[Severe dwarfism with high plasma hGH levels and no somatomedin acitvity: Laron's syndrome (author's transl)]. / Nanisme sévère avec taux sérique d'hormone de croissance élevé et activité somatomédine nulle: syndrome de Laron. A propos d'un nouveau cas.

A case of Laron type dwarfism which is reported describes a clinical picture of isolated previous deficiency in growth hormone. But serum level of this hormone is found to be high both in regard to basic value and after ornithin stimulation. The somatomedin activity of the child serum was studied by two methods: biological assay and binding assay. This activity was found to be non-existent both in regard to basic conditions and after injection of hGH corroborating the diagnosis of dwarfism of Laron type.