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1.
Chaos ; 26(3): 033101, 2016 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-27036179

RESUMO

In this paper, we investigate the dynamic properties of an overlapping generations' model with capital accumulation, in which agents work in both periods of life. We compare three different expectation mechanisms: perfect foresight, myopic foresight, and adaptive expectations, focusing, in particular, on this last one. We show that the steady state is the same under each mechanism, and we prove its global stability for perfectly foresighted agents. After investigating local stability conditions under myopic expectations, we study in detail the case of adaptive expectations. We show that, under both reduced rationality mechanisms, if the share of time devoted to labor in the second period of life is large enough, periodic and complex dynamics can occur. Moreover, deepening the investigation through numerical simulations, we study the global stability behavior under adaptive expectations. Such complex scenarios also include the coexistence between the stable steady state and a periodic or chaotic attractor, giving rise to multistability, which does not arise under myopic expectations. Finally, we provide some considerations about the possibility for the agents to improve their forecasts by observing the forecasting error time series.

2.
Sci STKE ; 2007(378): pl1, 2007 Mar 20.
Artigo em Inglês | MEDLINE | ID: mdl-17374853

RESUMO

The ability of eukaryotic cells to navigate along spatial gradients of extracellular guidance cues is crucial for embryonic development, tissue regeneration, and cancer progression. One proposed model for chemotaxis is a phosphoinositide-based phase separation process, which takes place at the plasma membrane upon chemoattractant stimulation and triggers directional motility of eukaryotic cells. Here, we make available virtual-cell software that allows the execution and spatiotemporal analysis of in silico chemotaxis experiments, in which the user can control physical and chemical parameters as well as the number and position of chemoattractant sources.


Assuntos
Quimiotaxia/fisiologia , Simulação por Computador , Células Eucarióticas/fisiologia , Modelos Biológicos , Software , Membrana Celular/fisiologia , Fatores Quimiotáticos/farmacologia , Quimiotaxia/efeitos dos fármacos , Sistemas Computacionais , Citosol/fisiologia , Apresentação de Dados , Células Eucarióticas/efeitos dos fármacos , Lipídeos de Membrana/fisiologia , Proteínas de Membrana/fisiologia , Microcomputadores , Concentração Osmolar , Fosfatidilinositóis/fisiologia , Processos Estocásticos
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