. Remaining lesions will disappear with the age of the patients. It is suggested that this entity should be named multifocal epithelial hyperplasia since this name describes better the clinico-pathological and microscopic features of the disease.