Comparison of the safety and efficacy between minimally invasive cardiac surgery and median sternotomy in a low-risk mixed Asian population in Singapore.

Introduction: Minimally invasive cardiac surgery (MICS) has attracted increasing attention, with institutions increasingly adopting this approach over conventional median sternotomy (MS). This study aimed to describe the outcomes of minimally invasive cardiac surgery in our institution as the only centre with an established MICS programme in Singapore. Methods: Patients who had undergone cardiac procedures such as heart valve replacement or repair, coronary artery bypass grafting or atrial septal defect repair were included in the study. We analysed 4063 patients who had undergone MS and 390 patients who had undergone MICS between January 2009 and February 2020. Results: Over the years, the number of MICS procedures performed increased, along with an increase in MICS operations with two or more concomitant cardiac procedures and a decrease in postoperative length of stay. Compared with patients who underwent MS, those who underwent MICS had shorter length of postoperative hospital stay (P < 0.001). On multivariate analysis, patients who underwent MICS had lower rates of atrial fibrillation (P = 0.021), reoperation (P = 0.028) and prolonged ventilation (P < 0.001). However, the rates of other postoperative complications were comparable between patients who underwent MICS and those who underwent MS. Conclusion: In our institution, MICS is a safe, reproducible and efficacious technique that yields superior outcomes compared with conventional MS procedures, in some aspects. The results of this study provide further evidence and support towards adopting the minimally invasive approach to cardiac surgery in a carefully selected group of cardiac patients in Singapore.

Minimally invasive tricuspid valve surgery and concomitant MAZE procedure with closure of LA appendage through an ASD.

Utilization of the ASD as a gateway to reach the left heart in tricuspid valve surgery may facilitate the use of a mini right thoracotomy and single atriotomy approach, avoiding the need for bi-atrial incisions and/or median sternotomy.

Feasibility of transapical cardioscopic surgery in a pig model.

BACKGROUND AND AIM: We introduced a cardioscopic surgical platform for a wide range of cardiac procedures, to address various intracardiac pathologies, through the left ventricular (LV) apex on the arrested heart. The method involves endoscopic access into the LV cavity; hence the term "transapical cardioscopic surgery (TACS)." METHODS: For this proof-of-concept study, we obtained transapical access to the left ventricle in five pigs. A right minithoracotomy was used for cannulation and cardiopulmonary bypass A purse string-secured incision at the apex allows for introduction of a self-made intracavitary expander, 5 mm steerable-tip endoscopic camera as well as 5 and 3 mm endoscopic instruments. RESULTS: The trans-apical approach provided a good exposure and an adequate surgical field, which allowed us to perform mitral valve repair, mitral valve replacement, and aortic valve replacement. This approach also enabled excellent access and visualization for atrial ablation and intra-aortic procedures. All animals were rewarmed and weaned off bypass. CONCLUSIONS: The proposed transapical cardioscopic platform is feasible for major intra-cardiac procedures.

Is continuation of antiplatelets until coronary artery bypass safe in Asians?

BACKGROUND: Controversies have arisen about the risks of discontinuing antiplatelets prior to coronary artery bypass grafting. METHODS: We retrospectively studied the effects of different strategies of antiplatelet discontinuation prior to coronary artery bypass on perioperative bleeding and major adverse cardiovascular events in Asian patients in a single center in Singapore. RESULTS: 402 patients were divided into 4 groups: group A had no antiplatelets before surgery; antiplatelets were stopped for 5-7 days in group B; 2-4 days in group C; and 0-1 day in group D. Compared to group B, group D had longer intensive care unit stays and more intraoperative transfusions of blood (p = 0.006) and blood products (p < 0.05). The 1-year major adverse cardiovascular event rate was higher in groups A and D (p = 0.027). Stopping antiplatelets within 24 h of surgery was one of multiple independent predictors of intraoperative transfusion but not the 1-year major adverse cardiovascular event rate. Patients on aspirin alone had less intraoperative transfusion of platelets and postoperative minor bleeding than those on combined therapy. CONCLUSION: Continuation of antiplatelets until 2 days before coronary artery bypass in Asian patients in our institution is unlikely to increase the risks of bleeding and perioperative transfusion. Taking antiplatelets within 24 h of surgery seems to be associated with a higher rate of 1-year major adverse cardiovascular events and bleeding, and an increased risk of blood product transfusion. Thirty-day and 1-year major adverse cardiovascular event rates were higher in patients without antiplatelet treatment.

Sutureless aortic valve implantation: first experience in Asia.

Age-related degenerative calcification is currently the most common cause of aortic stenosis (AS) in adults and the most frequent reason for aortic valve replacement in patients with AS. With the increased life expectancy, a large proportion of elderly patients with AS is undergoing cardiac surgery, although many are not offered conventional aortic valve replacement due to the risks involved. However, sutureless aortic valve replacement provides an alternative for this group of elderly patients. This case series reports the first experience in Asia of sutureless aortic valve implantation in seven patients at our institution.

Irreducible dislocation of the fourth metatarsophalangeal joint--a case report.

Traumatic dislocation of the metatarsophalangeal joint of an isolated lesser toe is an uncommon injury. We report a patient who presented 1 day after a dorsiflexion injury of the right foot. Physical examination showed a shortened and angulated right fourth toe resulting in scissoring of his digits. X-rays of the right foot confirmed complete dislocation of the fourth metatarsophalangeal joint. After failing 4 attempts at closed reduction, an orthopedic consult was made, and he underwent surgery. Six months after the operation, he developed avascular necrosis of the fourth metatarsal head. Reduction of the metatarsophalangeal of an isolated lesser toe is difficult due to the anatomical constraints imposed by the surrounding soft tissue. Failure at reduction after a single attempt by an experienced emergency physician should prompt the need for an orthopedic consult in view of likely surgery required. Avascular necrosis of the metatarsal head can also occur as a late complication after such injury.

A commentary on delayed presentation of breast cancer in Singapore.

Breast cancer is the most common cancer in Singaporean women and the rate of increase in incidence is one of the highest in the world. In view of the significant contribution of delayed presentation to the disease burden in South East Asia, we reviewed the incidence of late presentation of breast cancer and the contributing factors in Singapore. Disease presentation was analysed using studies based on the Singapore Cancer Registry 2004-2008 and with data from women with breast cancer at the National University Hospital (NUH) in Singapore 1990-2007. Available literature from Singapore on factors contributing to delayed presentation was reviewed and presented here. The overall age-standardized 5-year relative survival for Singaporean women was 70% with only half diagnosed with localized cancer. Of all women diagnosed at NUH close to 20% presented at Stages III and IV. Given the magnitude of the problem of women presenting with more advanced stages of breast cancer, the National University of Singapore has joined a collaborative team with the University of Leeds (UK), the University of Malaya, and University of UAE to set up the UK-SEA-ME Psychosocial-Cultural Cancer Research Network to better understand late presentation.

Carotid artery stenosis: does the world wide web provide sufficient information to these patients?

As the use of the Internet is at its highest at present, it is reasonable to assume that patients suffering from carotid artery stenosis and its complications may use this as a potential source of information prior to hospital attendance. The relevant Web sites were initially identified and the quality of information therein was assessed independently by two assessors on the author panel. We also tested whether established Web site scoring systems (HON and DISCERN score) could predict the quality of information included on the medical Web sites. The overall quality of relevant information for these patients was found to be poor. The Spearman rank correlation between the two scoring systems was /0.64 (95% confidence interval [CI] 0.53-0.74, p < .0001). There was a good correlation between the assessors' scores for each scoring system, with a Spearman rank correlation for the DISCERN score of 0.99 (95% CI 0.99-0.99, p < .0001) and for the HON score of 0.98 (95% CI 0.97-0.98, p < .0001). We also found a good correlation between these scores and guidelines set by the assessors. Available scoring systems provide a good means of assessment. However, significant improvement is required to enhance the overall quality of health-related Web sites.