RESUMO
Research on managerial voice endorsement has primarily focused on the processes and conditions through which voicers receive their managers' endorsement. We shift this focus away from the voicers, focusing instead on the dual reactions that endorsement generates for observing employees. Drawing from an approach-avoidance framework, we propose that managerial endorsement of coworker voice could be perceived as a positive and negative stimulus for observers, prompting them to approach opportunities and avoid threats, respectively. Results from a preregistered experiment and a multiwave, multisource field study revealed that managerial endorsement of coworker voice was positively related to observers' voice instrumentality, thus prompting them to engage in approach behaviors (i.e., voice). We also found that managerial endorsement of coworker voice was positively related to observers' voice threat, triggering avoidant behaviors (i.e., avoidance-oriented counterproductive work behaviors). Further, we found that the avoidant reactions more pronounced for observers with higher (vs. lower) neuroticism. Overall, our research extends theory by demonstrating the rippling effects that voice endorsement can ignite throughout the workgroup. (PsycInfo Database Record (c) 2024 APA, all rights reserved).
RESUMO
BACKGROUND: Erdheim Chester disease (MEC) is a rare non-Langerhans cell histiocytosis characterized by multi-visceral involvement. We report a case of MEC associated with Langerhans cell histiocytosis (HCL). CASE REPORT: A 46-year-old women presented skin and vulvar localization of HCL associated with typical MEC bone involvement. Despite chemotherapy (vinblastine) and prednisone, the disease progressed to involve the central nervous system, leading to fatal outcome. Post-mortem examination showed HCL in skin, MEC in bones and central nervous system, and intermediate histiocytic proliferation in the encephalon. DISCUSSION: Usually, MEC and HCL are considered as distinct entities. MEC is characterized by a xanthogranulomatous proliferation of CD 68+ foamy histiocytes nested in fibrosis, and HCL by a proliferation of PS 100+ and CD1a+ Langerhans cells. However, our observation, as well as previous reports, suggests that MEC is part of the HCL spectrum.
Assuntos
Histiocitose de Células de Langerhans/diagnóstico , Histiocitose de Células não Langerhans/diagnóstico , Doenças Ósseas/diagnóstico , Doenças Ósseas/patologia , Encefalopatias/diagnóstico , Encefalopatias/patologia , Diagnóstico Diferencial , Evolução Fatal , Feminino , Histiócitos/patologia , Histiocitose de Células de Langerhans/patologia , Histiocitose de Células não Langerhans/patologia , Humanos , Pessoa de Meia-Idade , Pele/patologia , Dermatopatias/diagnóstico , Dermatopatias/patologia , Doenças da Vulva/diagnóstico , Doenças da Vulva/patologiaRESUMO
Over 20 months, we have treated 74 patients (59 children less than 12 years of age) with port-wine stains (PWS) using a 585-nm flashlamp-pulsed dye laser (SPTL-1, Candela Corp., Wayland, Mass., USA) after topical anesthesia with Emla cream. A 5-point reference color scale was used to evaluate the results. 45 patients had at least one treatment on the entire surface of the lesion. A mean of 88 impacts per session was delivered. There was a significant decrease in color in around two thirds of the cases after one complete treatment with a gradual tendency to improvement after subsequent treatments. Younger age at the beginning of treatment was not found to be predictive of a better outcome after the first treatment. In around one third of the cases, positive test site treatment was not correlated with significant improvement after one treatment. Lesions situated on the limbs were less responsive than those on the head and neck. Except for problems due to absence of general anesthesia in young children enduring repeated stressful and sometimes painful procedures, the overall impression is that early treatment of PWS is possible with very limited risks of scarring using this technique.
Assuntos
Hamartoma/radioterapia , Terapia a Laser , Dermatopatias/radioterapia , Adolescente , Anestesia Local , Criança , Pré-Escolar , Sedação Consciente , Eritema/etiologia , Extremidades/patologia , Dermatoses Faciais/patologia , Dermatoses Faciais/radioterapia , Feminino , Hamartoma/patologia , Humanos , Hiperpigmentação/etiologia , Lactente , Lasers/efeitos adversos , Masculino , Dermatopatias/patologia , Pigmentação da Pele/efeitos da radiaçãoRESUMO
In children as well as in adults, capillaroscopy is an unsophisticated and non invasive technique which allows to investigate vascular acrosyndromes and systemic diseases. We have studied nailfold capillaroscopy patterns in 80 children without over vascular or systemic disease: pericapillary halos and haemorrhages increased with age and capillaries matured towards the typical hair pin structure seen in adults. The number of minor dystrophies increased with age and the venous subpapillary plexuses became less easily visible.
Assuntos
Dedos/diagnóstico por imagem , Unhas , Adolescente , Adulto , Capilares/diagnóstico por imagem , Criança , Pré-Escolar , Dermatomiosite/diagnóstico por imagem , Dermatomiosite/patologia , Dedos/irrigação sanguínea , Humanos , Lactente , Recém-Nascido , Lúpus Eritematoso Sistêmico/diagnóstico por imagem , Lúpus Eritematoso Sistêmico/patologia , Radiografia , Valores de Referência , Escleroderma Sistêmico/diagnóstico por imagem , Escleroderma Sistêmico/patologia , Fatores de TempoRESUMO
Seventeen cases of pityriasis lichenoides diagnosed over a nine-year period in children under 15 years of age are reported. Patients with this benign disease develop papular skin lesions covered with thick, coherent scales which detach in a single piece (reminiscent of sealing wax). Pruritus is not marked. Lesions may be necrotic (Mucha Habermann's small pox-like form, n = 6) or mild (leukodermic form, n = 2). Half of the patients studied developed several episodes and total duration of the disease exceeded two years in one third of cases. Recovery occurred after one or two episodes in half the children. Scars developed in some patients with severely necrotic lesions. None of the patients developed lymphoma. All patients with lymphomatoid papulosis progressing to lymphoma reported in the literature were adults. Pathogenesis of pityriasis lichenoides remains unknown but may involve lymphocytic vasculitis. No truly effective therapy is available. However, oral macrolides can be used especially in patients with early manifestations suggesting an infectious disease. Emollients, heliotherapy and ultraviolet therapy may also be recommended.
Assuntos
Parapsoríase/patologia , Pitiríase/patologia , Adolescente , Antibacterianos/administração & dosagem , Antibacterianos/uso terapêutico , Biópsia , Criança , Pré-Escolar , Feminino , Helioterapia , Humanos , Macrolídeos , Masculino , Necrose , Parapsoríase/etiologia , Parapsoríase/terapia , Pitiríase/etiologia , Pitiríase/terapia , Estudos Retrospectivos , Terapia UltravioletaRESUMO
A living cellular allogeneic dressing made up of cultured keratinocytes adhering to a collagen film was used to treat 20 leg ulcers of various aetiologies in 16 patients. A reduction in pain was noted in 80% of cases, and promotion of granulation tissue in the ulcer bed in 70% of cases. In 10 patients, epithelialization of 71 +/- 29% of the ulcer was noted at Day 30.