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Forensic Sci Int ; 131(2-3): 85-9, 2003 Jan 28.
Artigo em Inglês | MEDLINE | ID: mdl-12590044

RESUMO

Eleven Italian forensic laboratories participated in a population study based on the AB Profiler Plus loci with proficiency testing. The validated database, including 1340 individuals, is available on-line. Tests for Hardy-Weinberg equilibrium, gametic unbalance, and heterogeneity of gene frequency were generally not significant. Gene frequencies at each locus were consistent with those of two previously published Italian studies, but different from a third. Individuals of each subsample were paired, and the total number of alleles shared across the nine loci was determined in each pair. The analysis was replicated over the total sample. In addition, two samples of mother-child pairs (N=315) and full-sib pairs (N=91) were subjected to allele sharing analysis. The resulting distributions were sufficiently distinct from the sample of unrelated pairs as to be of practical usefulness.


Assuntos
Frequência do Gene , Ligação Genética , Genética Populacional , Impressões Digitais de DNA/métodos , Bases de Dados Genéticas , Feminino , Humanos , Itália , Núcleo Familiar , Reação em Cadeia da Polimerase/métodos
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