Parasites with zoonotic potential found in commercially important fish in Tamaulipas, Northeastern Mexico.

Human population is exposed to numerous parasitic ichthyozoonoses. Although Tamaulipas state (northeastern Mexico) is well known for its fishing and aquaculture industry, there are few reports of this type of zoonosis. Therefore, it is imperative to investigate whether the parasites that affect these fish may represent a zoonotic risk for the inhabitants of the area. The objective of this study was to identify molecular and/or morphologically muscle parasites of fish from coastal locations in Tamaulipas, Mexico, and assess the risk of infection for humans. Between 2017 and 2018, 764 individual fish belonging to 28 species were examined for parasites. Collected worms were processed for their identification using morphological characteristics. In addition, partial sequences of the large subunit (28S) ribosomal RNA gene were obtained from some species to corroborate their identity. Prevalence and mean intensity of all registered infections were calculated. A total of seven species of parasites were found: cestodes (Poecilancistrium caryophyllum), trematodes (Clinostomum tataxumui, Clinostomum cichlidorum), nematodes (Eustrongylides sp., Contracaecum sp.) and pentastomids (Sebekia purdieae, Sebekia sp.). Parasites infected 10 species belonging to different fish families (Ariidae, Centrarchidae, Centropomidae, Cichlidae, Eleotridae, Ictaluridae, Mugilidae and Sciaenidae). Congeneric species of parasites or related to those registered in this study have been identified as zoonotic agents in other regions of the world. Despite the low levels of infection (2.6-16.6% prevalence and 1-5.5 parasites per infected host), there is a latent risk of transmission to humans, so it is recommended to avoid eating raw or undercooked fish meat.

Fractura de cuello femoral en niños, reporte de caso clinico / Fractures of the femoral neck in children, report of case

Paciente de 10 años 2 meses de sexo femenino quien sufrió politraumatismo en accidente de tránsito al ser arrollada por automóvil en vía pública generando trauma craneoencefálico leve y fractura de cuello femoral derecho clasificación III de Delbet con desplazamiento completo, se manejó inicialmente con tracción cutánea con 3kg y posteriormente se realizó intervención quirúrgica realizando reducción cerrada y fijación percutánea exitosa. Continuó en control ambulatorio cada 3 meses con buena evolución. Se realizó retiro de material de osteosíntesis sin complicaciones. Continúa en controles por parte del servicio de Ortopedia y Traumatología periódicamente sin presencia de secuelas. Aunque poco frecuente, la fractura de cuello femoral se presenta como un traumatismo que conlleva retos para el médico tratante dados los altos índices de fracaso terapéutico, por lo que se hace necesario conocer el impacto de ésta patología en el momento en que ocurre la lesión y en el transcurso del tiempo, a fin de mejorar las opciones terapéuticas y mejorar el pronóstico de la lesión.

A 10 years and 2 months old patient of female gender who suffered multiple trauma in traffic accident when being rolled by automobile in public road generating mild traumatic brain injury and fracture of right femoral neck classification III of Delbet with complete displacement, she was initially handled with cutaneous traction with 3kg and later surgical intervention by closed reduction, successfull procedure. She continued in ambulatory control every 3 months with good evolution. Removal of osteosynthesis material was performed without complications. She continues in controls by the service of Orthopedics and Traumatology periodically without presence of sequels. Although infrequent, femoral neck fracture presents as a trauma that presents challenges for the treating physician, given the high rates of therapeutic failure, so it is necessary to know the impact of this pathology at the moment of injury and In the course of time, in order to improve therapeutic options and improve the prognosis of the lesión.

First molecular evidence of Theileria cervi infection in white-tailed deer (Odocoileus virginianus) in Mexico.

Theileria cervi is a tick-borne protozoan that infects different deer species around the world. Clinical diseases due to Theileria cervi have been reported in white-tailed deer (Odocoileus virginianus) and mule deer (Odocoileus hemionus) in the USA, however, information about this parasite has not been documented in Mexico. Here, blood samples from three white-tailed deer (Odocoileus virginianus) from a region in northeastern Mexico were analyzed by blood smear, PCR, and DNA sequencing. The results confirmed the presence of T. cervi for the first time in white-tailed deer in Mexico.

Density-dependent condition of juvenile penaeid shrimps in seagrass-dominated aquatic vegetation beds located at different distance from a tidal inlet.

Seagrasses are critical habitats for the recruitment and growth of juvenile penaeid shrimps within estuaries and coastal lagoons. The location of a seagrass bed within the lagoon can determine the value of a particular bed for shrimp populations. Consequently, differences in the abundance of shrimp can be found in seagrasses depending on their location. As shrimp density increases, density-dependent effects on biological parameters are more likely to occur. However, knowledge about density-dependent processes on shrimp populations in nursery habitats remains limited. The present investigation was undertaken to examine the effects of population density on shrimp condition in two selected seagrass beds, located at different distance from a tidal inlet, one 25 km away (distant) and the other 1 km away (nearby), in a subtropical coastal lagoon. The study was based on monthly samplings during one year in Laguna Madre (Mexico), performing a total of 36 shrimp trawls (100 m2 each one) within each seagrass bed (n = 3 trawls per bed per month for 12 months). Shrimp density was related to the proximity to the tidal inlet (higher density was consistently observed in the nearby seagrass bed), which in turn adversely affected the condition of both species studied (Penaeus aztecus and P. duorarum). In this regard, the present study provides the first evidence of density-dependent effects on shrimp condition inhabiting a nursery habitat. Both shrimp species exhibited a negative relationship between condition and shrimp density. However, this pattern differed depending on the proximity to the tidal inlet, suggesting that shrimp populations inhabiting the nearby seagrass bed are exposed to density-dependent effects on condition; whereas, such effects were not detected in the distant seagrass bed. Shrimp density within the distant seagrass bed was probably below carrying capacity, which is suggested by the better shrimp condition observed in that area of the lagoon. Intra and interspecific competition for food items is surmised to occur, predominantly within seagrass beds near the tidal inlet. However, this hypothesis needs to be tested in future studies.

Effect of Propolis, a Honeybee Product, Against a Parasite (Ligictaluridus floridanus) from Catfish (Ictalurus punctatus) Gills.

PURPOSE: The aim of this study was to evaluate the in vitro and in vivo efficacy of propolis against Ligictaluridus floridanus on Ictalurus punctatus gills. METHODS: This study used an ethanol extract of propolis at a concentration of 300 mg mL-1, with a total polyphenol concentration of 2.77 mg mL-1 as determined by chromatography. In vitro trial used propolis concentrations at 5, 30 as well as 60 mg L-1 and a 70% ethanol control group to treat naturally infected catfish. The in vivo experiment was 16 weeks in duration, consisting of seventy-two fish infected by cohabitation and subjected to one-hour baths every 72 h during the trial. RESULTS: In vitro studies showed that parasites exposed to 60 mg L-1 of propolis displayed a significant reduction (p < 0.05) in their survival time. In vivo studies confirmed the reduction of intensity and abundance of Ligictaluridus floridanus on the gills of channel catfish. CONCLUSION: This study has provided the first challenge of propolis against L. floridanus on I. punctatus gills and shows that propolis has an anthelmintic effect.

A Preliminary Study of Largemouth Bass Virus in Mexico.

Disease outbreaks and mortalities caused by largemouth bass virus (LMBV) in largemouth bass ( Micropterus salmoides) have been reported in the US. Blood and mucus samples tested by PCR to assess the presence of LMBV in largemouth bass in northeastern Mexico were negative, and further monitoring is needed.

Hematological and clinical chemistry changes induced by acute stress during handling and capture of catfish ( Ictalurus punctatus ) / Cambios hematológicos y bioquímicos provocados por estrés agudo causado por manejo y captura de bagre ( Ictalurus punctatus )

ABSTRACT Objetive . Evaluation of hematological and biochemical parameters of culture channel catfish (Ictalurus punctatus) under acute stress by management and capture practice. Materials and methods . Fish (200 g mean) were maintained in culture tanks and divided in two treatments, in duplicate, (n=15x2x2=60 fishes). Thirty catfish were exposed for 5 min to acute stress (TE) by management and capture practice, while other group not (control group, TnE). 10 fish for treatment were collected at 0, 6, and 24 h post-stress for blood collection, where TnE fishes were anesthetized along work. Complete blood count (manual method) and blood biochemical (spectrophotometry) of fish samples were evaluated and their results were analyzed using a Student's t-distribution. Results . The erythrocytes, hematocrit, hemoglobin and glucose level of TE animals was significantly higher (p<0.05) at 6 h post-stress, in comparison of TnE. Immune cells in fish TE decreased at 6 and 24 h post-stress, where leukocytes and lymphocytes were significantly lower that TnE (p<0.05) at 24 h post-stress. Other evaluated parameters did not show significant differences along this study. Conclusions . Those results suggest that several hematological and blood biochemical parameters in fish changed by acute stress generated by management and capture practice.

RESUMEN Objetivo . Evaluar los efectos del estrés agudo debido al manejo y captura sobre los parámetros hematológicos y bioquímicos en bagre de canal (Ictalurus punctatus) bajo cultivo. Materiales y métodos . Los peces (200 g promedio) fueron mantenidos en tanques de cultivo y divididos en dos tratamientos, por duplicado, (n= 15 x 2 x 2 = 60 peces). Treinta bagres fueron expuestos por 5 min a estrés agudo (TE) por manejo y captura, mientras que otro grupo no (grupo control, TnE). Diez peces de cada tratamiento fueron colectados a las 0, 6, y 24 h post-estrés para la extracción de sangre, los bagres del TnE fueron anestesiados durante su manejo y captura. Se evaluó el hemograma (método manual) y bioquímica sanguínea (espectrofotometría). Los resultados fueron analizados mediante la prueba de t student. Resultados . El contenido de eritrocitos, hematocrito, hemoglobina y glucosa de los animales TE fue significativamente mayor (p<0.05) a las 6 h post-estrés en comparación de TnE. Las células inmune en peces TE disminuyeron a las 6 y 24 h post-estrés, siendo leucocitos y linfocitos significativamente menores en el TnE (p<0.05) a las 24 h post-estrés. Otros parámetros evaluados no presentaron diferencias significativas en lo largo del estudio. Conclusiones . Los resultados sugieren que varios indicadores hematológicos y bioquímica sanguínea en los peces son alterados por el estrés agudo ocasionado por manejo y captura.

Anatomía radicular, una mirada desde la micro-cirugía endodóntica: Revisión / Root anatomy, a view from the microsurgery endodontic: Review

Resumen El conocimiento de ia anatomía radicular de cada uno de los grupos de dientes, es un aspecto importante que contribuye juntos con otros aspectos clínicos, a un mejor resultado de los procedimientos de micro-cirugía endodóntica (MCE). Variaciones anatómicas entre individuos de una misma población, suscitan para el endodoncista, una evaluación diagnóstica detallada de cada caso en particular para facilitar el abordaje quirúrgico. El objetivo de esta revisión es realizar una descripción de la anatomía radicular y del sistema de conductos radiculares de los diferentes grupos de dientes y sus variaciones anatómicas según la literatura científica disponible a la fecha, que permitirá al clínico tener una visión más amplia y detallada, que podrá aplicar para la planeación y ejecución de los procedimientos de MCE.

Knowing the root anatomy of each groups of teeth, it is an important aspect that contributes with other clinical aspects, to a better outcome of the procedures in endodontic micro-surgery(MCE). Anatomical variations between individuals of the same population, arise in the endodontist, a detailed diagnostic evaluation of each particular case, which will facilitate the surgical approach. The objective of this review is to describe the anatomy and root canal system of different groups of teeth and anatomical changes according to available scientific literature to date, allowing the clinician to have a more comprehensive and detailed vision, you can apply for the planning and execution of procedures for MCE.

Spatial Analysis of Metal Profiles in Sediments in a Tropical Estuary: A Geostatistical Approach.

The spatial structure and distribution of heavy metals [cadmium (Cd), copper (Cu), iron (Fe), lead (Pb), and nickel (Ni)] in sediments were geostatistically analyzed along the estuarine ecosystem of Tigre River-San Andres Lagoon (Tamaulipas, Mexico). In most cases, heavy-metal concentrations exhibited a strong spatial autocorrelation along the estuary as indicated by variogram analysis. Heavy-metal concentrations were found to be higher in the middle estuary, close to the mouth of the Tigre River, and declined as distance from the mouth increased. Metal mean levels at the middle estuary were 2.41 mg/kg Cd, 4.80 mg/kg Cu, 172.36 mg/kg Fe, 5.22 mg/kg Pb, and 2.10 mg/kg Ni. The spatial distribution of heavy metals suggests the existence of a common heavy-metal source located in this area of the estuary. The importance of wastewater discharges and open dumping in the town of El Moron, adjacent to the mouth of the Tigre River, is highlighted; these are believed to be the anthropogenic sources for heavy metals in this estuarine ecosystem.

Effects of Hydrogen Peroxide and Metrifonate on Monogenean ligictaluridus floridanus on Catfish ( Ictalurus punctatus , Rafinesque) Gills.

Hydrogen peroxide (H2O2) and metrifonate (Mtf) are common products used in ectoparasite infestations on fish cultures. The therapeutic efficacy of H2O2 and Mtf on a common monogenean parasite, Ligictaluridus floridanus, was evaluated in channel catfish ( Ictalurus punctatus ). In vitro trials were conducted using excised fish gills naturally infected with L. floridanus, which were immersed in H2O2 (150, 300, and 570 mg L(-1)) and Mtf (0.25, 0.5, and 0.75 mg L(-1)) solutions. The efficacy of the treatments was based on the survival time of the parasites, observed microscopically. In addition, an in vivo trial using catfish juveniles, naturally infected with L. floridanus, was also performed. One group received immersion baths of 570 mg L(-1) H2O2 (3%) during 4 min; the Mtf (90%) group received 0.5 mg L(-1) Mtf for 10 min. Treatments were done on days 3, 7, and 11 of the experiment. Results indicate that baths with Mtf do not significantly reduce the mean intensity of the parasite per gill arch, nor do they reduce the in vitro survival time of parasites during treatment; H2O2 baths at 570 mg L(-1) during 4 min were effective (P < 0.05) against adult and juvenile stages of L. floridanus. This study supports the use of H2O2 as an effective antiparasitic agent against I. punctatus .

Inpatient stroke care quality for veterans: are there differences between Veterans Affairs medical centers in the stroke belt and other areas?

BACKGROUND: Stroke mortality has been found to be much higher among residents in the stroke belt region than in the rest of United States, but it is not known whether differences exist in the quality of stroke care provided in Department of Veterans Affairs medical centers in states inside and outside this region. OBJECTIVE: We compared mortality and inpatient stroke care quality between Veterans Affairs medical centers inside and outside the stroke belt region. METHODS: Study patients were veterans hospitalized for ischemic stroke at 129 Veterans Affairs medical centers. Inpatient stroke care quality was assessed by 14 quality indicators. Multivariable logistic regression models were fit to examine differences in quality between facilities inside and outside the stroke belt, adjusting for patient characteristics and Veterans Affairs medical centers clustering effect. RESULTS: Among the 3909 patients, 28·1% received inpatient ischemic stroke care in 28 stroke belt Veterans Affairs medical centers, and 71·9% obtained care in 101 non-stroke belt Veterans Affairs medical centers. Patients cared for in stroke belt Veterans Affairs medical centers were more likely to be younger, Black, married, have a higher stroke severity, and less likely to be ambulatory pre-stroke. We found no statistically significant differences in short- and long-term post-admission mortality and inpatient care quality indicators between the patients cared for in stroke belt and non-stroke belt Veterans Affairs medical centers after risk adjustment. CONCLUSIONS: These data suggest that a stroke belt does not exist within the Veterans Affairs health care system in terms of either post-admission mortality or inpatient care quality.

Rural-urban differences in inpatient quality of care in US Veterans with ischemic stroke.

PURPOSE: Differences in stroke care quality for patients in rural and urban locations have been suggested, but whether differences exist across Veteran Administration Medical Centers (VAMCs) is unknown. This study examines whether rural-urban disparities exist in inpatient quality among veterans with acute ischemic stroke. METHODS: In this retrospective study, inpatient stroke care quality was assessed in a national sample of veterans with acute ischemic stroke using 14 quality indicators (QIs). Rural-Urban Commuting Areas codes defined each VAMC's rural-urban status. A hierarchical linear model assessed the rural-urban differences across the 14 QIs, adjusting for patient and facility characteristics, and clustering within VAMCs. FINDINGS: Among 128 VAMCs, 18 (14.1%) were classified as rural VAMCs and admitted 284 (7.3%) of the 3,889 ischemic stroke patients. Rural VAMCs had statistically significantly lower unadjusted rates on 6 QIs: Deep vein thrombosis (DVT) prophylaxis, antithrombotic at discharge, antithrombotic at day 2, lipid management, smoking cessation counseling, and National Institutes of Health Stroke Scale completion, but they had higher rates of stroke education, functional assessment, and fall risk assessment. After adjustment, differences in 2 QIs remained significant-patients treated in rural VAMCs were less likely to receive DVT prophylaxis, but more likely to have documented functional assessment. CONCLUSIONS: After adjustment for key demographic, clinical, and facility-level characteristics, there does not appear to be a systematic difference in inpatient stroke quality between rural and urban VAMCs. Future research should seek to understand the few differences in care found that could serve as targets for future quality improvement interventions.

Observation of bacterial type I pili extension and contraction under fluid flow.

Type I pili are proteinaceous tethers that mediate bacterial adhesion of uropathogenic Escherichia coli to surfaces and are thought to help bacteria resist drag forces imparted by fluid flow via uncoiling of their quaternary structure. Uncoiling and recoiling have been observed in force spectroscopy experiments, but it is not clear if and how this process occurs under fluid flow. Here we developed an assay to study the mechanical properties of pili in a parallel plate flow chamber. We show that pili extend when attached E. coli bacteria are exposed to increasing shear stresses, that pili can help bacteria move against moderate fluid flows, and characterize two dynamic regimes of this displacement. The first regime is consistent with entropic contraction as modeled by a freely jointed chain, and the second with coiling of the quaternary structure of pili. These results confirm that coiling and uncoiling happen under flow but the observed dynamics are different from those reported previously. Using these results and those from previous studies, we review the mechanical properties of pili in the context of other elastic proteins such as the byssal threads of mussels. It has been proposed that the high extensibility of pili may help recruit more pili into tension and lower the force acting on each one by damping changes in force due to fluid flow. Our analysis of the mechanical properties suggests additional functions of pili; in particular, their extensibility may reduce tension by aligning pili with the direction of flow, and the uncoiled state of pili may complement uncoiling in regulating the force of the terminal adhesin.

Does inpatient quality of care differ by age among US veterans with ischemic stroke?

BACKGROUND: Some studies have found that older individuals are not as likely as their younger counterparts to be treated with some guideline-based stroke therapies. We examined whether age-related differences in inpatient quality of care exist among US veterans with ischemic stroke. METHODS: This was a retrospective study of a national sample of veterans admitted to 129 Veterans Affairs medical centers for ischemic stroke during fiscal year 2007. Inpatient stroke care quality was examined across 14 inpatient processes of care, including dysphagia screening, National Institutes of Health Stroke Scale (NIHSS) score documentation, thrombolysis, deep venous thrombosis prophylaxis, antithrombotic therapy by hospital day 2 and at discharge, early ambulation, fall risk assessment, pressure ulcer risk assessment, rehabilitation needs assessment, atrial fibrillation management, lipid management, smoking cessation counseling, and stroke education. RESULTS: Among the 3939 veterans with ischemic stroke, the mean age was 67.8 years (standard deviation, 11.5). The overall performance rate was >70% for 10 of the 14 quality indicators. In unadjusted analyses, older patients were less likely to receive lipid management, smoking cessation, NIHSS documentation, and early ambulation compared with younger patients; conversely, older patients were more likely to receive dysphagia screening and stroke education. After adjusting for demographic, clinical, and hospital level characteristics, the age-related differences in processes of care were less consistent; however, the youngest patients were more likely to receive smoking cessation counseling and the oldest patients were less likely to receive lipid management. CONCLUSIONS: Risk-adjusted inpatient stroke care quality varies little with age for veterans admitted to a Veterans Affairs medical center for acute ischemic stroke.

Morphological variation in a secondary contact between divergent lineages of brown trout (Salmo trutta) from the Iberian Peninsula.

The aim of this study was to analyze the morphological variation of brown trout (Salmo trutta) in the Duero basin, an Atlantic river basin in the Iberian Peninsula, where a spatial segregation of two divergent lineages was previously reported, based on isozyme, microsatellite and mtDNA data. In these studies, two divergent pure regions (Pisuerga and Lower-course) and several hybrid populations between them were identified. Morphological variation was evaluated in 11 populations representative of the genetic differentiation previously observed in the Duero basin, using multivariate analysis on 12 morphometric and 4 meristic traits. A large differentiation between populations was observed (interpopulation component of variance: 41.8%), similar to that previously detected with allozymes and microsatellites. Morphometric differentiation was also reflected by the high classification success of pure and hybrid individuals to their respective populations, using multivariate discriminant functions (94.1% and 79.0%, respectively). All multivariate and clustering analyses performed demonstrated a strong differentiation between the pure regions. The hybrid populations, though showing large differentiation among them, evidenced an intermediate position between the pure samples. Head and body shape traits were the most discriminant among the morphometric characters, while pectoral rays and gillrakers were the most discriminant among the meristic traits. These results confirmed the high divergence of the brown trout from the Duero basin and suggest some traits on which selection could be acting to explain the spatial segregation observed.

Morphological variation in a secondary contact between divergent lineages of brown trout (Salmo trutta) from the Iberian Peninsula

The aim of this study was to analyze the morphological variation of brown trout (Salmo trutta) in the Duero basin, an Atlantic river basin in the Iberian Peninsula, where a spatial segregation of two divergent lineages was previously reported, based on isozyme, microsatellite and mtDNA data. In these studies, two divergent pure regions (Pisuerga and Lower-course) and several hybrid populations between them were identified. Morphological variation was evaluated in 11 populations representative of the genetic differentiation previously observed in the Duero basin, using multivariate analysis on 12 morphometric and 4 meristic traits. A large differentiation between populations was observed (interpopulation component of variance: 41.8 percent), similar to that previously detected with allozymes and microsatellites. Morphometric differentiation was also reflected by the high classification success of pure and hybrid individuals to their respective populations, using multivariate discriminant functions (94.1 percent and 79.0 percent, respectively). All multivariate and clustering analyses performed demonstrated a strong differentiation between the pure regions. The hybrid populations, though showing large differentiation among them, evidenced an intermediate position between the pure samples. Head and body shape traits were the most discriminant among the morphometric characters, while pectoral rays and gillrakers were the most discriminant among the meristic traits. These results confirmed the high divergence of the brown trout from the Duero basin and suggest some traits on which selection could be acting to explain the spatial segregation observed.

A microsatellite genetic map of the turbot (Scophthalmus maximus).

A consensus microsatellite-based linkage map of the turbot (Scophthalmus maximus) was constructed from two unrelated families. The mapping panel was derived from a gynogenetic family of 96 haploid embryos and a biparental diploid family of 85 full-sib progeny with known linkage phase. A total of 242 microsatellites were mapped in 26 linkage groups, six markers remaining unlinked. The consensus map length was 1343.2 cM, with an average distance between markers of 6.5 +/- 0.5 cM. Similar length of female and male maps was evidenced. However, the mean recombination at common intervals throughout the genome revealed significant differences between sexes, approximately 1.6 times higher in the female than in the male. The comparison of turbot microsatellite flanking sequences against the Tetraodon nigroviridis genome revealed 55 significant matches, with a mean length of 102 bp and high sequence similarity (81-100%). The comparative mapping revealed significant syntenic regions among fish species. This study represents the first linkage map in the turbot, one of the most important flatfish in European aquaculture. This map will be suitable for QTL identification of productive traits in this species and for further evolutionary studies in fish and vertebrate species.

Herpes simplex virus detection in oral mucosa lesions in patients undergoing oncologic therapy.

UNLABELLED: The presence of Herpes Simplex Virus (HSV) has been a frequent detection in gingivitis and ulcerations of oral mucosa in patients undergoing oncologic therapy. In these patients, lesions tend to show atypical clinical patterns, leading to misdiagnosis. OBJECTIVES: To detect HSV, using an ELISA test, in oral lesions of patients under oncologic therapy, to determine localization of these lesions in the oral cavity, to relate their presence with the general diagnosis of the patient and to compare the test results with the previous clinical diagnosis of the lesions. STUDY DESIGN: Thirty lesions where examined in nineteen pediatric patients under oncologic therapy. Direct samples of all lesions were taken and an ELISA test for HSV type I and II was applied to them. General diagnosis of the patients was consigned, as well as localization of the lesions in the oral cavity and clinical diagnosis of them. A database was elaborated with all the information. RESULTS: 33% of lesions were positive to the test, most of them in patients with acute myeloid leukemia. Localization of lesions was not restricted to areas of mucosa attached to periosteum, but also in areas like the dorsum of the tongue. Positive predictivity of clinical diagnosis was 56,25% and negative predictive index was 92,86%. Sensitivity of the test was 90% and specificity was 65%. CONCLUSIONS: It is very important to corroborate clinical diagnosis of gingivitis and ulcerative lesions of the oral cavity of patients under oncologic therapy with laboratory tests, because of the atypical clinical presentation that can lead to misdiagnosis.