Applicability of machine learning algorithm to predict the therapeutic intervention success in Brazilian smokers.

Smoking cessation is an important public health policy worldwide. However, as far as we know, there is a lack of screening of variables related to the success of therapeutic intervention (STI) in Brazilian smokers by machine learning (ML) algorithms. To address this gap in the literature, we evaluated the ability of eight ML algorithms to correctly predict the STI in Brazilian smokers who were treated at a smoking cessation program in Brazil between 2006 and 2017. The dataset was composed of 12 variables and the efficacies of the algorithms were measured by accuracy, sensitivity, specificity, positive predictive value (PPV) and area under the receiver operating characteristic curve. We plotted a decision tree flowchart and also measured the odds ratio (OR) between each independent variable and the outcome, and the importance of the variable for the best model based on PPV. The mean global values for the metrics described above were, respectively, 0.675±0.028, 0.803±0.078, 0.485±0.146, 0.705±0.035 and 0.680±0.033. Supporting vector machines performed the best algorithm with a PPV of 0.726±0.031. Smoking cessation drug use was the roof of decision tree with OR of 4.42 and importance of variable of 100.00. Increase in the number of relapses also promoted a positive outcome, while higher consumption of cigarettes resulted in the opposite. In summary, the best model predicted 72.6% of positive outcomes correctly. Smoking cessation drug use and higher number of relapses contributed to quit smoking, while higher consumption of cigarettes showed the opposite effect. There are important strategies to reduce the number of smokers and increase STI by increasing services and drug treatment for smokers.

Parent-proxy perception of overweight adolescents' health-related quality of life is different according to adolescent gender and age and parent gender.

UNLABELLED: This study assessed health-related quality of life (HRQoL) reported by overweight adolescents and compared to their parent-proxy perception of HRQoL, according to adolescent gender, adolescent age, and parent gender. Patients and a total of 179 adolescents aged 10 to 18 years with excess weight were evaluated for perceived HRQoL prior to beginning a weight-loss intervention, using the Pediatric Quality of Life Inventory (PedsQL 4.0) questionnaire, estimating quality of life in the physical, emotional, social, and school domains, as well as index measures of psychosocial and overall quality of life. Parents completed the same questionnaire estimating his or her child's HRQoL. Compared to their child's self-report, parents underestimated all the domains of HRQoL except the school domain. Parents underestimated all the domains of HRQoL among boys; however, they only underestimated the physical domain among girls. Comparisons between parent-proxy perception and self-report of the adolescent according to adolescent's age revealed that parents underestimated their children's HRQoL in the younger adolescents (10 to 13 years) for all except for the school domain and underestimated only the physical domain in older adolescents (14 to 18 years). The same comparison between parent-proxy perception and their child's self-report of HRQoL according to parent gender showed that mothers underestimated HRQoL in all domains except for the school domain, while fathers only underestimated the school domain. CONCLUSION: The differences between self-report of overweight adolescent and perceptions of their parents about the HRQoL of their children are influenced by adolescent gender and age and parent gender.

Multidisciplinary therapy reduces risk factors for metabolic syndrome in obese adolescents.

This study aims to assess the effects of a 16-week multidisciplinary program of obesity treatment on the control of metabolic syndrome (MS) and dyslipidemia in obese adolescents. Eighty-six adolescents aged 10-18 years were allocated in either the intervention group (IG; n = 44) or control group (CG; n = 42). IG was submitted to a multidisciplinary intervention based on cognitive behavioral therapy that aimed to modify eating habits and exercise behavior. We analyzed, before and after the intervention period, anthropometric parameters, body composition, bone mineral density, cardiorespiratory fitness, blood pressure, glucose, insulin, and lipid profile of the subjects. MS was classified according to International Diabetes Federation (2007) and the presence of dyslipidemia according to Back et al. (Arq Bras Cardiol 85:4-36, 2005). In the beginning of the intervention, the median number (range) of risk factors for MS present was 2.0 (0.0-5.0) in the IG and 2.0 (0.0-4.0) in the CG. After the intervention, this parameter reduced significantly in the IG (1.0 (0.0-5.0); p = 0.004) while no change was observed in the CG (2.0 (0.0-4.0); p = 0.349). In addition, we observed improvements in body mass index, waist circumference, hip circumference, maximal oxygen uptake, absolute and relative body fat, systolic blood pressure, diastolic blood pressure, and total cholesterol in the IG which was not identified in the CG. Conclusio n: We suggest that a 16-week multidisciplinary intervention based on cognitive behavioral therapy was adequate to reduce risk factors for MS in obese adolescents.

Efeito do exercício físico aeróbio sobre o perfil lipídico de pacientes idosas, portadoras de Diabetes Mellitus tipo 2, atendidas em Unidade Básica de Saúde, Maringá, Estado do Paraná / Effect of aerobic physical exercise on the lipid profile in type 2 diabetic elderly women attended in a basic health unit in Maringá, Paraná State, Brazil

Este estudo tem por objetivo verificar a influência de um programa de exercícios físicos aeróbios sobre o perfil lipídico de pacientes idosas, portadoras de Diabetes Mellitus (DM) tipo 2. Foram selecionados 40 pacientes do gênero feminino com idade maior ou igual a 60 anos. A amostra foi distribuída em dois grupos de 20 pacientes cada: Grupo Treinado, que recebeu orientação nutricional e participou das sessões supervisionadas de exercício físico aeróbio, e Grupo Controle, que recebeu somente orientação nutricional. A intervenção teve a duração de 12 semanas. O protocolo de exercício foi aplicado três vezes por semana, tendo cada sessão 1 h de duração. Os dados obtidos mostraram que o protocolo desenvolvido promoveu redução significativa nos triglicerídeos séricos (pré-teste= 190 ± 76,67 e pós-teste= 125,33 ± 45,82 mg/dL, p<0,05) e no LDL-colesterol (pré-teste= 147,98 ± 29,98 e pós-teste= 122,24 ± 17,61 mg/dL, p<0,05) no Grupo Treinado. Os resultados permitiram concluir que o programa de exercícios adotado promoveu melhora no perfil lipídico de pacientes idosas portadoras de DM tipo 2, demonstrando a importância da prática de atividade física orientada em Unidades Básicas de Saúde

Risk factors in patients with type 2 diabetes mellitus.

This study was carried out to evaluate the risk factors of type 2 diabetic patients through sociodemographic data, habits of health, anthropometric and biochemist profiles, assisted at a basic public health care unit in Maringá, Paraná. Sixty-six patients, 56 women aged over than 50 years-old were interviewed. High prevalence factors for cardiovascular risk were observed, such as: overweight and obesity, hypertension, dyslipidemia, sedentariness and inadequate diet. Data suggested the need for multidisciplinary intervention programs in health care units associated to educative programs, adjusted diet intake and regular physical activity for these diabetic patients.

Risk factors in patients with type 2 diabetes mellitus / Factores de riesgo en pacientes con diabetes mellitus tipo 2 / Fatores de risco em pacientes com diabetes mellitus tipo 2

This study was carried out to evaluate the risk factors of type 2 diabetic patients through sociodemographic data, habits of health, anthropometric and biochemist profiles, assisted at a basic public health care unit in Maringá, Paraná. Sixty-six patients, 56 women aged over than 50 years-old were interviewed. High prevalence factors for cardiovascular risk were observed, such as: overweight and obesity, hypertension, dyslipidemia, sedentariness and inadequate diet. Data suggested the need for multidisciplinary intervention programs in health care units associated to educative programs, adjusted diet intake and regular physical activity for these diabetic patients.

El objetivo de este estudio fue verificar los factores de riesgo de las complicaciones de la diabetes mellitus tipo 2, por medio del levantamiento de datos sociodemográficos, hábitos de salud, perfil antropométrico y bioquímico, de pacientes diabéticos tipo 2 atendidos en una Unidad Básica de Salud en la ciudad de Maringá, Paraná. Fueron entrevistados y evaluados 66 pacientes con más de 50 años; 56 eran del sexo femenino. Se verificó una elevada presencia de factores de riesgo cardiovascular en los pacientes investigados: sobrepeso y obesidad, hipertensión, dislipidemia, sedentarismo y dieta no saludable. Los resultados indican la necesidad de la implantación de programas de intervención multidisciplinares en unidades básicas de la salud asociada a prácticas educativas, estimulando la adopción de una dieta saludable y la práctica de actividad física regular para estos pacientes.

O objetivo deste estudo foi verificar os fatores de risco das complicações do diabetes mellitus tipo 2, por meio de levantamento de dados sociodemográficos, hábitos de saúde, perfil antropométrico e bioquímico de pacientes diabéticos tipo 2, atendidos em Unidade Básica de Saúde, na cidade de Maringá, Paraná. Foram entrevistados e avaliados 66 pacientes acima de 50 anos, sendo 56 do sexo feminino. Verificou-se elevada prevalência de fatores de risco cardiovascular nos pacientes investigados: sobrepeso e obesidade, hipertensão, dislipidemia, sedentarismo e dieta não saudável. Os resultados indicam a necessidade da implantação de programas de intervenção multidisciplinares em unidades básicas de saúde, associados a práticas educativas, estimulando a adoção de dieta saudável e a prática de atividade física regular para esses pacientes.