RELACIÓN ENTRE INGESTA ALIMENTICIA Y ESTRÉS ACADÉMICO, REACCIONES FISICAS, PSICOLÓGICAS Y COMPORTAMENTALES EN ESTUDIANTES DE LA UNIVERSIDAD AUTÓNOMA DE CHIHUAHUA, MÉXICO / RELATIONSHIP BETWEEN FOOD INTAKE AND ACADEMIC STRESS, PHYSICAL, PSYCHOLOGICAL AND BEHAVIORAL REACTIONS IN STUDENTS OF THE AUTONOMOUS UNIVERSITY OF CHIHUAHUA, MÉXICO

l estrés académico puede presentarse en estudiantes sometidos a diversas exigencias y requisitos universitarios, provocando diferentes reacciones de estrés, físicas, psicológicas y comportamentales, reduciendo su calidad de vida y provocando consecuencias como: depresión, tristeza, fatiga y dolores de cabeza, afectando su estado nutricional. Se investigó la relación entre ingesta de alimentos y estrés académico en estudiantes del cuarto semestre de la Licenciatura en Medicina de la Universidad Autónoma de Chihuahua. La población de estudio, dado el carácter piloto de la investigación, se realizó mediante muestreo simple, aleatorio, sin reemplazo, con un diseño mixto, descriptivo, comparativo y transversal, utilizándose el cálculo del tamaño muestral con un intervalo de confianza de 95%, resultando N=117; 51 hombres y 66 mujeres entre 19 y 43 años de la generación 2019, a quienes se les aplicó el inventario SISCO de estrés académico. Se encontró mayor frecuencia en situaciones que provocan preocupación y nerviosismo, sobrecarga de tareas y trabajo, inquietud, problemas de concentración, fatiga crónica y apatía. Las estrategias más utilizadas fueron: desarrollo de planes y ejecución de tareas y capacidad asertiva. El 92.2% (n=108) de la población encuestada manifestó preocupación y nerviosismo, resultando 52,1% (n=61) en mujeres y 40.1% (n=47) en hombres. El 38.5% (n=45) de las mujeres entre 21 y 43 años, muestran una mayor relación entre aumentar o reducir el consumo de alimentos en correspondencia con sentimientos de depresión y tristeza. El estrés académico, suele estar relacionado con diferentes manifestaciones psicológicas, físicas y conductuales, que pueden influir directamente en la población estudiantil, afectando gravemente sus hábitos alimenticios y nutricionales

Academic stress can occur in students subjected to various university demands and requirements, causing different, causing different physical, psychological and behavioral reactions. Reducing quality of life and causing consequences such as: depression, sadness, fatigue and headaches, affecting their nutritional status. The relationship between food intake and academic stress was investigated in students in the fourth semester of the Bachelor of Medicine at the Autonomous University of Chihuahua. The study population, given the pilot nature of the research, was carried out through simple, random sampling, without replacement, with a mixed, descriptive, comparative and transversal design, using the sample size calculation with a 95% confidence interval resulting in N=117; 51 men and 66 women between the ages of 19 and 43, from the 2019 generation, to whom the SISCO inventory of academic stress was applied. A greater frequency was found in situations that cause worry and nervousness, overload of tasks and work, restlessness, concentration problems, chronic fatigue and listlessness. The most used strategies were plan development and execution of tasks and assertive ability. 92.2% (n=108) of the surveyed population expressed concern and nervousness, in 52.1% (n=61) women and 40.1% (n=47) men. The 38.5% (n=45) of women between 21 and 43 years old show a greater relationship between increasing or reducing food consumption in correspondence with feelings of depression and sadness. Academic stress is usually related to different psychological, physical and behavioral manifestations, which can directly influence the student population, seriously affecting their eating and nutritional habits

Quality of Life of Patients submitted to Total Knee Arthroplasty / Qualidade de vida de pacientes submetidos à artroplastia total do joelho

Objective: the aim of this study was to evaluate the quality of life between patients who have already undergone the TKA surgery and those who have not. Methodology: 118 patients [60 undergoing TKA (G1) and the remaining 58 awaiting the procedure (G2)] answered questions about QoL using the WOMAC and SF-36 protocols. The comparison was performed using the chi-square test and Student's t-test, with a significance level of 0.05. Results: with regard to clinical aspects, there was a higher level of pain in Group G2, as well as greater frequency in the use of medications, especially for pain relief. In the QoL evaluation, significant difference was observed in all the domains of the generic questionnaire SF-36 and in WOMAC, estando a capacidade functional do G2 reduzida e abaixo do nível observado nos pacientes do G1. Conclusion: patients with advanced knee arthrosis who underwent TKA, compared to those who did not undergo the procedure, had better quality of life in all domains assessed by both the general SF-36 questionnaire and the WOMAC questionnaire.

Objetivo: o objetivo deste estudo foi avaliar a qualidade de vida entre pacientes que já se submeteram à cirurgia de ATJ e aqueles que ainda não passaram pelo procedimento. Metodologia: 118 pacientes [60 submetidos à ATJ (G1) e os 58 restantes aguardando o procedimento (G2)] responderam perguntas sobre QV usando os protocolos WOMAC e SF-36. A comparação foi realizada usando o teste qui-quadrado e o teste t de Student, com um nível de significância de 0,05. Resultados: em relação aos aspectos clínicos, houve um maior nível de dor no Grupo G2, bem como maior frequência no uso de medicamentos, especialmente para alívio da dor. Na avaliação da QV, foi observada diferença significativa em todos os domínios do questionário genérico SF-36 e no WOMAC, estando a capacidade funcional do G2 reduzida e abaixo do nível observado nos pacientes do G1. Conclusão: pacientes com artrose avançada de joelho que se submeteram à ATJ, em comparação com aqueles que não passaram pelo procedimento, apresentaram melhor qualidade de vida em todos os domínios avaliados tanto pelo questionário geral SF-36 quanto pelo questionário WOMAC.

Recomendaciones de tratamiento y seguimiento en pacientes con amiloidosis hereditaria mediada por transtirretina / Recommendations for treatment and follow-up in patients with transthyretin-mediated hereditary amyloidosis

Resumen Introducción: La amiloidosis hereditaria mediada por transtirretina es una enfermedad autosómica dominante, con compromiso sistémico y progresivo, que altera la función de múltiples órganos, y se asocia con una alta morbilidad y mortalidad. Se presenta compromiso neurológico, cardiaco, autonómico, oftalmológico y nefrológico, entre otros, que se relacionan con el genotipo del paciente. Estas alteraciones afectan la calidad de vida y tienen una relación directa con la mortalidad temprana en estos pacientes. La neuropatía periférica es un marcador temprano de la enfermedad. Su identificación permite un tratamiento temprano con terapias modificadoras de la enfermedad, en busca de la estabilización de la progresión de la enfermedad, lo cual, acompañado de un seguimiento adecuado, tiene un impacto positivo en la calidad de vida de los pacientes y una prolongación de la expectativa de vida. Objetivo: Estructurar una serie de recomendaciones adecuadas al entorno local sobre el tratamiento y seguimiento en pacientes con amiloidosis hereditaria mediada por transtirretina. Materiales y método: Se utilizó la metodología Delphi y se estableció como punto de corte un 75% de favorabilidad. Resultados y conclusiones: Se plantearon una serie de recomendaciones basadas en la evidencia disponible y las recomendaciones internacionales, aplicables al entorno local, sobre métodos diagnósticos que faciliten la detección temprana del paciente afectado y los parámetros de inicio del tratamiento y el seguimiento que mejoren la calidad de vida, disminuyan las complicaciones y aumenten la expectativa de vida de estos pacientes.

Abstract Introducción: Transthyretin-mediated hereditary amyloidosis is an autosomal dominant disease with progressive systemic involvement that affects the function of multiple organs and is associated with high morbidity and mortality. Patients present neurological, cardiac, autonomic, ophthalmological and renal involvement, among others, related to the patient's genotype. These alterations affect quality of life and are directly related to early mortality. Peripheral neuropathy is an early marker of the disease. Its identification allows early treatment with disease-modifying therapies aimed at stabilizing disease progression, which, along with adequate follow-up, has a positive impact on patients' quality of life and prolongs life expectancy. Objective: To structure a series of recommendations appropriate to the local setting on treatment and follow-up in patients with hereditary transthyretin-mediated amyloidosis. Materials and methods: Delphi methodology was used, and a cut-off point of 75% favorability was established. Results and conclusions: A series of recommendations were presented based on the available evidence and international recommendations, applicable to the local setting, on diagnostic methods that facilitate early detection of the affected patient and the parameters for initiation of treatment and follow-up that improve the quality of life, decrease complications, and increase the life expectancy of these patients.

Case report: Serotoninergic and cholinergic syndromes induced by self-medication.

Self-medication is a part of the self-care practices carried out by the elderly in their environment. The aim of this case report is to show how the self-medication of fluoxetine and dimenhydrinate in an older adult can induce serotoninergic and cholinergic syndromes, showing symptoms such as nausea, tachycardia, tremor, loss of appetite, memory loss, decreased vision, falls, and increased urination. An older adult who has been diagnosed with arterial hypertension, dyslipidemia, diabetes mellitus, and a recent diagnosis of essential thrombosis is the subject of this case report. After the analysis of the case, cessation of fluoxetine was recommended to avoid withdrawal symptoms, therefore decreasing the need for dimenhydrinate and the medicines used for dyspepsia. After the recommendation, the patient showed an improvement in the symptoms. Finally, the comprehensive evaluation process of the medication in the Medicines Optimization Unit achieved the detection of the problem and improved the patient's health condition.

Bioinformatics Insights on the Physicochemical Properties of SCN5A Mutant Proteins Associated with the Brugada Syndrome.

BACKGROUND: The Brugada syndrome (BrS) is a heart rhythm condition that is commonly associated with a strong predisposition for sudden cardiac death. Malignant ventricular arrhythmias could occur secondary to the dysfunction of the cardiac sodium voltage-gated Na(v)1.5 channel (SCN5A). OBJECTIVE: This study aimed to perform a multiparametric computational analysis of the physicochemical properties of SCN5A mutants associated with BrS using a set of bioinformatics tools. METHODS: In-house algorithms were calibrated to calculate, in a double-blind test, the Polarity Index Method (PIM) profile and protein intrinsic disorder predisposition (PIDP) profile of each sequence, and computer programs specialized in the genomic analysis were used. RESULTS: Specific regularities in the charge/polarity and PIDP profile of the SCN5A mutant proteins enabled the re-creation of the taxonomy, allowing us to propose a bioinformatics method that takes advantage of the PIM profile to identify this group of proteins from their sequence. CONCLUSION: Bioinformatics programs could reproduce characteristic PIM and PIDP profiles of the BrS-related SCN5A mutant proteins. This information can contribute to a better understanding of these altered proteins.

Ethanolic extract of Lippia graveolens stem reduce biochemical markers in a murine model with metabolic syndrome.

Metabolic Syndrome (MetS) is a risk to develop metabolic-chronic degenerative disease, it is important to find natural alternatives to help decrease the risk. Mexican oregano has a traditional use in Mexican food, moreover, has pharmacologic effects that can help to reduce risk the metabolic syndrome. The aim of this work was to determine the effect of Mexican oregano ethanolic extract in metabolic syndrome in murine model. Ethanolic extract of Mexican oregano (Lippia graveolens) stem (Ext) had a favorable effect on biochemical markers in a murine model of MetS, induced by injection of monosodium glutamate (MSG). From newborn female mice, two groups were formed: control and the MSG groups, which received a dosage of 2 mg/kg of MSG via subcutaneous injection at the second and fourth postnatal day (PD 2,4), and 4 mg/kg at the PD 6, 8, 10 to induce obesity. On week 13, a part of the MSG group received Ext (group MSG + Ext) at 300 mg/kg, administered orally daily from week 13 to week 18. The results indicated that ethanolic extract of Lippia graveolens stem decreases the percentage of body fat, waist circumference, and body weight gain as well as cholesterol, serum triglyceride concentrations and systolic and diastolic pressure. Insulin and leptin hormone values showed a significant effect with the Ext administration. However, hepatic lipoperoxidation levels of MSG and MSG + Ext groups did not show any statistically significant differences between them, both being higher than the control group. Taking in consideration the results obtained in this study, it is concluded that the administration of Ext had a beneficial effect in the murine model with MetS. This is the first study demonstrating the potential of the polar fraction Lippia graveolens stem in MetS.

Cytotoxic activity of ethanolic extracts of Lippia graveolens HBK leaves and stem against lung cancer cell line SK-LU-1 / Actividad citotóxica de extractos etanólicos de hoja y tallos de Lippia graveolens HBK contra la línea celular de cáncer de pulmón SK-LU-1

Lippia graveolens HBK (Verbenaceae) is an aromatic herb of economic importance in Mexico, known as oregano. The leaves are used as condiments, and people use this species for respiratory and digestive disorders. The aim of this work was to evaluate the cytotoxic effect of ethanolic extracts obtained from free-oil leaves (L9) and stem (S15), against lung cancer cell line SK-LU-1, through tetrazolium salt (MTT) assay. Extracts concentrations of 0.3 to 300 µg/mL were used and HFF-1 as normal control cells. Both L9 and S15 extracts, showed cytotoxic effect, although stem was stronger than leaves and without damage to normal cell control. The phenolic compounds caffeic acid and acacetin werein higher concentration in L9, whereas naringenin, taxifolin, eriodictyol, luteolin, and apigenin had higher concentrations in S15. The ethanolic extracts of L. graveolens have excellent cytotoxic activity, and have a wide possibility of use in lung cancer treatment.

Lippia graveolens HBK. (Verbenaceae) es una hierba aromática de importancia económica en México, conocida como orégano. Las hojas se usan como condimento y en medicina tradicional se utiliza para aliviar malestares respiratorios y digestivos. El objetivo de este trabajo fue evaluar el efecto citotóxico de extractos etanólicos obtenidos de hojas sin aceite (L9) y tallo (S15), sobre la línea celular de cáncer de pulmón SK-LU-1, mediante el ensayo de la sal de tetrazolium (MTT). Los extractos se aplicaron a concentraciones de 0,3 a 300 µg/mL y se utilizaron células HFF-1 como control normal. Tanto los extractos L9 como S15 mostraron efecto citotóxico, aunque el efecto del tallo fue mayor al de las hojas y sin daño al control celular normal. Los compuestos fenólicos ácido cafeico y acacetina se encontraron en mayor concentración en L9, mientras que naringenina, taxifolina, eriodictyol, luteolina y apigenina tuvieron mayor concentración en S15. Los extractos etanólicos de L. graveolens tienen una excelente actividad citotóxica, con amplia posibilidad de utilizar en el tratamiento de cáncer de pulmón.

Assessment of sleep and stress level in individuals with chronic pain.

Introduction: The experience of living with chronic pain allows for the appearance of changes in sleep patterns, mood, and stress levels. Objective: To describe the phases of stress and the quality of sleep in patients with chronic pain. Material and Methods: Cross-sectional study carried out at the pain clinic of the HUPES Complex, Salvador-Bahia. Data collection between March 2016 and November 2017. Instruments: Sociodemographic questionnaire, Numerical Pain Scale (EVN), Mini-Sleep Questionnaire (MSQ), and Stress Symptoms Inventory for LIPP adults (ISSL). Categorical variables were expressed by absolute and relative frequency and quantitative variables by means and standard deviation (SD). The comparison of categorical variables was performed using the chi-square test. Values of p<0.05 were considered statistically significant. Results: Mean age (standard deviation) of 50.0 (10) years, 89.6% of whom were female. Predominance of people with a partner, with religion, high school, and unemployed or removed by the INSS. They have severe sleep disorders, severe pain, and the presence of stress in the resistance phase. Most subjects reveal that they have improved with the treatment and have moderate self-esteem and personal satisfaction, despite the presence of anxious and depressive symptoms. Conclusion: Chronic pain has a very significant impact on life, increasing the level of stress, compromising and limiting daily activities, and showing more presence of anxious and depressive symptoms in people who suffer from chronic pain.

Percepção da sensação subjetiva de bem-estar geral em sujeitos tratados com homeopatia: uma abordagem qualitativa / Perception of the subjective sensation of general well-being in subjects treated with homeopathy: a qualitative approach

Durante o tratamento homeopático a melhora costuma ser identificada a partir de uma sensação inespecífica de bem-estar, denominada Sensação Subjetiva de Bem-Estar Geral (SSBEG). Este estudo qualitativo buscou compreender como sujeitos tratados com homeopatia percebem a SSBEG a partir de uma compreensão hermenêutica associada à visão da Medicina Centrada na Pessoa. Foram entrevistados sujeitos que faziam acompanhamento no ambulatório de Homeopatia de uma faculdade particular em Salvador-Bahia e utilizada a análise de conteúdo para avaliação dos resultados. A SSBEG apresentou-se como um estado de equilíbrio dinâmico no qual sujeito é capaz de gerir a sua vida, lidar com seus sofrimentos, buscando novas formas de sentir-se bem. Implica um estado de satisfação, de harmonia, de equilíbrio interno, não apenas uma ausência de sofrimento, mas uma sensação de estar vivendo inteiramente.

To evalu ate response to homeopathic treatment, improvement can be referred to as an unspecific sense of well-being. This sensation is named in homeopathic literature as Subjective Sensation of General Well-Being (SSGWB). This study so ught to qualitatively analyze how subjects treated with homeopathy perceive SSGWB after at least 6 months of treatment, based on a hermeneutic approach along with a Person-Centered Medicine perspective. Semi-structured interviews were conducted with subjectswho were being followed up at the homeopathic outpatient clinic of the medical center of a private college in Salvador-Bahia and used content analysis to evaluate results. The SSGWB presented itself as a state of dynamic equilibrium in which the subject can manage his life, deal with his sufferings, looking for new ways to feel good. It implies a state of satisfaction, harmony, internal balance, not just an absence of suffering but a feeling of being fully alive.

Durante el tratamiento homeopático, la mejora generalmente se identifica a partir de una sensación de bienestar no específica llamada sensación subjetiva de bienestar general (SSBEG). Este estudio buscó comprender cómo los sujetos tratados con homeopatía perciben SSBEG, basado en una comprensión hermenéutica asociada con la visión de la Medicina Centrada en la Persona. Se entrevistó a sujetos que fueron monitoreados en la clínica ambulatorial de homeopatía de una universidad privada en Salvador-Bahía y se utilizó el análisis de contenido para evaluar los resultados. El SSBEG se presentó como un estado de equilibrio dinámico, en el que el sujeto es capaz de gestionar su vida, afrontar sus sufrimientos, buscar nuevas formas de sentirse bien. Implica un estado de satisfacción, armonía, equilibrio interior, no solo una ausencia de sufrimiento, sino una sensación de estar viviendo con plenitud.

Impairment of quality of life due to anxiety and depression in patients with chronic pain / Comprometimento da qualidade de vida por ansiedade e depressão em pacientes com dor crônica

ABSTRACT BACKGROUND AND OBJECTIVES: Chronic pain causes functional and social disability, resulting in emotional impact. This study's objective was to describe the main impairments of activities of daily living, anxious and depressive symptoms, and quality of life in patients with chronic pain. METHODS: Cross-sectional study with chronic pain outpatients. Analysis of clinical and sociodemographic variables, as well as activities of daily living. Assessment of pain, anxious and depressive symptoms by the Hospital Anxiety and Depression Scale, quality of life by the Medical Outcomes Study 36 - Item Short Form Health Survey questionnaire and data analysis by the SPSS statistical software. RESULTS: The study observed limitations in work, movement, leisure and home activities, quality of life below the median and worse for the physical and emotional domains. Sleep was very impaired, followed by partial difficulty with appetite and sexual activity. Although they had anxious and depressive symptoms, most participants were moderately satisfied with their treatment. CONCLUSION: Chronic pain has a very significant impact on quality of life, impairing and limiting daily activities more intensely in individuals with anxious and depressive symptoms.

RESUMO JUSTIFICATIVA E OBJETIVOS: Dor crônica acarreta incapacidade funcional e social, impactando emocionalmente os indivíduos. O objetivo deste estudo foi descrever os principais comprometimentos das atividades de vida diária, sintomas ansiosos e depressivos e qualidade de vida em pacientes com dor crônica. MÉTODOS: Estudo transversal com pacientes de ambulatório de dor crônica. Análise das variáveis clínicas e sociodemográficas, assim como das atividades de vida diária. Avaliação de dor, de sintomas ansiosos e depressivos pela Hospital Anxiety and Depression Scale, de qualidade de vida pelo questionário Medical Outcomes Study 36 - Item Short Form Health Survey e a análise dos dados no programa estatístico SPSS. RESULTADOS: Foi evidenciada limitação para o trabalho, movimento, lazer e atividade domiciliar, qualidade de vida abaixo da mediana e pior para os domínios aspectos físicos e emocionais. O sono foi muito comprometido, seguido de dificuldade parcial para apetite e atividade sexual. Embora apresentassem sintomas ansiosos e depressivos, a maioria dos participantes estavam moderadamente satisfeitos com o tratamento. CONCLUSÃO: A dor crônica impacta de forma muito significativa na qualidade de vida, comprometendo e limitando as atividades diárias de modo mais intenso nos portadores de sintomas ansiosos e depressivos.

Quality Of Life and Associated Factors in Latin American Patients Undergoing Total Hip Arthroplasty.

BACKGROUND: The objective of this study was to determine whether individuals with hip osteoarthritis who undergo THA have higher HRQOL scores than those awaiting the procedure; An additional aim was to investigate associated factors exerting an impact on HRQOL. MATERIALS AND METHODS: A cross-sectional study was conducted. Participants were divided into two groups: pre-THA and post-THA. Functional capacity was assessed using the Harris Hip Score, and HRQOL was measured using a validated and adapted version of the WOMAC questionnaire. A multivariate analysis of the WOMAC results was used to identify the main variables associated with HRQOL in both groups. RESULTS: The post-THA group had higher HRQOL scores (100.4 ± 88.5) than the pre-THA group (197.8 ± 54.1). The domains Pain (68.0 ± 19.0 versus 34.7 ± 30.8), Stiffness (61.2 ± 28.9 versus 29.9 ± 33.1), and Physical Activity (68.6 ± 16.1 versus 36.6 ± 30.2) also had higher scores in the post-THA group. Pain was the variable most frequently associated with the increase in post-THA HRQOL scores. Other variables such as occupation, time of diagnosis, joint function, and body weight also had an impact on the HRQOL of both groups. CONCLUSIONS: 1. Individuals who underwent THA had higher scores for HRQOL compared to those still awaiting the procedure. 2. Pain was the variable most strongly associated with quality of life.

Desenvolvimento de instrumento em doenças raras: acesso à saúde e ao suporte social / Development of instrument in rare diseases: access to health and social support / Desarrollo de instrumento en enfermedad raras: acceso a la salud y al apoyo social

INTRODUÇÃO: A condição crônica degenerativa relacionada às Doenças Raras (DR) é permeada por processos sociais e de acesso à saúde complexos, cuja compreensão exige avaliação na perspectiva dos acometidos. OBJETICO: Construir um instrumento que possibilite avaliar a percepção do acesso à saúde e ao suporte social destinado aos acometidos por DR. MÉTODOS: Estudo de desenvolvimento de um instrumento embasado no modelo proposto por Luiz Pasquali. RESULTADOS: Após análise fatorial, o resultado final que mostrou evidências preliminares de validação foi um instrumento com quatro domínios: Recursos de Saúde, Recursos Financeiros, Aspectos Sociais e Aspectos Individuais, com 10 itens. CONSIDERAÇÕES FINAIS: O instrumento final desenvolvido reuniu evidências de validade, revelando qualidade dos itens em representar os conceitos subjacentes a cada domínio. Por meio de suas propriedades psicométricas, o instrumento mostrou que tem representatividade no que concerne à percepção do acometido por DR quanto ao seu acesso à saúde e ao suporte social.

INTRODUCTION: The chronic degenerative condition related to Rare Diseases (DR) is permeated by complex social processes and access to health, whose understanding requires evaluation from the perspective of affected patients. OBJECTIVE: To build up an instrument that allows those affected by these pathologies to evaluate their perception regarding access to healthcare and social support. METHODS: Study on the development of an instrument based on the model proposed by Luiz Pasquali. RESULTS: After a factorial analysis, the final result that showed preliminary evidence of validation was an instrument with four domains: Health Resources, Financial Resources, Social Aspects, and Individual Aspects, with 10 items. FINAL CONSIDERATIONS: The final instrument developed gathered evidence of validity, revealing item quality in representing the concepts underlying each domain. Through its psychometric properties, the instrument showed that it has representativeness regarding the perception of the affected by DR regarding their access to health and social support..

INTRODUCCIÒN: La condición crónica degenerativa relacionada a las Enfermedades Raras (ER) está impregnada por procesos sociales y de acceso a la salud complejos, cuya comprensión exige evaluación en la perspectiva de los acometidos. OBJETIVO: Construir un instrumento que posibilite evaluar la percepción del acceso a la salud y al apoyo social destinado a los acometidos por ER. MÈTODOS: Estudio sobre el desarrollo de un instrumento en el modelo propuesto por Luiz Pasquali. RESULTADOS: Después del análisis factorial, el resultado final que mostró evidencias preliminares de validación fue un instrumento con cuatro dominios: Recursos de Salud, Recursos Financieros, Aspectos Sociales y Aspectos Individuales, con 10 ítems. CONSIDERACIONES FINALES: El instrumento final desarrollado reunió evidencia de validez, revelando la calidad del elemento al representar los conceptos subyacentes a cada dominio. A través de sus propiedades psicométricas, el instrumento demostró que tiene representatividad acerca de la percepción de los afectados por RD con respecto a su acceso a la salud y al apoyo social.

Quality of Life and Associated Factors in Latin American Patients Undergoing Total Hip Arthroplasty.

BACKGROUND: The objective of this study was to determine whether individuals with hip osteoarthritis who undergo THA have higher HRQOL scores than those awaiting the procedure; An additional aim was to investigate associated factors exerting an impact on HRQOL. MATERIALS AND METHODS: A cross-sectional study was conducted. Participants were divided into two groups: pre-THA and post-THA. Functional capacity was assessed using the Harris Hip Score, and HRQOL was measured using a validated and adapted version of the WOMAC questionnaire. A multivariate analysis of the WOMAC results was used to identify the main variables associated with HRQOL in both groups. RESULTS: The post-THA group had higher HRQOL scores (100.4 ± 88.5) than the pre-THA group (197.8 ± 54.1). The domains Pain (68.0 ± 19.0 versus 34.7 ± 30.8), Stiffness (61.2 ± 28.9 versus 29.9 ± 33.1), and Phy-sical Act--vity (68.6 ± 16.1 versus 36.6 ± 30.2) also had higher scores in the post-THA group. Pain was the variable most frequently associated with the increase in post-THA HRQOL scores. Other variables such as occupation, time of diagnosis, joint function, and body weight also had an impact on the HRQOL of both groups. CONCLUSIONS: 1. Individuals who had undergone THA showed higher HRQOL scores in all domains when compared to those still awaiting the procedure, and pain reduction was the variable most strongly associated with the improvement in quality of life of those patients. 2. Occupation and mobility were associated with the Stiffness domain of QOL; Occupation also had a bearing on health-related quality of life as a whole. 3. Physical Activity of the WOMAC instrument was associated with time of diagnosis, patient's body weight, and function as assessed by the HHS.

Percepção de cuidadores quanto aos riscos de acidentes na infância / Perception of caregivers as to the risk of accidents in childhood

Objetivo: compreender como cuidadores de crianças menores de dez anos percebem os riscos de acidentes no ambiente doméstico. Metodologia: estudo do tipo transversal. Foram entrevistados 60 (sessenta) responsáveis por alunos de uma escola pública municipal. A coleta de dados ocorreu em dezembro de 2014 e de julho a outubro de 2015. Resultados: quanto à amostra houve a prevalência de mulheres entre 18 e 40 anos de idade, com companheiro e ensino médio. A maior parte relatou não trabalhar e possuir renda média familiar de até 1 salário mínimo. A percepção geral dos entrevistados foi a de que a queda é o acidente não letal mais comum e o acidente automobilístico é o que causa mais mortes de crianças no país. Afirmaram ainda que os maiores riscos em casa são a queda seguida da queimadura, mas apenas uma pequena parcela acreditava que os riscos são passíveis de prevenção. Conclusão: acidentes com crianças em casa ainda são subestimados e pouco valorizados pelos adultos. Assim é fundamental que esforços sejam empreendidos para conscientizar os cuidadores quanto ao tema e a necessidade do seu comprometimento para que haja uma efetiva redução desses índices no país.

Objective: to understand how carers of children under ten perceive the risks of accidents in the domestic environment. Methodology: cross-sectional study. Were interviewed 60 (sixty) responsible by students of a municipal public school. The data were collected during the periods of December 2014 and from July to October 2015. Results: as for the sample, there was a prevalence of women between 18 and 40 years of age, with partner and high school. Most reported not working and owning average family income of up to 1 minimum wage. The general perception of the interviewees was that the fall is the most common non-fatal accident and the automobile accident is what causes the most child deaths in the country. They also said that the biggest risks at home are the fall followed by the burn, but only a small portion believed that the risks are preventable. Conclusion: accidents with children at home are still underestimated and undervalued by adults. Thus, it is fundamental that efforts be made to educate caregivers about the theme and the need for their commitment so that there is an effective reduction of these indices in the country

Redes alimentarias alternativas de Medellín y el Oriente de Antioquia: espacios de construcción de confianza / Alternative Food Networks in Medellin and Eastern Antioquia: Building Spaces of Trust

Antecedentes: el abastecimiento de alimentos en las ciudades es mayoritariamente dirigido por empresas transnacionales; usa circuitos largos, estimula el uso de agroquímicos en la producción de alimentos y con frecuencia no genera precios justos. Estas características han llevado a la construcción de un sector alternativo que articule nuevos mecanismos de producción, distribución y consumo de alimentos. Objetivo: describir las principales características de las redes alimentarias alternativas de Medellín y la subregión Oriente del departamento de Antioquia, sus actores, procesos y relacionamiento entre productores, distribuidores y consumidores. Materiales y métodos: estudio cualitativo de casos colectivos; se entrevistaron personas relacionadas con 15 redes alimentarias alternativas, se realizaron entrevistas semiestructuradas, observación participante en espacios de distribución y no participante en zonas de producción. Resultados: se halló en estas iniciativas el cimiento de un sistema alimentario alternativo, fundamentado en la agroecología, el comercio justo y el consumo saludable. Al ser analizadas desde los constructos teóricos del capital social, se halló que estas redes trabajan por tender puentes entre productores y consumidores y reforzar lazos entre los primeros eslabones del sistema; sin embargo, un posicionamiento más fuerte requiere fortalecer la asociatividad. Conclusiones: el naciente sector alternativo representa una oportunidad para consolidar sistemas alimentarios que contribuyan a generar capital social como bien público colectivo

Background: Food supply in cities is largely managed by multinational companies using widespread systems, promoting the use of agrochemicals in food production, and generating unfair pricing and access. These factors have led to the creation of an alternative sector highlighting new mechanisms of production, distribution, and consumption of foods. Objective: Describe the principle characteristics of alternative food networks in Medellin and the eastern sub-region of the state of Antioquia, highlighting the actors, processes, and relationships among producers, distributors, and consumers of said food products. Materials and Methods: Qualitative collective case study in which the participants were selected for interviews given their ties to 15 alternative food networks and systems. Semi-structured interviews were conducted, as well as active observation in distribution areas and passive observation in production zones. Results: The basis for healthy food systems was found in these alternative initiatives, which are based on agro-ecology, fair trade, and healthy consumption and consumerism. When analyzed from the theoretical constructs of social capital, it's seen that these networks help build ties between producers and consumers, and reinforce the bonds between the first links of these systems; however, stronger positioning is needed to strengthen these association. Conclusions: The recent advent of alternative food systems represents an opportunity to consolidate food sectors that contribute to the generation of social capital for the collective good of the population.

[Organic food consumption: is it possible to develop public policy? A case study of Medellín]. / Los consumidores de alimentos orgánicos, ¿es posible construir política pública?

INTRODUCTION: Introduction: in several countries, there is an increasing trend of consumers and distributors of organic food. Objective: to identify consumer motivation, a socioeconomic profile and possible sociopolitical actions for the development of public policy by the consumers of organic products supplied by 12 alternative food distribution networks in Medellín and Eastern Antioquia. Methods: qualitative study with semi-structured interviews and participant and non-participant observation. Results: the main reason for organic food consumption is personal wellbeing, specifically health, followed by care for the environment and social welfare because such consumption contributes to improving the quality of life of poor producers (farmers and indigenous people). The consumption of these foods is also in some cases a form of resistance against the food industry, agroindustry and supermarkets; however, this social awareness does not imply that consumers commit themselves to sociopolitical actions transcending to the collective sphere. Conclusion: action by local governments is required to develop strategies that consolidate the transformative potential of consumer practices regarding organic products from alternative food networks.

INTRODUCCIÓN: Introducción: el incremento de consumidores y distribuidores de alimentos y productos orgánicos constituye una tendencia en varios países. Objetivo: establecer las motivaciones para el consumo, el perfil socioeconómico y las posibles acciones de carácter sociopolítico para la construcción de políticas públicas realizadas por los consumidores de productos orgánicos de las 12 redes de distribución alternativa de alimentos que existen en Medellín y el oriente antioqueño. Métodos: estudio cualitativo con entrevistas semiestructuradas y observación participante y no participante. Resultados: se halló que la principal razón de consumo es el bienestar individual, específicamente la salud, seguido del cuidado del medio ambiente y el bienestar social porque se contribuye a mejorar la calidad de vida de los productores pobres (campesinos e indígenas). Se encontró, además, que el consumo de estos alimentos, se hace en algunos casos como forma de resistencia frente a la industria de alimentos, la agroindustria y los supermercados. Sin embargo, esta conciencia social no implica que los consumidores se comprometan con acciones sociopolíticas para trascender a la esfera colectiva. Conclusión: se requiere una acción de los gobiernos locales para desarrollar estrategias que consoliden el potencial transformador de las prácticas de los consumidores de productos orgánicos de las redes alternativas de alimentos.

Qualidade de vida e funcionalidade nos pacientes com desordens do manguito rotador / Quality of life and functionality in patients with rotator cuff disorders

OBJETIVO: Verificar se existe correlação entre os domínios da qualidade de vida e a funcionalidade nos pacientes com desordens do manguito rotador. MÉTODO: Estudo do tipo transversal com 109 pacientes avaliados entre outubro 2013 e fevereiro 2014. Para avaliar a qualidade de vida foi utilizado o questionário WORC, e as escalas UCLA e ASES para avaliação da funcionalidade. RESULTADO: Amostra de 73 mulheres e 36 homens (média de idade: 52,3 anos+12,8). O ombro avaliado foi o direito em 63 pacientes (57,8%). O WORC apresentou correlação positiva alta com as escalas UCLA (r= 0,73) e ASES (r= 0,77). Ao analisar o WORC verificou-se correlação mais forte com a UCLA no domínio "Trabalho" (r=0,74), e menor no domínio "Esporte/Recreação" (r= 0,67). Quando comparado o WORC com a ASES identificou-se a maior correlação com o domínio "Trabalho" (r= 0,79) e menor correlação com o domínio "Emoções" (r= 0,64). CONCLUSÃO: Alterações na funcionalidade, frequentes nestas desordens, impactam na qualidade de vida em especial no domínio "Trabalho".

OBJECTIVE: To evaluate the correlation between different domains of quality of life and functionality in patients with rotator cuff disorders. METHODS: Cross sectional study with 109 patients evaluated between October 2013 and February 2014. The WORC questionnaire was used to evaluate quality of life, and the UCLA and ASES scales to evaluate functionality. RESULTS: The sample included 73 female and 36 males (mean age 52,3+12,8 years). The right shoulder was evaluated in 63 patients (57,8%). There was a high positive correlation between the WORC results and the UCLA (r= 0,73) and ASES (r= 0,77) scales. There was a stronger correlation between the WORC and the UCLA in the "Work" domain (r= 0,74), and a weaker correlation in the "Sport/Recreation" domain (r= 0,67). When comparing the WORC with the ASES scale, a higher correlation was identified with the "Work" domain (r=0,79) and a lower correlation with the "Emotions" domain (r= 0,64). CONCLUSION: Alterations in functionality, frequent in RCD, have a considerable impact in the quality of life in special to the "Work" domain.

Use of Adsorbent Biochar from Pequi (Caryocar Brasiliense) Husks for the Removal of Commercial Formulation of Glyphosate from Aqueous Media

Abstract This study evaluated the capacity of adsorbent biochar derived from pequi husks to remove glyphosate (commercial formulation) in aqueous medium under three pH conditions (5.5, 7.0 and 8.0). This biochar presented a mean yield of 33.1% ± 2.66% and a high amount of surface particles of small dimensions endowing it with high surface area. The results showed that removal is proportional to pH increase in the range of 5.5 to 8.0. Adsorption assays performed at pH 7 and 8 fitted better to the Langmuir pseudo-first order kinetics model with fast adsorption in the first 15 to 30 minutes. The results for the acidic pH range fit none of the adopted models satisfactorily. The results obtained suggest that adsorbent can be used as an efficient and inexpensive alternative for the adsorption of glyphosate present in commercial formulations from aqueous matrices.