Extended Barrier Lifetime of Partially Cracked Organic/Inorganic Multilayers for Compliant Implantable Electronics.

Flexible and soft bioelectronics display conflicting demands on miniaturization, compliance, and reliability. Here, the authors investigate the design and performance of thin encapsulation multilayers against hermeticity and mechanical integrity. Partially cracked organic/inorganic multilayer coatings are demonstrated to display surprisingly year-long hermetic lifetime under demanding mechanical and environmental loading. The thin hermetic encapsulation is grown in a single process chamber as a continuous multilayer with dyads of atomic layer deposited (ALD) Al2 O3 -TiO2 and chemical vapor deposited Parylene C films with strong interlayer adhesion. Upon tensile loading, tortuous diffusion pathways defined along channel cracks in the ALD oxide films and through tough Parylene films efficiently postpone the hermeticity failure of the partially cracked coating. The authors assessed the coating performance against prolonged exposure to biomimetic physiological conditions using coated magnesium films, platinum interdigitated electrodes, and optoelectronic devices prepared on stretchable substrates. Designed extension of the lifetime preventing direct failures reduces from over 5 years yet tolerates the lifetime of 3 years even with the presence of critical damage, while others will directly fail less than two months at 37 °C. This strategy should accelerate progress on thin hermetic packaging for miniaturized and compliant implantable electronics.

Information escaping the correlation hierarchy of the convergence field in the study of cosmological parameters.

Using fits to numerical simulations, we show that the entire hierarchy of moments quickly ceases to provide a complete description of the convergence one-point probability density function leaving the linear regime. This suggests that the full N-point correlation function hierarchy of the convergence field becomes quickly generically incomplete and a very poor cosmological probe on nonlinear scales. At the scale of unit variance, only 5% of the Fisher information content of the one-point probability density function is still contained in its hierarchy of moments, making clear that information escaping the hierarchy is a far stronger effect than information propagating to higher order moments. It follows that the constraints on cosmological parameters achievable through extraction of the entire hierarchy become suboptimal by large amounts. A simple logarithmic mapping makes the moment hierarchy well suited again for parameter extraction.