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1.
Cutis ; 86(2): 89-93, 2010 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-20919603

RESUMO

Oral mucosal melanoma is rare and is reported to be more aggressive than cutaneous melanoma. The incidence of oral mucosal melanoma peaks at 41 to 60 years of age and the male to female ratio is 2 to 1. Preferred sites in the oral mucosa include the hard palate and maxillary alveolar crests. Risk factors have not been clearly identified, but melanotic pigmentation is present in one-third of patients prior to the diagnosis of melanoma. We report an unusual case of oral mucosal melanoma of the mandibular gingiva with the main characteristics of an in situ lesion and areas of superficial invasion in a 45-year-old woman. The patient was treated with surgical resection of the lesion and a 54-month follow-up shows no evidence of recurrence. Oral mucosal melanomas are aggressive neoplasms that may arise from prior pigmented lesions in the oral mucosa. Classification of these tumors is not well-established and the main prognostic factor appears to be lymph node compromise. The main treatment modality is surgical resection.


Assuntos
Neoplasias Gengivais/diagnóstico , Melanoma/diagnóstico , Diagnóstico Diferencial , Feminino , Neoplasias Gengivais/patologia , Neoplasias Gengivais/cirurgia , Humanos , Mandíbula , Melanoma/patologia , Melanoma/cirurgia , Pessoa de Meia-Idade
2.
Int J Dermatol ; 45(2): 124-6, 2006 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-16445501

RESUMO

The present report describes a case of cutaneous protothecosis caused by Prototheca wickerhamii in a nonimmunocompromised Brazilian female. Dermatological examination revealed a 15-cm diffusely infiltrated eczema-like plaque recovered with many pustule-like lesions on the right forearm. We emphasize the mycological and pathological aspects of this infection that can lead to misdiagnosis. The patient was successfully treated with itraconazole.


Assuntos
Infecções/diagnóstico , Prototheca/isolamento & purificação , Dermatopatias Infecciosas/diagnóstico , Idoso , Antifúngicos/uso terapêutico , Feminino , Antebraço , Humanos , Imunocompetência , Infecções/tratamento farmacológico , Itraconazol/uso terapêutico , Dermatopatias Infecciosas/tratamento farmacológico
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