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J Med Entomol ; 57(6): 1992-1996, 2020 11 13.
Artigo em Inglês | MEDLINE | ID: mdl-32484559

RESUMO

Aedes aegypti (L.) is the primary vector of Zika, dengue, yellow fever, and chikungunya viruses. Insecticides used in mosquito control can help prevent the spread of vector-borne diseases. However, it is essential to determine insecticide resistance (IR) status before control measures are undertaken. Only the most effective insecticides should be used to avoid ineffective control and/or promotion of IR. Pyrethroids and organophosphates are the most commonly used insecticides for mosquito control. Here, the efficacy of two active ingredients (AIs; permethrin [pyrethroid], chlorpyrifos [organophosphate]), two formulated products (FPs; Biomist [AI: permethrin]) and (Mosquitomist [AI: chlorpyrifos]), and three synergists (piperonyl butoxide, diethyl maleate, S-S-S-tributyl phosphorotrithioate) was evaluated in two Ae. aegypti colonies (pyrethroid resistant and susceptible). Mosquitomist was most effective against the pyrethroid-resistant colony (100% mortality at diagnostic time). Pre-exposure to synergists did not increase the efficacy of AIs against the pyrethroid-resistant colony. Further research is needed to discover how synergists may affect the efficacy of insecticides when used on pyrethroid-resistant mosquitoes.


Assuntos
Aedes/efeitos dos fármacos , Resistência a Inseticidas , Inseticidas/farmacologia , Maleatos/farmacologia , Organotiofosfatos/farmacologia , Sinergistas de Praguicidas/farmacologia , Butóxido de Piperonila/farmacologia , Aedes/fisiologia , Animais , Clorpirifos/farmacologia , Feminino , Longevidade , Permetrina/farmacologia
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