RESUMO
The paper presents the results of a study of selenium levels in the blood of apparently healthy residents aged 18 to 59 years in technogenically polluted areas (Dnepropetrovsk, Ukraine). In women, the selenium levels have been ascertained to be 5-13% higher than those in men. The selenium status in the examinees corresponds to an average of the suboptimal level and 16% lower than the optimal one and significantly lower than that in the control area.
Assuntos
Poluição Ambiental/efeitos adversos , Indústrias , Vigilância da População , Selênio/sangue , Adolescente , Adulto , Fatores Etários , Eritrócitos/enzimologia , Feminino , Glutationa Peroxidase/sangue , Glutationa Peroxidase/metabolismo , Humanos , Masculino , Pessoa de Meia-Idade , Selênio/deficiência , Fatores Sexuais , Ucrânia , Adulto JovemRESUMO
In order to evaluate the role of heavy metals in the reproductive status, a complex hygienic evaluation of total daily entry of lead, cadmium, zinc, and copper in the organism, biomonitoring of metals in indicator biosubstrates, and epidemiological follow-up of the reproductive function were carried out in 6962 healthy women living in industrial cities of the Dnepropetrovsk region. Total daily entry of lead is 0.27 mg, that of cadmium 0.029 mg, which meets the WHO requirements. However the entry of copper and particularly zinc is 1.5-3 times below the physiological norm. Biomonitoring showed high concentrations of lead and cadmium in the body. Regular entry of abiotic metals even in low concentrations in the presence of deficiency of essential metals is fraught with risk of reproductive diseases, which was proven mathematically for all stages of the reproductive function: gestation, labor, and neonatal period.
Assuntos
Ameaça de Aborto/etiologia , Metais Pesados/efeitos adversos , Complicações do Trabalho de Parto/etiologia , Complicações na Gravidez/etiologia , Ameaça de Aborto/epidemiologia , Área Programática de Saúde , Feminino , Humanos , Complicações do Trabalho de Parto/epidemiologia , Gravidez , Complicações na Gravidez/epidemiologia , Estudos Retrospectivos , Ucrânia/epidemiologiaRESUMO
Analysis of data on chronic toxicity of chemical elements and their metabolism in the human organism show the actual equality of the maximum ineffective dose and the daily dose. Authors considered, that the 2-fold excess of actual dose is not harmful for the human health.
