1.
Org Biomol Chem
; 11(34): 5579-83, 2013 Sep 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23863943
RESUMO
A synthetic glycoarray containing non-reducing α-galactopyranosyl moieties related to mucin O-glycans of the parasite Trypanosoma cruzi was evaluated by a chemiluminescent enzyme-linked immunosorbent assay with sera from patients with chronic Chagas disease. Our data revealed the disaccharide Galα(1,3)Galß as the immunodominant glycotope, which may eventually be employed as a diagnostic antigen for Chagas disease.