Assuntos
Testes de Liberação de Interferon-gama/métodos , Mycobacterium tuberculosis/isolamento & purificação , Guias de Prática Clínica como Assunto , Teste Tuberculínico/métodos , Tuberculose/diagnóstico , Fatores Etários , Austrália , Países em Desenvolvimento , Feminino , Humanos , Incidência , Masculino , Pediatria , Medição de Risco , Tuberculose/epidemiologia , Estados Unidos , Organização Mundial da SaúdeAssuntos
Infecções por Citomegalovirus/prevenção & controle , Programas de Rastreamento/métodos , Antivirais/uso terapêutico , Citomegalovirus/genética , Infecções por Citomegalovirus/congênito , Infecções por Citomegalovirus/diagnóstico , Vacinas contra Citomegalovirus/administração & dosagem , Feminino , Humanos , Recém-Nascido , GravidezRESUMO
A method is described to perform automated mapping of hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) particles in C-4 fingerprints. The method employs polarized light microscopy and image analysis to map the entire fingerprint and the distribution of RDX particles. This method can be used to evaluate a large number of fingerprints to aid in the development of threat libraries that can be used to determine performance requirements of explosive trace detectors. A series of 50 C-4 fingerprints were characterized, and results show that the number of particles varies significantly from print to print, and within a print. The particle size distributions can be used to estimate the mass of RDX in the fingerprint. These estimates were found to be within +/-26% relative of the results obtained from dissolution gas chromatography/micro-electron capture detection for four of six prints, which is quite encouraging for a particle counting approach. By evaluating the average mass and frequency of particles with respect to size for this series of fingerprints, we conclude that particles 10-20 microm in diameter could be targeted to improve detection of traces of C-4 explosives.