Patient-perceived outcomes of different anaesthetic techniques in classical surgical treatment of varicose veins of lower limbs.

AIM OF THE STUDY: To evaluate the effects of spinal or locoregional anaesthesia versus local tumescent anesthesia during traditional surgical treatment of saphenous reflux, in terms of pain and postoperative functional recovery. MATERIALS AND METHODS: From January to December 2014, 195 consecutive interventions of stripping of the greater saphenous vein for valvular incompetence were performed. In 114 cases spinal or locoregional anaesthesia was performed (group 1), in the remaining 81 cases local anaesthesia with the tumescence technique was carried out (group 2). All patients underwent an assessment of perceived pain by means of verbal rating scale before and at the end of surgery, at discharge and after a month. The times of recovery of ambulation during hospital stay and at the discharge were recorded and use of analgesic drugs during hospitalization and at home. At the end of the study, patients were asked to express their approval rating on the type of anaesthesia. RESULTS: Patients in group 2 experienced mild to moderate intraoperative pain more frequently than patients in group 1 (p<0.001), while patients in group 1 had more mild adverse anaesthesia-related events than patients in group 2. Patients in group 2 had faster recovery of ambulation and earlier discharge than patients in group 1.Thirty-day results were similar in the two groups; however, patients in group 2 had a higher degree of satisfaction than patients in group 1 with regard to the type of anaesthesia (p<0.001) CONCLUSIONS: Both locoregional and local tumescent anaesthesia are effective and well accepted by the patients, with similar intra-hospital and 30-day results. KEY WORDS: Great Saphenous Vein, Local tumescent anaesthesia, Pain, Stripping.

A 33-year experience with surgical management of popliteal artery aneurysms.

OBJECTIVE: This study retrospectively analyzed our 33-year experience with surgical management of popliteal artery aneurysms (PAAs), with particular attention paid to early and long-term results. METHODS: From January 1981 to December 2013, 234 open surgical interventions for PAA were performed in 196 patients. Data concerning these interventions were collected in a dedicated database containing main preoperative, intraoperative, and postoperative features. Early (intraoperative and <30 days) results were analyzed for mortality, thrombosis, reintervention, and amputation rates. The follow-up program consisted of clinical and duplex ultrasound examinations at 1 month and yearly thereafter. Patients who did not accomplish follow-up examinations were interviewed by telephone. Additional data regarding long-term survival and major clinical events were obtained from the Regional Health Care database. Follow-up results were analyzed for survival, primary and secondary patency, and amputations rates. RESULTS: Patients were predominantly males (186 [95%]), with a mean age of 68.5 ± 9.9 years. The PAA was asymptomatic in 97 limbs, intermittent claudication was present in 68, and limb-threatening ischemia was present in 62. Aneurysmal rupture occurred in six patients, and venous compression with leg swelling and pain was present in one patient. The intervention consisted of aneurysmal ligation and bypass grafting in 122 interventions, aneurysmectomy with graft interposition was used in 108, and four patients underwent aneurysmectomy with an end-to-end anastomosis. An autologous vein was used in 49 interventions, and a prosthetic graft was used in 181. In 71 interventions a posterior approach was used, and in the remaining 163, a medial approach was preferred. There were two perioperative deaths, with a cumulative mortality rate of 1%. Perioperative thrombosis occurred after 18 interventions (7.7%). A successful reintervention was performed in 10 of those patients, whereas surgical thrombectomy was ineffective in one patient and leg amputation was necessary. The remaining seven patients underwent major amputation without any new surgical attempt. An adjunctive major amputation was necessary in a patient with a patent bypass for irreversible foot ischemia. The cumulative rate of amputations at 30 days was 3.8% (9 of 234 limbs). Mean duration of follow-up was 62 months (range 1-312 months). During follow-up, 31 deaths, 45 thromboses, and 10 amputations were recorded. The estimated 13-year survival rate was 50.8% (standard error [SE], 0.07%); during the same interval, primary patency, secondary patency, and limb preservation rates were 55.1% (SE, 0.05%), 68% (SE, 0.05%), and 86% (SE, 0.04%). CONCLUSIONS: Open surgical repair of PAAs provided good results in our experience, with low rates of perioperative complications and an excellent durability in the very long-term setting, representing the benchmark for alternative techniques such as endovascular repair.

Combined carotid and cardiac surgery: improving the results.

BACKGROUND: Aim of this study was to analyze our experience in the last 5 years of combined carotid and cardiac surgery. METHODS: During a 5-year period (January 2002-December 2006), 111 patients underwent combined carotid endarterectomy (CEA) and coronary artery bypass grafting (CABG) (group 1), while 1,446 patients underwent isolated CEA (group 2). Perioperative outcomes in the two groups were compared using chi(2) and Fisher's exact tests to analyze neurological deficits, cardiac events, and death at 30 days. Results during follow-up were analyzed using Kaplan-Meier survival curves, and both groups were compared using the log-rank test. RESULTS: Immediate postoperative neurological deficits occurred more frequently in group 1 patients (2.5 vs. 0.4%, p = 0.002), with a higher incidence of transient ischemic attacks in group 1; however, there was no difference in the incidence of stroke (1% group 1 vs. 0.6% group 2, p = n.s.). Mortality rate was increased in the combined surgery group (3.5 vs. 0.5%, p < 0.001). Combined stroke/myocardial infarction/death rate at 30 days was 6.3% in group 1 compared with 1.4% in group 2, p = 0.001. Perioperative stroke/myocardial infarction/death rate was much improved in the 55% (61/111) of patients undergoing CABG off-pump (3.3 vs. 10%, p = 0.001). Mean follow-up was 18.7 months (range, 1-60). Survival at 24 months was significantly higher in patients of group 2 compared with group 1 (99.4 vs. 91.3% respectively, p < 0.001). At 24 months, there was no significant difference between the two groups in the risk of developing ipsilateral or contralateral neurologic events (3.1% group 1 vs. 1.7% group 2). CONCLUSION: In our experience, combined CEA and cardiac surgery carries a higher risk of perioperative mortality than patients undergoing isolated CEA. Whenever possible, CEA combined with off-pump CABG seems to be the therapeutic strategy of choice.