[Microbiological diagnosis and antibacterial therapy of non spore-forming anaerobic infections in emergencies]. / Mikrobiologicheskaia diagnostika i antibakterial'naia terapiia nesporoobrazuiushchikh anaérobnykh infektsii pri neotlozhnykh sostoianiiakh.

A total of 240 patients with soft tissue and wound suppurations, peritonitis, and suspected sepsis were examined. Anaerobic isolates were more frequently obtained in 20-75% of patients infections associated with facultative microbes. The use of non-culture media (bacterioscopy and gas-liquid chromatography) increased the detection rate of anaerobic infection up to 82% as compared with bacteriological diagnosis (63%). The findings and the data of monitoring of suppuration agents for several years allowed the authors to work out effective combined treatment regimes for early mixed aerobic and anaerobic infections in 80-100% of patients.

[Microbiologic diagnosis of mixed anaerobic and aerobic surgical infections]. / Mikrobiologicheskaia diagnostika smeshannykh anaérobno-aérobnykh infektsii v khirurgii.

One hundred and twelve patients with purulent affections of the abdominal and thoracic cavities as well as soft tissues and 49 patients with suspected generalization of the infection were examined. It was shown that the position of mixed anaerobic and aerobic infections in various groups of the patients could reach 70-80 per cent while the species composition of the pathogens was close to that of the normal microflora in the affected organ or its region. Bacteroides spp. played the main role in the development of anaerobic sepsis and conditioned a distinctive process. There was observed synergism of Escherichia coli and Staphylococcus spp. and they were shown to serve as indicators of the anaerobic infection due to these species in definite biotops. The use of GLC markedly lowered the time required for diagnosis of anaerobic infections which provided rational chemotherapy at the early stages of the disease with an account of the data on monitoring of the suppuration causative agent.

[Dynamic omento-pancreatostomy in the treatment of acute destructive pancreatitis]. / Dinamicheskaia omentopankreatostomiia v lechenii ostrogo destruktivnogo pankreatita.

The authors suggest a new method for treating acute pancreatitis, which is based on the principles of an "opened abdomen" but combines practically all its advantages. The operation is called "dynamic omentopancreatostomy". This method was used in 1986-87 for the treatment of 13 patients, 7 of them had destructive pancreatitis with total and subtotal necrosis of the pancreas. Severe specific complications characteristic of acute pancreatitis occurred in all of the patients. Three patients died in the post-operative period. Most of the developing complications were easily arrested by means of this new operative method. It is concluded that seriously ill patients with omentopancreonecrosis may be treated successfully by the operation of "dynamic omentopancreatostomy".

[Characteristics of the blood supply of suppurative wounds treated by a defocused beam of a CO2 laser]. / Osobennosti krovosnabzheniia gnoinykh ran, obrabotannykh rasfokusirovannym luchom CO2-lazera.

In examination of 57 patients with the use of a method of complex polarography, by oxygen and hydrogen, the increase in volumetrical rate of blood flow and oxygen tension in the purulent wounds treated by a defocused beam of the CO2 laser was established. This contributed to more favourable course of the wound process and accelerated healing. Complex polarography can be used as a diagnostic method in the purulent surgery.

[Blood microcirculation and angiogenesis in wound healing by first and second intentions]. / Mikrogemotsirkuliatsiia i angiogenez pri zazhivlenii ran pervichnym i vtorichnym natiazheniem.

Local reaction of the microvascular bed and angiogenesis of closed and infected open wounds have been studied in 72 rats. Selective contrasting of the functioning microvessels was achieved by means of intravenous injection of peroxidases, as tracers. The dynamics of microcirculatory disorders and the periods of capillary circulation recovery in the wound within 1-20 days after the injury were described. The principal resemblance of the alterations of the microvascular bed in closed and infected open wounds was established.

[Microcirculation and angiogenesis during the healing of experimental purulent wounds exposed to a defocussed CO2 laser beam]. / Osobennosti mikrotsirkuliatsii i angiogeneza pri zazhivlenii éksperimental'nykh gnoinykh ran, obrabotannykh rasfokusirovannym luchom uglekislotnogo lazera.

In experiments on rats, the state of microcirculation in purulent wounds that had been exposed to a defocussed beam from a CO2 laser is described and compared to that in similar but nonexposed wounds. The laser treatment was found to accelerate the normalization of blood supply to the wound walls; the stimulatory effect was maximal when the thermal damage to the tissues was minimal.

Laser surgery for soft tissue purulent diseases.

The original techniques of soft-tissue purulent lesion treatment by means of a continuous-wave CO2 laser are elaborated. The following laser treatment advantages--minimal tissue damage, prophylaxis of local dissemination of infection, haemostatic and sterilizing effects--have been proved experimentally. Laser utilization in clinical trial (360 cases) made it possible to obtain significantly improved outcomes and marked shortening of treatment.

[The carbon dioxide laser in the complex treatment of acute suppurative lactation mastitis]. / Uglekislotnyi lazer v kompleksnom lechenii ostrogo gnoinogo laktatsionnogo mastita.

The use of the carbon dioxide laser in the complex treatment of acute purulent lactation mastitis has substantially improved results and shortened the terms of a duration of the treatment.