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1.
Spectrochim Acta A Mol Biomol Spectrosc ; 206: 506-511, 2019 Jan 05.
Artigo em Inglês | MEDLINE | ID: mdl-30176426

RESUMO

In this paper, for the first time type and texture of northern Serbian soils were examined using DRIFT spectroscopy. It was investigated whether it is possible to use the specular reflection of the quartz band for the purpose of the preliminary quantitative determination of texture properties. Investigation is conducted on the five most common soil types in Vojvodina: Arenosols, Fluvisols, Chernozems, Vertisols and Solonetz. Spectra were obtained using diffuse reflectance (DRIFT) technique in mid-IR. Spectral characteristics for five characteristic soil types in this region were determined. Certain regularities were observed regarding inorganic bands and main relations between these inorganic components and the texture parameters were determined. The empirical equation for the rough preliminary estimation of the soil texture was determined based on the absorbance values on the 2228 and 1211 cm-1.

2.
J Biol Regul Homeost Agents ; 31(3): 667-672, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-28954469

RESUMO

Semi-essential amino acid L-arginine may be of fundamental importance in various intracellular and intercellular pathways related to skin repair and wound healing. Our current study was aimed to explore the effect of L-arginine on skin fibroblast (L929) signaling pathways involved in cell proliferation (Akt-pAkt kinase, Erk/pErk1/2 kinase, JNK/pJNK kinase and pStat-1), apoptosis (Bcl2 and Bax) and immune defense (NF-κB and CD26). Significant upregulation of Erk (p<0.011), pErk (p<0.017) and JNK (p<0.002) was documented, while the rise was not significant for pJNK kinase. The Akt/pAkt signaling pathway did not change significantly for the above-mentioned time and dose, while pStat-1 was significantly down regulated (p<0.011). The exposure of skin fibroblasts to L-arginine increased anti-apoptotic Bcl2/Bax stoichiometry ratio (p<0.05), obtained by calculation of their individual quantities. L-arginine was able to elicit NF-κB signaling through the increase of p65 active subunit level (p<0.004), while CD26 surface antigen level was not significantly changed. In conclusion, the exposure of skin fibroblasts to L-arginine may help in maintaining and stimulating skin fibroblast proliferative, anti-apoptotic and immune defense function. Therefore, the proposed L-arginine dose may be used for tissue regeneration application, which would be of importance in regenerative medicine, skin rejuvenation approaches and wound healing.


Assuntos
Apoptose/efeitos dos fármacos , Arginina/farmacologia , Fibroblastos/metabolismo , Proteínas Proto-Oncogênicas c-akt/efeitos dos fármacos , Pele/metabolismo , Animais , Linhagem Celular , Proliferação de Células , Dipeptidil Peptidase 4/metabolismo , Fibroblastos/citologia , MAP Quinase Quinase 4/metabolismo , Camundongos , Proteína Quinase 3 Ativada por Mitógeno/metabolismo , Proteínas Proto-Oncogênicas c-bcl-2/metabolismo , Fator de Transcrição STAT1/metabolismo , Pele/citologia , Fator de Transcrição RelA/metabolismo , Proteína X Associada a bcl-2/metabolismo
3.
Sci Total Environ ; 571: 398-409, 2016 Nov 15.
Artigo em Inglês | MEDLINE | ID: mdl-27473773

RESUMO

We considered temporal and spatial variations to the thermal and moisture regimes of the most common RSGs (Reference Soil Groups) in Serbia under the A1B scenario for the 2021-2050 and 2071-2100 periods, with respect to the 1961-1990 period. We utilized dynamically downscaled global climate simulations from the ECHAM5 model using the coupled regional climate model EBU-POM (Eta Belgrade University-Princeton Ocean Model). We analysed the soil temperature and moisture time series using simple statistics and a Kolmogorov complexity (KC) analysis. The corresponding metrics were calculated for 150 sites. In the future, warmer and drier regimes can be expected for all RSGs in Serbia. The calculated soil temperature and moisture variations include increases in the mean annual soil temperature (up to 3.8°C) and decreases in the mean annual soil moisture (up to 11.3%). Based on the KC values, the soils in Serbia are classified with respect to climate change impacts as (1) less sensitive (Vertisols, Umbrisols and Dystric Cambisols) or (2) more sensitive (Chernozems, Eutric Cambisols and Planosols).

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