Leveraging Historical Medical Records as a Proxy via Multimodal Modeling and Visualization to Enrich Medical Diagnostic Learning.

Simulation-based Medical Education (SBME) has been developed as a cost-effective means of enhancing the diagnostic skills of novice physicians and interns, thereby mitigating the need for resource-intensive mentor-apprentice training. However, feedback provided in most SBME is often directed towards improving the operational proficiency of learners, rather than providing summative medical diagnoses that result from experience and time. Additionally, the multimodal nature of medical data during diagnosis poses significant challenges for interns and novice physicians, including the tendency to overlook or over-rely on data from certain modalities, and difficulties in comprehending potential associations between modalities. To address these challenges, we present DiagnosisAssistant, a visual analytics system that leverages historical medical records as a proxy for multimodal modeling and visualization to enhance the learning experience of interns and novice physicians. The system employs elaborately designed visualizations to explore different modality data, offer diagnostic interpretive hints based on the constructed model, and enable comparative analyses of specific patients. Our approach is validated through two case studies and expert interviews, demonstrating its effectiveness in enhancing medical training.

ShortcutLens: A Visual Analytics Approach for Exploring Shortcuts in Natural Language Understanding Dataset.

Benchmark datasets play an important role in evaluating Natural Language Understanding (NLU) models. However, shortcuts-unwanted biases in the benchmark datasets-can damage the effectiveness of benchmark datasets in revealing models' real capabilities. Since shortcuts vary in coverage, productivity, and semantic meaning, it is challenging for NLU experts to systematically understand and avoid them when creating benchmark datasets. In this paper, we develop a visual analytics system, ShortcutLens, to help NLU experts explore shortcuts in NLU benchmark datasets. The system allows users to conduct multi-level exploration of shortcuts. Specifically, Statistics View helps users grasp the statistics such as coverage and productivity of shortcuts in the benchmark dataset. Template View employs hierarchical and interpretable templates to summarize different types of shortcuts. Instance View allows users to check the corresponding instances covered by the shortcuts. We conduct case studies and expert interviews to evaluate the effectiveness and usability of the system. The results demonstrate that ShortcutLens supports users in gaining a better understanding of benchmark dataset issues through shortcuts, inspiring them to create challenging and pertinent benchmark datasets.

Polyphony: an Interactive Transfer Learning Framework for Single-Cell Data Analysis.

Reference-based cell-type annotation can significantly reduce time and effort in single-cell analysis by transferring labels from a previously-annotated dataset to a new dataset. However, label transfer by end-to-end computational methods is challenging due to the entanglement of technical (e.g., from different sequencing batches or techniques) and biological (e.g., from different cellular microenvironments) variations, only the first of which must be removed. To address this issue, we propose Polyphony, an interactive transfer learning (ITL) framework, to complement biologists' knowledge with advanced computational methods. Polyphony is motivated and guided by domain experts' needs for a controllable, interactive, and algorithm-assisted annotation process, identified through interviews with seven biologists. We introduce anchors, i.e., analogous cell populations across datasets, as a paradigm to explain the computational process and collect user feedback for model improvement. We further design a set of visualizations and interactions to empower users to add, delete, or modify anchors, resulting in refined cell type annotations. The effectiveness of this approach is demonstrated through quantitative experiments, two hypothetical use cases, and interviews with two biologists. The results show that our anchor-based ITL method takes advantage of both human and machine intelligence in annotating massive single-cell datasets.

In Defence of Visual Analytics Systems: Replies to Critics.

The last decade has witnessed many visual analytics (VA) systems that make successful applications to wide-ranging domains like urban analytics and explainable AI. However, their research rigor and contributions have been extensively challenged within the visualization community. We come in defence of VA systems by contributing two interview studies for gathering critics and responses to those criticisms. First, we interview 24 researchers to collect criticisms the review comments on their VA work. Through an iterative coding and refinement process, the interview feedback is summarized into a list of 36 common criticisms. Second, we interview 17 researchers to validate our list and collect their responses, thereby discussing implications for defending and improving the scientific values and rigor of VA systems. We highlight that the presented knowledge is deep, extensive, but also imperfect, provocative, and controversial, and thus recommend reading with an inclusive and critical eye. We hope our work can provide thoughts and foundations for conducting VA research and spark discussions to promote the research field forward more rigorously and vibrantly.

VBridge: Connecting the Dots Between Features and Data to Explain Healthcare Models.

Machine learning (ML) is increasingly applied to Electronic Health Records (EHRs) to solve clinical prediction tasks. Although many ML models perform promisingly, issues with model transparency and interpretability limit their adoption in clinical practice. Directly using existing explainable ML techniques in clinical settings can be challenging. Through literature surveys and collaborations with six clinicians with an average of 17 years of clinical experience, we identified three key challenges, including clinicians' unfamiliarity with ML features, lack of contextual information, and the need for cohort-level evidence. Following an iterative design process, we further designed and developed VBridge, a visual analytics tool that seamlessly incorporates ML explanations into clinicians' decision-making workflow. The system includes a novel hierarchical display of contribution-based feature explanations and enriched interactions that connect the dots between ML features, explanations, and data. We demonstrated the effectiveness of VBridge through two case studies and expert interviews with four clinicians, showing that visually associating model explanations with patients' situational records can help clinicians better interpret and use model predictions when making clinician decisions. We further derived a list of design implications for developing future explainable ML tools to support clinical decision-making.

DECE: Decision Explorer with Counterfactual Explanations for Machine Learning Models.

With machine learning models being increasingly applied to various decision-making scenarios, people have spent growing efforts to make machine learning models more transparent and explainable. Among various explanation techniques, counterfactual explanations have the advantages of being human-friendly and actionable-a counterfactual explanation tells the user how to gain the desired prediction with minimal changes to the input. Besides, counterfactual explanations can also serve as efficient probes to the models' decisions. In this work, we exploit the potential of counterfactual explanations to understand and explore the behavior of machine learning models. We design DECE, an interactive visualization system that helps understand and explore a model's decisions on individual instances and data subsets, supporting users ranging from decision-subjects to model developers. DECE supports exploratory analysis of model decisions by combining the strengths of counterfactual explanations at instance- and subgroup-levels. We also introduce a set of interactions that enable users to customize the generation of counterfactual explanations to find more actionable ones that can suit their needs. Through three use cases and an expert interview, we demonstrate the effectiveness of DECE in supporting decision exploration tasks and instance explanations.

ProtoSteer: Steering Deep Sequence Model with Prototypes.

Recently we have witnessed growing adoption of deep sequence models (e.g. LSTMs) in many application domains, including predictive health care, natural language processing, and log analysis. However, the intricate working mechanism of these models confines their accessibility to the domain experts. Their black-box nature also makes it a challenging task to incorporate domain-specific knowledge of the experts into the model. In ProtoSteer (Prototype Steering), we tackle the challenge of directly involving the domain experts to steer a deep sequence model without relying on model developers as intermediaries. Our approach originates in case-based reasoning, which imitates the common human problem-solving process of consulting past experiences to solve new problems. We utilize ProSeNet (Prototype Sequence Network), which learns a small set of exemplar cases (i.e., prototypes) from historical data. In ProtoSteer they serve both as an efficient visual summary of the original data and explanations of model decisions. With ProtoSteer the domain experts can inspect, critique, and revise the prototypes interactively. The system then incorporates user-specified prototypes and incrementally updates the model. We conduct extensive case studies and expert interviews in application domains including sentiment analysis on texts and predictive diagnostics based on vehicle fault logs. The results demonstrate that involvements of domain users can help obtain more interpretable models with concise prototypes while retaining similar accuracy.