RESUMO
OBJECTIVE: Fine Needle Aspiration Cytology (FNAC) is a rapid, reliable and safe diagnostic tool used for various lesions of the oral cavity and salivary glands. The present study was undertaken to categorize the cytomorphology of the oral cavity and salivary gland lesions on FNAC and to assess the accuracy of FNAC in arriving at a diagnosis. MATERIALS AND METHODS: A prospective study on oral cavity swellings and salivary gland aspirates was done during a 2 year period from August 2015 to July 2017 in which a total of 70 FNAC's were performed. There were 12 aspirates obtained from oral cavity swellings and 58 aspirates were obtained from salivary glands. Histopathological evaluation of 65 lesions was done and was considered as gold standard. Only the lesions undergoing histopathological confirmation were included in the study. The sensitivity, specificity, diagnostic accuracy and clinical utility index were evaluated for accuracy of FNAC. RESULTS: Hard palate (33.33%) was the predominantly aspirated site in the oral cavity. Parotid gland was the predominant gland aspirated (60.32%) among the involved salivary glands. Non-neoplastic lesions constituted 18.47% cases whereas neoplastic lesions were 81.53% (60.00% benign and 21.53% malignant). Pleomorphic adenoma (28.65%) was the most common benign lesion in the oral cavity involving hard palate and as salivary gland neoplasm (70.54%). Squamous cell carcinoma (60%) was the most common malignant lesion of oral cavity involving the tongue and buccal mucosa and adenoid cystic carcinoma (44.45%) was the commonest malignancy in salivary gland malignant neoplasms. The overall sensitivity, specificity and accuracy of FNAC in the present study were 89.5%, 100% and 85% respectively. CONCLUSION: FNAC is a safe, cost-effective and reliable technique effective in diagnosing the spectrum of different lesions in the oral and maxillofacial region.
RESUMO
Filariasis presenting as multiple subcutaneous nodules is very rare and only a very few cases are reported in the literature. Microfilaria bancrofti is known to occur in different sites like breast, thyroid, lymph nodes, liver, lungs and body fluids, however, in contrast to the other filarial species, its occurrence in soft tissues is rarely reported. Conventional method of diagnosis of filariasis is by demonstration of microfilaria in peripheral blood smear which may be diurnal or nocturnal. The various species are differentiated by the morphological features like presence or absence of sheath, granules and nuclear arrangement in the tail end. We hereby report an unusual case of Wuchereria bancrofti infestation diagnosed on biopsy of subcutaneous nodule in a patient whose initial clinical presentation was of urticarial rashes over the upper extremities. In differential diagnosis of various subcutaneous nodular masses the possibility of filarial granuloma must be kept and a careful search should be done for adult worm or microfilaria in the serial tissue sections.
