RESUMO
Streptomycin-imprinted silica microspheres were prepared by combining a surface molecular-imprinting technique with the sol-gel method. A mixture of tetrahydrofuran, ethanol, and water (6:1:1, v/v/v) was selected as dispersing solvent while 3-aminopropyltriethoxysilane and triethoxyphenylsilane acted as functional monomers, and tetraethyl orthosilicate as a cross-linker. Characterization of the molecularly imprinted polymers was conducted using scanning electron microscope and dynamic binding experiments. As compared to the nonimprinted polymers, the imprinted polymers exhibited a higher degree of saturated adsorption volume up to 26.3 mg/g, and better selectivity even in an aqueous solution with interfering compounds, including dihydrostreptomycin, neomycin, and tetracycline. The adsorption ability and selectivity were observed to be influenced by the mole ratio of 3-aminopropyltriethoxysilane and triethoxyphenylsilane. Feasibility of the polymers to be used for actual application was also evaluated with spiked samples, indicating great potential for large-scale applications. Moreover, the streptomycin-imprinted polymers can be repeatedly used for 12 cycles without losing original performance, which is beneficial for commercial use.
Assuntos
Antibacterianos/química , Polímeros/química , Estreptomicina/química , Poluentes Químicos da Água/química , Adsorção , Antibacterianos/isolamento & purificação , Microesferas , Impressão Molecular , Polímeros/síntese química , Dióxido de Silício/química , Estreptomicina/isolamento & purificação , Poluentes Químicos da Água/isolamento & purificaçãoRESUMO
Biocompatibility has always been the focal point in the study of biomaterials applied to medical apparatus. But at present, the standard system hasn't formed completely to evaluate the biomaterials. In recent years scientists tend to use general standard of evaluation. In this article, based on the recalcification time, the adhesion of platelets as well as the total quantity of plasma protein and some other evidences, combining with the Analytic hierarchy process (AHP), the method of general evaluation on the biocompatibility of anticoagulant biomaterials was discussed.
Assuntos
Humanos , Anticoagulantes , Materiais Biocompatíveis , Padrões de Referência , Proteínas Sanguíneas , Teste de Materiais , Métodos , Padrões de Referência , Adesividade PlaquetáriaRESUMO
Good anticoagulant biomaterials need good surface chemical properties, good mechanics performances and particularly good characteristics of biocompatibility, including tissue compatibility and hemocompatibility. In order to understand with greater clearness the anticoagulant biomaterial, we have to characterize them by different methods. In this paper, the approaches to assessing and displaying the characteristics of anticoagulant biomaterial are reviewed in three aspects, namely the surface chemical properties and structure, the mechanics performances the and the biocompatibility of anticoagulant biomaterial.
Assuntos
Humanos , Anticoagulantes , Materiais Biocompatíveis , Química , Coagulação Sanguínea , Teste de Materiais , Próteses e Implantes , Desenho de Prótese , Propriedades de SuperfícieRESUMO
The treatment of stained teeth has been one of the striking aspects of stomatology and esthetic dentistry. Based on detailed data and references, this article introduces the types of stained teeth and the main treatment methods including strong point, weakness, limitation of the usage, result, and the relevant mechanisms. It addresses the researches on problems in the treatment of stained teeth. Also in this paper is envisaged what will be done to treat the stained teeth in future.
Assuntos
Humanos , Facetas Dentárias , Clareamento Dental , Descoloração de Dente , TerapêuticaRESUMO
As a means to substitute the function of kidney, hemodialysis therapy has been applied to clinical therapy. The bio-compatibility of dialyser, which is the key of part of artificial kidney, is a determining factor for the therapy. This paper describes dialyser and the methods of improving bio-compatibility of dialyser.