RESUMO
Serum 25/OH/D3 levels were determined in 58 children aged 5-7 years staying from April 1 to September 30 1981 in Kolobrzeg in a sanatorium. A comparison of isolation conditions in that time period with the serum values of 25/OH/D3 showed that the supply of vitamin D was sufficient only in the period from June to September. In the remaining months no correlation was observed between the values of solar radiation and vitamin D levels. During the study and for three months before it exogenous vitamin D administration was stopped.
Assuntos
Luz Solar , Vitamina D/metabolismo , Calcifediol/sangue , Criança , Pré-Escolar , Humanos , Pacientes Internados , Infecções Respiratórias/terapia , Estações do Ano , Pele/metabolismo , Raios UltravioletaRESUMO
Comparison of the mechanism of action Vitamin D3 and 1 alpha-OH D3 under conditions of experimental hypercalcemia. Acta Physiol. Pol. 1979, 30 (2): 313--318. The hypercalcemic effect of supraphysiological doses of Vitamin D and 1 alpha-OH D3 were compared applying an animal model. Changes in serum calcium of animals with normal dietary calcium supplementation and those under conditions of calcium depletion were analyzed. Dietary calcium is necessary for the hypercalcemic effect of Vitamin D, whereas in case of 1 alpha-OH D3 calcium is mobilized not only from the dietary but also from some other sources. The analysis of the hypercalcemia kinetics in the Vitamin D and 1 alpha-OH D3 treated animals indicated that the kidney 1 hydroxylase of 25 hydroxycholecalciferol is an important step in the hypercalcemia preventing mechanism.
