Assuntos
Albuminas 2S de Plantas/imunologia , Antígenos de Plantas/imunologia , Arachis/imunologia , Basófilos/imunologia , Glicoproteínas/imunologia , Hipersensibilidade a Amendoim/diagnóstico , Extratos Vegetais/imunologia , Teste de Degranulação de Basófilos , Células Cultivadas , Seguimentos , Humanos , Tolerância Imunológica , Imunização , Diester Fosfórico Hidrolases/metabolismo , Valor Preditivo dos Testes , Prognóstico , Pirofosfatases/metabolismo , Tetraspanina 30/metabolismoRESUMO
We report a 69-year-old adult case with a monoclonal gammopathy incidentally discovered, associated with a moderate thrombocytopenia of 90 G/L. Study of blood smear revealed the presence of tumor cells presenting Auer rod-like inclusions, although there were not blast cells. Blood cytology as well as immunophenotyping allowed us to make the diagnosis of malignant hemopathy.
Assuntos
Carcinoma Hepatocelular/diagnóstico , Corpos de Inclusão/patologia , Leucócitos/patologia , Neoplasias Hepáticas/diagnóstico , Paraproteinemias/patologia , Idoso , Carcinoma Hepatocelular/complicações , Carcinoma Hepatocelular/patologia , Diagnóstico Diferencial , Humanos , Cirrose Hepática/complicações , Cirrose Hepática/patologia , Neoplasias Hepáticas/complicações , Neoplasias Hepáticas/patologia , Masculino , Paraproteinemias/complicações , Paraproteinemias/diagnóstico , Trombocitopenia/complicações , Trombocitopenia/patologiaRESUMO
BACKGROUND: The case of a central nervous system human herpes virus type 6 (HHV-6) and Toxoplasma gondii co-infection after an umbilical cord blood transplantation in a chronic myelomonocytic leukaemia patient is reported. CASE REPORT: A 65-year-old Caucasian man underwent an umbilical cord blood transplantation within the context of chronic myelomonocytic leukaemia. On day 37 post-graft, he presented with a severe headache; PCRs of cerebrospinal fluid and blood were positive for T. gondii and HHV-6. The patient was treated with pyrimethamine and sulfadiazine associated with ganciclovir. CONCLUSION: HHV-6 reactivation can trigger a reactivation of T. gondii. This case suggests that patients who are seropositive for T. gondii and who present with HHV-6 reactivation should be monitored closely for toxoplasmosis.