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Br J Radiol ; 80(956): 593-602, 2007 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-17621606

RESUMO

Recent advances in molecular genetics and immunocytochemistry have clarified the cell of origin in many renal disorders. Several renal disorders are thought to involve specific segments of the nephron. Renin-secreting tumours arise from juxtaglomerular cells. Clear cell and papillary renal cell carcinoma (RCC) recapitulate the epithelium of the proximal tubules. Oncocytoma and chromophobe RCC differentiate towards Type A and Type B intercalated cells of the cortical collecting duct, respectively. Medullary collecting ducts are the target sites for the development of autosomal recessive polycystic kidney disease, collecting duct carcinoma and medullary carcinoma. Renal papillae are susceptible to unique changes such as necrosis or papillitis. The purpose of our article is threefold: to illustrate the imaging findings of renal disorders that show segmental involvement of the nephron, to describe proximal and distal nephron disorders and to correlate imaging findings of some entities with histopathological features.


Assuntos
Nefropatias/patologia , Néfrons/patologia , Carcinoma de Células Renais/diagnóstico por imagem , Carcinoma de Células Renais/patologia , Humanos , Nefropatias/diagnóstico por imagem , Glomérulos Renais/patologia , Neoplasias Renais/diagnóstico por imagem , Neoplasias Renais/patologia , Túbulos Renais/patologia , Imageamento por Ressonância Magnética , Néfrons/diagnóstico por imagem , Tomografia Computadorizada por Raios X , Ultrassonografia
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