[Gangrenous juvenile vasculitis of the scrotum. Report of 2 cases]. / Vasculitis gangrenosa juvenil del escroto. Aportación de dos casos.

Among the various necrotic-ulcerous processes that may become established in the genitalia, one peculiar form of scrotal gangrene was described in 1973 by Piñol et al. under the name of juvenile gangrenous vasculitis of the scrotum. The clinical and pathological features of this entity, of undetermined etiology, allows it to be singled out and differentiated from other pictures of genital ulceration. With the contribution of two new cases, which we have had the opportunity to see recently, we want to call attention towards this distinctive though uncommonly diagnosed entity. Also, to emphasize the good response of the process to appropriate antibiotic and topical treatment in a picture which, due to its initial evolutive nature, to our judgement deserves to be considered within the acute symptomatic complex of the scrotum.

[Adrenal myelolipoma]. / Mielolipoma suprarrenal.

Exposition of one case of suprarenal myelolipoma, a very rare non-functioning primitive tumour commonly diagnosed prior to surgery. Discussion of the disease's better known aspects.

[Acute scrotum as clinical presentation form of testicular tumor]. / Escroto agudo como forma de presentación clínica de un tumor de testículo.

Testis tumours usually emerge in young patients as a painless increase in the testis size accidentally noticed by the patient. Contribution of one case of non-seminomatous testis tumour which presented clinically as an acute scrotum. An exhaustive appraisal of the clinical data allowed to choose the most appropriate approach for the patient in an emergency situation.

[Inverted papilloma of the urethra]. / Papiloma invertido de uretra.

The inverted papilloma of the urethra is an exceptional entity. It occurs as a smooth surface, sessile tumour located in the prostatic urethra. Microscopically, it is lined with transitional epithelium which is projected inside the tumour, creating strands of cells with normal characteristics. All cases reported up to now have occurred in men aged between 49 and 79. None of the cases had additional urothelial injuries associated. Contribution of a new case of inverted papilloma of the prostatic urethra in a 52-year old male. Transurethral resection of the tumour was the procedure chosen. Evolution was good and no relapse nor further urothelial injuries were observed at the controls carried out over an 8-year follow-up period.

[Bladder endometriosis]. / Endometriosis vesical.

Endometriosis is the ectopic location of the endometrium. It is quite unusual to find endometrium foci within the vesical cavity, this experience representing only 1-2% of all possible locations. This paper contributes one vesical endometriosis in a 35 year old woman endoscopically diagnosed because of a solid tumour with surface bluish bullae or cysts. We used Gestrima, in dosage of 2.5 mg twice weekly, as adjuvant treatment to endoscopic surgery with complete objective response.

[Superficial carcinoma of the bladder. The pT1 G3 tumor: progression, recurrence, and survival. Treatment]. / Carcinoma superficial de vejiga. El tumor pT1 G3: progresión, recidiva y supervivencia. Tratamiento.

Surface vesical cancer continues to be a problem awaiting to be solved and with an alarmingly increasing incidence. The present report examines the inclusion criteria for the different categories as related to the accepted systems (NMT, Jwet-Marshall) and outlines the significance of the lamina propria invasion in the prognosis of patients with surface tumours. Also, it explores the various reported systems to define histological degree attending to morphological criteria. A review of prognostic factors with an emphasis on the relevance of the presence of in situ carcinoma associated to vesical tumour is included. There is an specific study of pT1 G3 tumours behaviour as related to progression, tendency to recurrence and survival; review of the different therapy approaches; and presentation of our personal experience based on the review of 448 tumours, which were compared to the results reported by the other national (Algaba, Vicente Rodríguez) and international (Heney, Soloway, Cooper, Kakizoe, etc.), authors.

[Preoperative estimate of the weight of prostatic adenoma using abdominal echography]. / Estimación preoperatoria del peso de adenoma de próstata por ecografía abdominal.

Using a sample of 41 patients, diagnosed with prostate adenoma, an estimate was made on the degree of correlation between the weight of the adenoma as predicted through abdominal ultrasound scan (x) and the actual weight after surgical removal (y). An experimental principle or mathematical formula has been worked out to translate that correlation and it allows the urologist to appraise the adenoma's actual weight as related to the ultrasound scan weight. The degree of correlation between the ultrasound-estimated weight and the actual weight was high (0.85) and statistically significant (p < 0.01). The experimental principle of mathematical formula which will allow the urologist to make a closer approximation to the actual weight of adenomas studied by ultrasound was y = 0.93 * x + 4.7.

[Results of treatment with interferon and vinblastine in renal cancer]. / Resultados del tratamiento con interferón y vinblastina en el cáncer de riñón.

Contribution of our experience with Alpha-2a Interferon and Vinblastine, for the treatment of advanced renal cancer in patients formerly not treated with nephrectomy. Pathoanatomical diagnosis was confirmed by puncture biopsy. None of the 4 patients recruited in the protocol showed objective response. In 2 patients no change was observed and in the other 2 the disease progressed. In surviving patients it was impossible to sustain therapy for more than three months. Treatment was discontinued as a result of the Interferon side-effects, such as fever, myalgia, asthenia and neuritis.

[Non-chromaffin non-functioning aortosympathetic paraganglioma]. / Paraganglioma aortosimpático nocromafín afuncionante.

The paraganglia system is the largest component in the construction of the Disseminated Neuroendocrine System, comprising cells derived from the neural crest, with ability to synthesize and secrete catecholamines, hormones and peptides. A general explanation on the subject with a personal contribution is made.