1.
J Org Chem
; 73(15): 5996-9, 2008 Aug 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-18598085
RESUMO
(R)-amino alcohol with an enantiomeric excess of >95% was resolved by reactive extraction processes from 2 equiv of racemic alcohol using a chiral receptor 2 as an enantioselective extractant. One resolution cycle is composed of three extractions: a stereoselective reversible imine formation, a stereoselective irreversible imine hydrolysis, and the recovery of 2 and enantiomeric amino alcohols.