Acute pyelonephritis revealing a rare renal collision tumor of papillary and chromophobe cell carcinoma with sarcomatoid features.

A 59-year-old male patient was admitted to the emergency room with febrile right flank pain. The computed tomography scan and the magnetic resonance imaging had objectified lesion image occupying the upper half of the right kidney, measuring 82 mm, suggesting an infectious origin without excluding the infected tumor. He was put under antibiotics. A percutaneous biopsy revealed renal cell carcinoma with suppurative tumor necrosis. He underwent a right radical nephrectomy. The histopathological study revealed a collision tumor of papillary, chromophobe renal cell carcinoma and sarcomatoid dedifferentiation. It is the second case reported in English literature to date.

Coexistence of Emphysematous Pyelonephritis and Cystitis in a Patient with COVID-19 Complicated with Spontaneous Pneumomediastinum.

We report the first case of a 52-year-old nondiabetic male admitted for management of uremic syndrome associated with emphysematous pyelonephritis (EPN), renal and perinephric abscess, and emphysematous cystitis (EC) on a single functional kidney with a large abundance of spontaneous pneumomediastinum (SP) complicating a SARS-CoV-2 pneumonia. The patient has benefited from several dialysis sessions, intravenous antibiotics, and percutaneous drainage. His clinical course was complicated by acute respiratory distress syndrome, and unfortunately, he died nine days following admission.

Management of bilateral adrenal myelolipoma without endocrine disorder: About a rare case report.

Adrenal gland myelolipomas are benign, hormonally inactive, and mostly asymptomatic and unilateral tumors. However, it could be symptomatic and bilateral in rare cases. The diagnosis is based on a CT scan and a histological study. We present a rare case of a surgically managed bilateral adrenal gland myelolipoma with a giant mass on the left side in a 40-year-old man who presented in our department for atypical abdominal pain. The patient underwent surgical resection of the left adrenal mass. Due to the resolution of the abdominal pain, a close follow-up for the right mass by CT scan was chosen.

Spermatocytic seminoma of testis associated with undifferentiated sarcoma revealed in metastatic disease: A review and case report analysis.

Spermatocytic seminoma is a relatively rare testicular tumor and is characterized by a good prognosis. The discovery of a sarcomatous contingent modifies the prognosis of the indolent neoplasm. Only 20 cases being reported in English literature. We present the case of a 66-year-old man with a two-year history of left-sided scrotal pain and swelling. Tumor markers were normal. Ultrasound demonstrated a very large solid-cystic testicular mass. Orchidectomy was performed. Further imaging investigations revealed lung, vertebra, and retroperitoneal lymph node metastases. Histological examination and immunohistochemistry of the orchidectomy specimen concluded on spermatocytic seminoma associated with undifferentiated sarcoma component.

Kidney metastasis in a case of Merkel cell carcinoma.

Merkel cell carcinoma is a rare neuroendocrine skin tumor with a poor prognosis. Metastasis is frequent and is seen in the first few years after diagnosis. This report describes a case of renal metastasis from Merkel cell carcinoma which is an unusual clinical presentation.

Emphysematous pyelonephritis on a single anatomic kidney: About a case report and literature analysis.

Emphysematous pyelonephritis (EPN) on a single kidney is an extremely uncommon necrosing infection of renal parenchyma due often to infection by a gas-producing bacteria in a patient with uncontrolled diabetes mellitus. The management associate aggressive fluid and electrolyte resuscitation with several dialysis sessions, control of blood sugar levels, and broad-spectrum antibiotics with an urgent drainage. This paper aims to describe a case of a 68-year-old diabetic male patient who presented with EPN on a single kidney managed by conservative treatment.

A Giant Solitary Adrenal Plasmacytoma in a Patient with HIV: A Rare Case Report and Review of the Literature.

Solitary extramedullary plasmacytoma (EMP) involving the adrenal gland is an extremely rare malignancy. We report a case of a solitary adrenal plasmacytoma in an HIV-positive 50-year-old woman on antiretroviral therapy who presented with a rapidly progressing lumbar left masse. A CT scan objectified a locally advanced left adrenal mass measuring 135mm long axis. A biopsy was taken, and the histopathology with the immunohistochemical study objectified an adrenal gland plasmacytoma. The skeletal survey and the sternal suction biopsy did not show any abnormalities. The diagnosis of a solitary EMP of the adrenal gland was made. There are only 10 cases of solitary adrenal plasmacytoma with only one case associated with an HIV-positive patient reported in the literature. Therefore, this paper is aimed at presenting the second case of an HIV-positive patient diagnosed with solitary adrenal plasmacytoma.

A nasal swelling revealing a metastatic testicular extranodal NK/T-cell lymphoma: A case report and a review of literature.

Testicular ENKTCL is a rare disease. Asia is the most affected. Primary testicular NK/T-cell lymphoma is rare. Metastases are early and the prognosis is poor. Metastases mainly involve the lymph nodes, skin, contralateral testis, bone marrow, spleen and central nervous system. Nasal metastasis giving rise to bifocal presentation is extremely rare. We report the management of a patient initially seen for a nasal swelling with a hidden history of scrotal swelling, in whom nasal biopsies as well as the analysis of the orchidectomy part made it possible to retain the diagnosis of ENKTCL of the testis with a nasal metastasis.

A huge collecting duct carcinoma of the kidney in an elderly woman: Diagnosis and managment challenge (uncommon condition).

Collecting duct carcinoma, also known as Bellini duct carcinoma (BDC) is a rare type of renal tumor, arising from the distal collecting ducts. The prognosis of this disease is extremely poor due to its rapid progression with widespread metastasis. The present study reported a case of CDC involving the left renal region of a 68-year-old female patient. CT scan showed a huge mass occupying the lower portion of the left kidney. The patient underwent enlarged nephrectomy. Anatomopathological examination showed collecting duct carcinoma of the kidney. Patient's evolution was exceptionally favorable: no recurrence, no locoregional metastasis and no distant metastasis.

Fast growing papillary renal cell carcinoma in first trimester pregnancy with postoperative inferior vena cava thrombosis: A case report.

Renal cell carcinoma (RCC) is an extremely rare and fatal tumor for women of childbearing age. Consequently, the cases published in the literature are limited and medical experience with therapeutic management of newly diagnosed RCC in pregnant women is poor. We report our clinical experience with a renal tumor diagnosed in first-trimester pregnancy complicated in postoperative by an inferior vena cava thrombosis. Further reporting of such a case should help to collect more data in purpose to establish a clear, systematic and evidence guide-ligne in front of this unique situation.

Ex Vivo treatment of stones in living donor kidney by flexible ureteroscopy: Time challenge (case report).

The discovery of a kidney stone in a living kidney donor is rare. The managing technique of this situation and the timing of the treatment of the stone is not well codified. Should it be treated before the removal of the kidney or in ex-vivo after nephrectomy and in cold ischemia ? We report a case of a 60-year-old mom who donates kidney willingly to her son. The decision of the transplant team was for the removal of the left kidney (upper calyx stone of 9 mm) and the treatment of the stone in ex-vivo by flexible ureteroscopy.

Hypofertility in a persistence of mullerian duct syndrome: Case report.

INTRODUCTION: Persistent Mullerian duct syndrome is a rare form of pseudohermaphroditism, possibly resulting from the absence of Mullerian duct inhibiting factor. PRESENTATION OF CASE: We report the case of a 36 year-old patient with a syndrome of persistent Müllerian ducts (PMDS) of the female type. The Clinical examination revealed avacant scrotum, a normal penis. The spermogram analysis found azoospermia. Imaging using ultrasound and tomotensidometry found the presence of amass in the back of bladder. A Laparoscopic exploration revealed two slightly enlarged testicles, in a pelvic situation intimately confined to a rudimentary uterus with two tubes. The histological examination was in favor of a uterine endometrium and two fallopian tubes. The karyotype requested later was male 46 XY. DISCUSSION: Since the first case, between 200 and 262 cases have been reported in literature around the world, this might reveal that the incidence and prevalence of this type of diseases are not well-estimated. The diagnosis is often a fortuitous discovery during a cryptorchidism surgery or inguinal hernia, more rarely during the management of a state of infertility or the degenerescence of the testis or Mullerian derivative. It is caused by either the anti-Mullerian hormone deficiency (AMH) or a dysfunction of its receptor. CONCLUSION: A multidisciplinary approach is necessary for surgical management. long-term prognosis is favorable, though fertility seem to be decreased and also it might lead to a riskiness of malignancy owing to cryptorchidism and preserved Mullerian remants.

Penile gangrene: an unusual complication of malignant priapism in a patient with renal cell carcinoma.

A 68-year-old man presented with priapism and penile gangrene. The patient had no history of penis trauma or medications for erectile dysfunction. Corpus cavernosa aspiration cytology were positive for malignant cells. Total penectomy was performed. Enhanced chest and abdominal computed tomography showed a left renal tumor with pulmonary and hepatic metastases. Ultrasound-guided renal biopsy showed clear cell renal cell carcinoma.

Adrenal myelolipoma: from tumorigenesis to management.

Adrenal myelolipoma (MLS) is a rare, benign and non-functional neoplasm, composed of adipose tissue and myeloid. We report a rare case of adrenal myelolipoma of a 20-year-old female revealed with chronic abdominal pain. Computed tomography (CT) scan of the abdomen guided diagnosis and surgical resection was performed given symptomatic and bulky mass. Histological examination confirmed the diagnosis. At 18 months after the surgery, the patient had no evidence of recurrence. The diagnosis of MLS is radiological. Therapeutic abstention is the rule for a small, asymptomatic tumor. The surgical removal is indicated when it is bulky (exceeds 7cm), symptomatic or hormonal activity.

Complications of fat grafts growth after weight gain: report of a severe diplopia.

A 47 years old woman underwent autologous fat grafting to treat a 5×4 cm depression of the lower lid and the upper cheek secondary resection of squamous cell carcinoma and subsequent coverage by full thickness skin graft. 20 mL of autologous fat were harvested from lower abdomen, centrifuged and injected subcutaneously. The patient then gained a total of 15 kg over a period of 24 months. Eye dystopia developed while the grafted area became convex. MRI confirmed subcutaneous fat mass going to the orbital floor through the inferior septal defect. The fat excess was removed through a trans-conjonctival approach allowing for a progressive regression of diplopia after 2 months while the oedema reduced. The overall follow up from the resection-coverage and last examination was 5 years. In this case with a context of noticeable weight gain, the growth of a fat graft trapped between a sclerous plane and the eye, that penetrated the orbital cavity through a septal defect led have led to exophthalmos, ocular dystopia and diplopia. Systematic overcorrection in autologous fat grafting should be prevented, especially in functional areas and on low body mass index patient that might gain weight.

[Malignant transformation of a dermoïd cyst of the scalp. A case report]. / Dégénérescence d'un kyste dermoïde du cuir chevelu. A propos d'un cas.

Dermoïd cysts are benign tumours, resulting of an embryologic defect. They usually have good prognosis, only a single case of malignant transformation of a sublingual dermoid cyst has been brought back in literature. We report a case of carcinomatous transformation of a dermoïd cyst of the scalp, in a 54 years old man.