[Aminotransferase and dehydrogenase activity in human brain tumours]. / Aminotransferaznaia i degidrogenaznaia aktivnost' v opukholiakh golovnogo mozga cheloveka.

Asparate and alanine aminotransferase activity is approximately the same in different lobes of cerebral hemispheres of people with an uninjured central nervous system. The maximal activity of lactate, malate and succinate dehydrogenase is in the temporal lobes and thalami, the minimal one is in the corpus callosum. The activity of aminotransferases in the brain tumour lowers: in the dedifferentiated tumour the asparate aminotransferase shows a 23-24% decrease; in the case of the meningeal sarcoma it is 2.5 times as low: the activity of alaine aminogransferase is almost 10 times as low. The activity of malate dehydrogenase decreases in the neuroectodermal tumours and sharply (almost twice) in multiform glioblastoma. In the dedifferentiated meningiomas the activity of all the dehydrogenases is increased.

[Visceral pathology in severe cranio-cerebral injuries and its pathogenetic mechanisms]. / Vistseral'naia patologiia pri tiazheloi cherepno-mozgovoi travme i ee patogeneticheskie mekhanizmy.

Pathological conditions of the internal organs and their innervation apparatus, including the limbic cortex, reticular formation, vegetative nuclei of the vagus nerves and spinal cord, peripheral ganglia, and intramural plexuses, in severe craniocerebral trauma were studied by the clinico-physiological, clinico-morphological, and neurohistological methods. The innervation apparatuses of the organs were also studied in experiments with a purposeful effect exerted on the hypothalamus. Peculiarities in the manifestation of visceral pathology in diencephalic and mesencephalobulbar forms of brain lesions were established. Histological changes in the tissues of the organs and in the structures forming the efferent and afferent links of the visceral reflex arc are described. The dependence of the structural disturbances in the central and peripheral components of the vegetative nervous system on hypothalamic affection was confirmed experimentally. Their dynamics was studied. The data of the investigations are discussed from the standpoint of the results of a complex of purposeful surgical and nonoperative treatment of craniocerebral trauma and its complications. Particular attention is focussed on the role of the neuro-conduction mechanism in the development of pathological conditions of the organs. The tissue changes are considered to be neurodystrophic.