A randomized controlled trial of a tablet-based intervention to address predonation fears among high school donors.

BACKGROUND: Prior studies have shown donation-related fear to be associated with decreased donor confidence and an increased risk for vasovagal reactions. This study examined the effects of a predonation intervention that provided fearful donors with suggestions for coping. STUDY DESIGN AND METHODS: Using a tablet-based application, high school donors (49.4% female) answered a question regarding their fear of having blood drawn. Those who reported fear were randomly assigned to either a control (n = 930) or an intervention (n = 911) group. Donors in the control group rated their confidence in dealing with their fear and then donated as usual. Donors in the intervention group received a brief audiovisual presentation on coping strategies, rated their confidence, and then donated as usual. RESULTS: A higher proportion of fearful versus nonfearful donors experienced a vasovagal reaction, even after controlling for other demographic and health predictors (OR, 2.3; 95% CI, 1.655-3.185, p < 0.001). Fearful donors who received the intervention reported greater confidence than controls, but the proportion of vasovagal reactions did not differ significantly between the intervention (6.1%) and control (6.8%) groups. CONCLUSION: Although the current tablet-based intervention may have some psychological benefit in that it was associated with greater donor confidence, the observed effect was small and did not translate into a lower risk for vasovagal reactions. However, greater confidence among young donors may lead to an increased willingness to donate again-a potential outcome that we will revisit among these donors as part of a planned 2-year follow-up.

Predonation fears identify young donors at risk for vasovagal reactions.

BACKGROUND: Extending existing research on the relationship between predonation fear of having blood drawn and risk for vasovagal reactions among young donors, this study assessed the predictive power of specific donation-related fears. STUDY DESIGN AND METHODS: After the health screening, high school whole blood donors (59.5% female) were randomly assigned into one of three groups. Group 1 (n = 881) answered a control question about their prior night's sleep. Group 2 (n = 911) answered the sleep question and a question about fear of having blood drawn. Group 3 (n = 924) answered the sleep question, the fear of having blood drawn question, and four questions about specific donation-related fears (seeing blood, needles, pain, and fainting). RESULTS: The proportion of vasovagal reactions did not differ significantly among the groups, indicating that asking one or more fear questions before donation did not promote reactions. Fearful donors were more likely to have a vasovagal reaction, even after controlling for other important demographic and health predictors, with odds ratios ranging from 2.17 (95% confidence interval [CI], 1.44-3.27) for fear of fainting to 3.50 (95% CI, 2.34-5.23) for fear of seeing blood. Hours of sleep was not significantly related to vasovagal reaction risk. CONCLUSION: Predonation fear identifies donors who are more likely to experience a vasovagal reaction and does so without increasing the risk of such reactions. Accordingly, fear should be assessed during screening to identify those who could benefit from instruction in anxiety management and who might require greater attention to help prevent donor injury.

Effects of respiratory and applied muscle tensing interventions on responses to a simulated blood draw among individuals with high needle fear.

Fear of blood and needles increases risk for presyncopal symptoms. Applied muscle tension can prevent or attenuate presyncopal symptoms; however, it is not universally effective. This study examined the effects of applied muscle tension, a respiratory intervention, and a no treatment control condition, on presyncopal symptoms and cerebral oxygenation, during a simulated blood draw with individuals highly fearful of needles. Participants (n = 95) completed questionnaires, physiological monitoring, and two trials of a simulated blood draw with recovery. Presyncopal symptoms decreased across trials; however, no group differences emerged. Applied muscle tension was associated with greater cerebral oxygenation during trial two, and greater end-tidal carbon dioxide during both trials. The respiratory intervention did not differ from the no treatment control. Applied muscle tension is an intervention that can increase cerebral oxygenation and end-tidal carbon dioxide. While the respiratory intervention is promising within therapeutic settings, it was not efficacious after a brief audio training.

Enhancing cerebral oxygenation during blood donation using biofeedback.

Biofeedback of cerebral oxygenation was used to guide application of applied muscle tension during whole blood donation, and resulted in attenuated reductions compared to donors who did not receive feedback.

A stiffness discrimination experiment including analysis of palpation forces and velocities.

INTRODUCTION: The incorporation of haptics, the sense of touch, into medical simulations increases their capabilities by enabling the users to "feel" the virtual environment. We are involved with haptics-augmented virtual reality training for palpatory diagnosis. We have developed a stiffness discrimination program to train and test users in finding subtle differences in human tissue stiffness for medical diagnoses. In this article, we studied the effect of surface stiffness on the stiffness discrimination task and analyzed the palpation force and speed during haptic exploration. METHODS: The ability to discriminate stiffness differences was studied by means of a psychophysical experiment with 13 second-year medical students (eight women and five men). Subjects were asked to identify the stiffer of two virtual computer-generated surfaces (top surfaces of two cylinders) by means of a PHANToM Omni (SensAble Inc.) haptic device with a modified stylus to accommodate their fingers. The modification of the stylus provided the mechanical advantage to simulate surface stiffness values that are beyond the original capability of the haptic device. An adaptive two-alternative forced-choice procedure was used on each trial. Palpation velocity and force vectors were recorded directly from the haptic device for further analyses. Weber fraction was determined by using an automated mastery algorithm. RESULTS: Four standard stiffness values (0.25, 0.50, 1.00, and 1.25 N/mm), typical of the stiffness range of human soft tissues, were used as references. The average experimental Weber fractions observed were 0.20, 0.27, 0.26, and 0.30, respectively, with higher Weber fractions corresponding to lower stiffness discrimination ability. At 1.00 and 1.25 N/mm standard stiffness, the correlation analysis for Weber fraction and the palpation speed revealed significant differences (P < 0.05). These differences suggested that the subjects with a higher palpation velocity tended to have a higher Weber fraction. There was no significant difference between male and female subjects. There was no significant difference between subjects new to the haptic device and those who had used it previously. The average amount of force that was applied by the subjects to the standard stiffness side and the comparison stiffness side within the sessions was not significantly different. However, the subjects increased the average force they applied with increasing standard stiffness value across the sessions (P < 0.05). CONCLUSIONS: For the four standard stiffness values investigated, 0.25, 0.50, 1.00, and 1.25 N/mm, the resulting average stiffness-discrimination Weber fractions were 0.20, 0.27, 0.26, and 0.30, respectively. The average of the forces applied by the subjects was constant within a single session (with a single standard stiffness value). This average force monotonically increased as the standard stiffness value increased across the sessions. We also found positive correlation between the Weber fraction and the palpation speed in the sessions tested with 1.00 and 1.25 N/mm standard stiffness. This correlation suggested that higher speed is related to lower sensitivity in discrimination of stiffness differences for these two standard stiffness values. Our results are applicable to tasks involving stiffness discrimination between multiple objects.

Muscle functional magnetic resonance imaging and acute low back pain: a pilot study to characterize lumbar muscle activity asymmetries and examine the effects of osteopathic manipulative treatment.

BACKGROUND: Muscle functional magnetic resonance imaging (mfMRI) measures transverse relaxation time (T2), and allows for determination of the spatial pattern of muscle activation. The purposes of this pilot study were to examine whether MRI-derived T2 or side-to-side differences in T2 (asymmetries) differ in low back muscles between subjects with acute low back pain (LBP) compared to asymptomatic controls, and to determine if a single osteopathic manipulative treatment (OMT) session alters these T2 properties immediately and 48-hours after treatment. METHODS: Subjects with non-specific acute LBP (mean score on 110 visual analog score = 3.02 +/- 2.81) and asymptomatic controls (n = 9/group) underwent an MRI, and subsequently the LBP subjects received OMT and then underwent another MRI. The LBP subjects reported back for an additional MRI 48-hours following their initial visit. T2 and T2 asymmetry were calculated from regions of interest for the psoas, quadratus lumborum (QL), multifidus, and iliocostalis lumborum/longissimus thoracis (IL/LT) muscles. RESULTS: No differences were observed between the groups when T2 was averaged for the left and right side muscles. However, the QL displayed a significantly greater T2 asymmetry in LBP subjects when compared to controls (29.1 +/- 4.3 vs. 15.9 +/- 4.1%; p = 0.05). The psoas muscle also displayed a relatively large, albeit non-significant, mean difference (22.7 +/- 6.9 vs. 9.5 +/- 2.8%; p = 0.11). In the subjects with LBP, psoas T2 asymmetry was significantly reduced immediately following OMT (25.3 +/- 6.9 to 6.1 +/- 1.8%, p = 0.05), and the change in LBP immediately following OMT was correlated with the change in psoas T2 asymmetry (r = 0.75, p = 0.02). CONCLUSION: Collectively, this pilot work demonstrates the feasibility of mfMRI for quantification and localization of muscle abnormalities in patients with acute low back pain. Additionally, this pilot work provides insight into the mechanistic actions of OMT during acute LBP, as it suggests that it may attenuate muscle activity asymmetries of some of the intrinsic low back muscles.

The virtual haptic back: a simulation for training in palpatory diagnosis.

BACKGROUND: Models and simulations are finding increased roles in medical education. The Virtual Haptic Back (VHB) is a virtual reality simulation of the mechanical properties of the human back designed as an aid to teaching clinical palpatory diagnosis. METHODS: Eighty-nine first year medical students of the Ohio University College of Osteopathic Medicine carried out six, 15-minute practice sessions with the VHB, plus tests before and after the sessions in order to monitor progress in identifying regions of simulated abnormal tissue compliance. Students palpated with two digits, fingers or thumbs, by placing them in gimbaled thimbles at the ends of PHANToM 3.0(R) haptic interface arms. The interface simulated the contours and compliance of the back surface by the action of electric motors. The motors limited the compression of the virtual tissues induced by the palpating fingers, by generating counterforces. Users could see the position of their fingers with respect to the back on a video monitor just behind the plane of the haptic back. The abnormal region varied randomly among 12 locations between trials. During the practice sessions student users received immediate feedback following each trial, indicating either a correct choice or the actual location of the abnormality if an incorrect choice had been made. This allowed the user to feel the actual abnormality before going on to the next trial. Changes in accuracy, speed and Weber fraction across practice sessions were analyzed using a repeated measures analysis of variance. RESULTS: Students improved in accuracy and speed of diagnosis with practice. The smallest difference in simulated tissue compliance users were able to detect improved from 28% (SD = 9.5%) to 14% (SD = 4.4%) during the practice sessions while average detection time decreased from 39 (SD = 19.8) to 17 (SD = 11.7) seconds. When asked in anonymous evaluation questionnaires if they judged the VHB practice to be helpful to them in the clinical palpation and manual medicine laboratory, 41% said yes, 51% said maybe, and 8% said no. CONCLUSION: The VHB has potential value as a teaching aid for students in the initial phases of learning palpatory diagnosis.

Repeated palpatory training of medical students on the Virtual Haptic Back.

The effectiveness of simulation-based training has been accepted with great success in many fields including medicine. Most of the simulation research and development in medicine has focused on surgery. There has been some development of hardware based biomechanical models of sections of human anatomy, such as pelvic exam simulators. More recently, with the advances in haptics technology, software and hardware based simulators are being developed for the previously ignored area of palpatory diagnosis. The Virtual Haptic Back (VHB) is a simulator based on virtual reality and haptics that is currently being used to train medical students in palpatory diagnosis. This study examined the effect of repeating the training on the VHB.

Palpatory diagnosis training on the virtual haptic back: performance improvement and user evaluations.

CONTEXT: Learning palpatory diagnosis is a challenge for many osteopathic medical students. The Virtual Haptic Back (VHB) is an aid in teaching and learning these skills. The device simulates the contours and surface compliances of the human back and allows these to be felt through haptic interfaces. Regions of abnormal tissue texture are simulated by altered surface compliance. OBJECTIVES: To examine the effectiveness of the VHB in training osteopathic medical students in palpatory diagnosis and to determine students' subjective impressions of the potential value of the VHB in learning palpatory diagnosis. METHODS: Twenty-one first-year osteopathic medical students at the Ohio University College of Osteopathic Medicine in Athens took performance tests on the VHB before and after a series of eight 15-minute practice sessions, which occurred during multiple 2-week sessions between September 2005 and January 2006. The tests and practice sessions measured student accuracy and speed in locating regions of abnormal compliance in the haptic back, which varied randomly among 12 sites in the thoracic region. After completing the practice sessions and performance tests, students filled out a questionnaire regarding their impressions of the potential value of the VHB as a learning aid. RESULTS: Students collectively improved in accuracy and speed following the practice sessions compared with the initial performance test. Subjects improved from being able to detect only a 40% difference in compliance to being able to detect an 11% difference (P<.05). The greatest improvements occurred at the difficulty levels near the apparent detection limit of compliance differences. Survey responses indicated that students thought the VHB experience was helpful in developing their palpatory skills. CONCLUSION: The VHB has potential as an effective aid to osteopathic medical students in learning palpatory diagnosis.

Effect of counterstrain on stretch reflexes, hoffmann reflexes, and clinical outcomes in subjects with plantar fasciitis.

CONTEXT: Previous research indicates that osteopathic manipulative treatment based on counterstrain produces a decrease in the stretch reflex of the calf muscles in subjects with Achilles tendinitis. OBJECTIVES: To study the effects of counterstrain on stretch reflex activity and clinical outcomes in subjects with plantar fasciitis. METHODS: In a single-blind, randomized controlled trial of crossover design, the effects of counterstrain were compared with those of placebo in adult subjects (N=20) with plantar fasciitis. The subjects were led to believe that both the counterstrain and placebo were therapeutic modalities whose effects were being compared. Ten subjects (50%) were assigned to receive 3 weeks of counterstrain treatment during phase 1 of the trial, while the other 10 subjects were given placebo capsules. After a 2- to 4-week washout period, phase 2 of the trial began with the interventions reversed. Clinical outcomes were assessed with daily questionnaires. Stretch reflex and H-reflex (Hoffmann reflex) in the calf muscles were assessed twice during each laboratory visit, before and after treatment in the counterstrain phase. RESULTS: No significant changes in the electrically recorded reflexes of the calf muscles were observed in response to treatment. However, changes in the mechanical characteristics of the twitches resulting from the electrical responses were observed. Peak force and time to reach peak force both increased (P< or =.05) in the posttreatment measurements, with the increase being significantly more pronounced in the counterstrain phase (P< .05). A comparison of pretreatment and posttreatment symptom severity demonstrated significant relief of symptoms that was most pronounced immediately following treatment and lasted for 48 hours. CONCLUSIONS: Clinical improvement occurs in subjects with plantar fasciitis in response to counterstrain treatment. The clinical response is accompanied by mechanical, but not electrical, changes in the reflex responses of the calf muscles. The causative relation between the mechanical changes and the clinical responses remains to be explored.

Characteristics of physicians disciplined by the State Medical Board of Ohio.

Although physicians have been disciplined for a variety of offenses by state medical boards across the United States, limited information is available about the characteristics of these physicians. To assess the characteristics of, offenses committed by, and resulting disciplinary actions taken against a consecutive series of disciplined physicians in the state of Ohio, the authors conducted a case-control study of all 308 physicians publicly disciplined by the State Medical Board of Ohio (SMBO) from January 1997 to June 1999. Subjects were matched with two groups of control physicians--one matched by location only, and the second matched for location, gender, practice type, and self-designated specialty. The main outcomes measured were disciplinary actions, offenses leading to state medical board actions, and the characteristics of disciplined physicians. Of 340 physicians disciplined during these 30 months (approximately 0.37% per year), 308 committed 477 offenses requiring 409 actions by the SMBO. The most common offenses were impairment due to alcohol and/or drug use (21%), inappropriate prescribing or drug possession (14%), previous state actions (15%), negligence or incompetence (7%), and drug-related charges (7%). Although offenders were significantly less likely to be women (P < .05; odds ratio [OR], 0.46; 95% confidence interval [CI], 0.28-0.75), the authors found no difference in the severity of disciplinary action taken against offenders by gender (OR, 1.23; 95% CI, 0.54-2.82) or by type of medical training, ie, between osteopathic physicians and allopathic physicians (OR, 0.70; 95% CI, 0.39-1.26). Compared with controls matched for location, gender, practice type, and self-designated specialty, offenders were significantly less likely to be board certified (OR, 0.65; CI, 0.46-0.92) and significantly more likely to have been in practice 20 or fewer years (OR, 1.51; 95% CI, 1.08-2.13). Disciplinary actions in Ohio were more frequent, more severe, and more often in response to impairment due to alcohol and/or drug use and previous state actions than previously reported. No difference in the severity of disciplinary action was noted between men and women or between osteopathic and allopathic physicians.

The relationship between elbow flexor volume and angular stiffness at the elbow.

OBJECTIVE: The purpose of this experiment was to determine if a correlation exists between the volume of the elbow flexors and angular stiffness at the elbow, and to determine the contribution of the biceps brachii and the brachialis muscles to angular stiffness. DESIGN: This study is a descriptive, correlational study and presents a graphical model of the passive properties of muscle. BACKGROUND: The correlation between arm volume and angular stiffness has been shown, but the measurement of arm volume was not specific to the structures being strained. Pre-positioning a bi-articular muscle by stretching over one joint decreases the range of motion at the other joint and may affect the stiffness. METHODS: Angular stiffness at the elbow of 14 female and 15 male volunteers was measured, and the volume of the elbow flexors was calculated from compounded ultrasound imaging. Initial biceps length was set by pre-positioning the shoulder in two different positions. RESULTS: A significant linear relationship was observed between the slope of phase 1 of the stiffness curve and volume of the elbow flexors in both horizontal flexion (r = 0.92) and horizontal extension (r = 0.79) of the shoulder. Phase 2 of the stiffness curve showed no linear relationship to muscle volume in either shoulder position (flexion, r = 0.22; extension r = 0.33). The slopes of phases 1 and 2 were significantly greater with the shoulder in horizontal extension than in horizontal flexion. CONCLUSION: The volume of the elbow flexor muscles is a good predictor of angular stiffness in phase 1 of the curve. A model of the additive contribution of the biceps and brachialis muscles is presented to account for the increased stiffness in the shoulder extended position. RELEVANCE: Recognition of the correlation between muscle volume and stiffness, coupled with understanding that pre-positioning a bi-articular muscle may affect muscle stiffness may aid the clinician in accurately assessing muscle stiffness in patients with connective tissue disorders, neurological dysfunction and contractures.