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1.
Arch Esp Urol ; 73(4): 257-267, 2020 May.
Artigo em Espanhol | MEDLINE | ID: mdl-32379060

RESUMO

INTRODUCTION: Urosepsis is an underdiagnosed entity with high morbidity and mortality and significant associated costs. The delay in diagnosis leads to an increased risk of multiorgan failure and death. Although its prognosis is better than that of other sepsis, the mortality rate is 20 - 40%. OBJECTIVE: Describe the obstructive uropathy cases (OU) that are complicated by severe sepsis (SS) and identify early biomarkers of SS. MATERIAL AND METHODS: Observational and prospective study of 65 patients with urgent high OU. All patients were evaluated at three different times (0, 24 and 48 hours). An SS predictor model has been constructed and a multivariate risk analysis has been carried out. RESULTS: 64.61% (n=42) developed SS (NSS: n=13). The only statistically significant variables in the 3 moments evaluated and that obtained a good area under the curve [AUROC (>0.70)] were the elevation of neutrophils, procalcitonin, and decrease of bicarbonate. At the time of patient admission, the variable that best predicted SS was the elevation of procalcitonin (AUROC:0.919). SS risk factors (p<0.005) were the history of cancer immunosuppression, and/or urinary tract surgeries, complete UO and high blood values of lactate, potassium and decrease of bicarbonate. The potassium-lactate combination on admission predicted SS with a probability function of 0.805. CONCLUSIONS: There is an analytical profile maintained over the time characteristic of SS that allows anearly identification of patients with OU subsidiary of been complicated with SS.


INTRODUCCIÓN: La Sepsis urinaria obstructiva (SUO) es una entidad infradiagnosticada con una elevada morbimortalidad e importantes costes asociados. El retraso en su diagnóstico condiciona un mayor riesgo de fracaso multiorgánico y fallecimiento. Aunque su pronóstico es mejor que el de otros focos de sepsis, su mortalidad es del 20 - 40%. OBJETIVO: Describir los cuadros de uropatía obstructiva (UO) que se complican con sepsis grave (SG) e identificarlos biomarcadores diagnósticos de SG en la UOde forma precoz.MATERIAL Y MÉTODOS: Estudio observacional y prospectivo de 72 pacientes con UO alta ingresados de manera urgente en el Servicio de Urología del Hospital Clínico Universitario de Valladolid. Todos los pacientes del estudio fueron evaluados en tres momentos diferentes (0, 24 y 48 horas). Se ha creado un modelo predictor de SG y se ha realizado un análisis multivariante de riesgo. RESULTADOS: El 64,61% de los pacientes (n=42) desarrolló SG (NSG: n=13). Las únicas variables estadísticamente significativas en los tres momentos evaluados y que obtenían una buena área bajo la curva [AUROC (>0,70)] fueron la elevación de neutrófilos y procalcitonina y la disminución de bicarbonato. En el momento del ingreso la variable que mejor predecía SG fue la elevación de procalcitonina (AUROC: 0,919). Los factores de riesgo de SG (p<0,05) fueron los antecedentes de cáncer, la inmunosupresión y/o cirugías de vías urinarias, la UO completa y los valores elevados en sangre de lactato y potasio y la disminución del bicarbonato en la gasometría venosa. La combinación potasio-lactato al ingreso predecía SG con una función de probabilidad de 0,805. CONCLUSIONES: Existe un perfil analítico, mantenido en el tiempo, característico de SG que permite la identificación precoz de los pacientes con UO subsidiarios de complicarse con SG.


Assuntos
Sepse , Choque Séptico , Infecções Urinárias , Biomarcadores , Humanos , Prognóstico , Estudos Prospectivos , Curva ROC
2.
Arch. esp. urol. (Ed. impr.) ; 73(4): 257-267, mayo 2020. tab, graf
Artigo em Espanhol | IBECS | ID: ibc-192985

RESUMO

INTRODUCCIÓN: La Sepsis urinaria obstructiva (SUO) es una entidad infradiagnosticada con una elevada morbimortalidad e importantes costes asociados. El retraso en su diagnóstico condiciona un mayor riesgo de fracaso multiorgánico y fallecimiento. Aunque su pronóstico es mejor que el de otros focos de sepsis, su mortalidad es del 20 - 40%. OBJETIVO: Describir los cuadros de uropatía obstructiva (UO) que se complican con sepsis grave (SG) e identificarlos biomarcadores diagnósticos de SG en la UOde forma precoz. MATERIAL Y MÉTODOS: Estudio observacional y prospectivo de 72 pacientes con UO alta ingresados de manera urgente en el Servicio de Urología del Hospital Clínico Universitario de Valladolid. Todos los pacientes del estudio fueron evaluados en tres momentos diferentes (0, 24 y 48 horas). Se ha creado un modelo predictor de SG y se ha realizado un análisis multivariante de riesgo. RESULTADOS: El 64,61% de los pacientes (n=42) desarrolló SG (NSG: n=13). Las únicas variables estadísticamente significativas en los tres momentos evaluados y que obtenían una buena área bajo la curva [AUROC (>0,70)] fueron la elevación de neutrófilos y procalcitonina y la disminución de bicarbonato. En el momento del ingreso la variable que mejor predecía SG fue la elevación de procalcitonina (AUROC: 0,919). Los factores de riesgo de SG (p < 0,05) fueron los antecedentes de cáncer, la inmunosupresión y/o cirugías de vías urinarias, la UO completa y los valores elevados en sangre de lactato y potasio y la disminución del bicarbonato en la gasometría venosa. La combinación potasio-lactato al ingreso predecía SG con una función de probabilidad de 0,805. CONCLUSIONES: Existe un perfil analítico, mantenido en el tiempo, característico de SG que permite la identificación precoz de los pacientes con UO subsidiarios de complicarse con SG


INTRODUCTION: Urosepsis is an underdiagnosed entity with high morbidity and mortality and significant associated costs. The delay in diagnosis leads to an increased risk of multiorgan failure and death. Although its prognosis is better than that of other sepsis, the mortality rate is 20 - 40%. OBJECTIVE: Describe the obstructive uropathy cases (OU) that are complicated by severe sepsis (SS) and identify early biomarkers of SS. MATERIAL AND METHODS: Observational and prospective study of 65 patients with urgent high OU. All patients were evaluated at three different times (0, 24 and 48 hours). An SS predictor model has been constructed and a multivariate risk analysis has been carried out. RESULTS: 64.61% (n=42) developed SS (NSS: n=13). The only statistically significant variables in the 3 moments evaluated and that obtained a good area under the curve [AUROC (>0.70)] were the elevation of neutrophils, procalcitonin, and decrease of bicarbonate. At the time of patient admission, the variable that best predicted SS was the elevation of procalcitonin (AUROC: 0.919). SS risk factors (p < 0.05) were the history of cancer, immunosuppression, and/or urinary tract surgeries, complete UO and high blood values of lactate, potassium and decrease of bicarbonate. The potassium-lactate combination on admission predicted SS with a probability function of 0.805. CONCLUSIONS: There is an analytical profile maintained over the time characteristic of SS that allows an early identification of patients with OU subsidiary of been complicated with SS


Assuntos
Humanos , Sepse/complicações , Obstrução Ureteral , Biomarcadores , Diagnóstico Precoce , Estudos Prospectivos , Gasometria , Fatores de Risco , Modelos Logísticos , Derivação Urinária , Terapia de Imunossupressão
3.
Arch. esp. urol. (Ed. impr.) ; 71(1): 34-39, ene.-feb. 2018. graf
Artigo em Espanhol | IBECS | ID: ibc-171825

RESUMO

Objetivo: La Ley 44/2003 de Ordenación de profesiones sanitarias creó el Consejo Nacional de Especialidades en Ciencias de la Salud y las Comisiones Nacionales de las Especialidades en Ciencias de la Salud. Métodos: Revisión de las principales normas legales implicadas en la Formación Especializada y papel de la Comisión Nacional de Especialidad. Discusión: La Ley 44/2003 regula la formación de los profesionales sanitarios y establece el procedimiento para la creación por la Comisión Nacional de Especialidad y su posterior aprobación y publicación en el BOE de los programas formativos de las especialidades. El acceso a la formación especializada se realizará con la convocatoria anual y de carácter nacional de examen MIR. El Ministerio de Sanidad fija los criterios de acreditación de los centros y unidades docentes, y la Comisión Nacional de Especialidad, como órgano asesor, emite un informe favorable o desfavorable sobre las nuevas peticiones de acreditación. El RD 183/2008 desarrolla la figura del tutor, la evaluación formativa junto con el Libro del Residente y cómo serán las rotaciones externas. Conclusiones: Para poder entender el sistema de formación en la especialidad de Urología debemos conocer las normas que lo regulan, siendo la más importante la 44/2003. La Comisión Nacional de Especialidad es un órgano consultivo del Ministerio, cuya función principal es la de elaborar el programa formativo de Urología y establecer los criterios de evaluación de los especialistas en formación (AU)


Objectives: 44/2003 Law involved the creation of the National Council of Specialties in Health Sciences and the National Commissions of the Specialties in Health Sciences. Methods: Analysis of the main laws implicated in Specialized Training and the role of the National Specialty Commission.Discussion: 44/2003 Law regulates the training of health professionals and establishes the procedure for the training programs creation by the National Specialty Commission and its later approval and publication in the BOE. Access to specialized training will be carried out with the annual and national MIR exam. The Health Ministry establishes the criteria for educational centers accreditation, and the National Specialty Commission issues a favorable or unfavorable report as advisor about new accreditation requests. 183/2008 RD develops the tutor figure, the formative evaluation through the Resident’s Book and how will be like the external rotations. Conclusions: to understand the Urology's specialty training system we must know the laws that regulate it, being the most important the 44/2003 Law. The National Specialty Commission is an advisory party of the Ministry, whose main function is to elaborate the Urology training program and to establish the evaluation criteria of the specialists in formation (AU)


Assuntos
Internato e Residência/legislação & jurisprudência , Acreditação de Programas , Urologia/educação , 35176 , Educação/legislação & jurisprudência , Espanha
4.
Arch Esp Urol ; 71(1): 34-39, 2018 Jan.
Artigo em Espanhol | MEDLINE | ID: mdl-29336330

RESUMO

OBJECTIVES: 44/2003 Law involved the creation of the National Council of Specialties in Health Sciences and the National Commissions of the Specialties in Health Sciences. METHODS: Analysis of the main laws implicated in Specialized Training and the role of the National Specialty Commission. DISCUSSION: 44/2003 Law regulates the training of health professionals and establishes the procedure for the training programs creation by the National Specialty Commission and its later approval and publication in the BOE. Access to specialized training will be carried out with the annual and national MIR exam. The Health Ministry establishes the criteria for educational centers accreditation, and the National Specialty Commission issues a favorable or unfavorable report as advisor about new accreditation requests. 183/2008 RD develops the tutor figure, the formative evaluation through the Resident's Book and how will be like the external rotations. CONCLUSIONS: to understand the Urology's specialty training system we must know the laws that regulate it, being the most important the 44/2003 Law. The National Specialty Commission is an advisory party of the Ministry, whose main function is to elaborate the Urology training program and to establish the evaluation criteria of the specialists in formation.


Assuntos
Urologia/educação , Espanha , Urologia/legislação & jurisprudência
5.
Arch. esp. urol. (Ed. impr.) ; 70(6): 570-578, jul.-ago. 2017. tab, graf
Artigo em Espanhol | IBECS | ID: ibc-164562

RESUMO

OBJETIVO: Analizar el tratamiento quirúrgico en el cáncer renal con trombo venoso a distintos niveles, así como las complicaciones perioperatorias y los diversos factores pronósticos relacionados a supervivencia global, cáncer específica y libre de enfermedad. MÉTODOS: Estudio descriptivo retrospectivo de 42 casos de cáncer renal con trombo venoso entre 2005 y 2015. El nivel alcanzado por el trombo se estableció según la clasificación de la Clínica Mayo. Las complicaciones postoperatorias se estadificaron según la clasificación de Clavien-Dindo. RESULTADOS: Predominio masculino con media de edad de 65,7 años. El 16,6% correspondieron a tumores con trombo de nivel II. En el 58,9% se realizó un abordaje subcostal. En 2 pacientes se estableció hipotermia con parada cardíaca y circulación extracorpórea. En 3 pacientes se realizó resección de lesiones metastásicas durante la nefrectomía radical. La necesidad de reintervención fue del 2,3% mientras que, la mortalidad perioperatoria fue del 4,7%. El 30% debutaron con metástasis al diagnóstico. Veinte pacientes progresaron a 15,5 meses (3-55). La supervivencia global fue de 60 meses. La mortalidad cáncer específica fue del 75%. La supervivencia libre de enfermedad fue del 30% a 55 meses. CONCLUSIONES: El tratamiento quirúrgico del cáncer renal con trombo venoso precisa un manejo multidisciplinar. La técnica quirúrgica seleccionada varía en función del nivel del trombo tumoral. El estadiaje tumoral es el factor pronóstico de mayor importancia. El nivel del trombo influye en el pronóstico, teniendo una supervivencia mayor aquellos pacientes con trombo confinado en vena renal (pT3a) frente a los tumores con trombo en aurícula (pT3c)


OBJECTIVES: To analyze surgery for renal cancer with venous thrombus at different levels, perioperative complications and prognostic factors associated to overall, cancer-specific and disease-free survival. MATERIAL AND METHODS: Retrospective analysis of 42 cases of renal cancer with venous thrombus performed between 2005 and 2015. The level reached by the thrombus was established according to the Mayo Clinic classification. Postoperative complications were staged according to Clavien-Dindo classification. RESULTS: Most frequent in males. Mean age 65.7 years. 16.6% were tumors with level II thrombus. Subcostal approach was performed in 58.9%. Extracorporeal circulation with cardiac arrest and hypothermia was established in 2 patients. Resection of metastatic disease was performed in 3 patients during radical nephrectomy. Reoperation was 2.3% while, perioperative mortality was 4.7%. 30% presented with metastases at diagnosis. Twenty patients progressed at 15.5 months (3-55). Overall survival was 60 months. The cancer-specific mortality was 75%. Disease-free survival was 30% at 55 months.CONCLUSIONS: Surgical treatment of renal cancer with venous thrombus requires a multidisciplinary management. The surgical technique varies according to the level reached by the venous thrombus. Tumor stage is the most important prognostic factor. Thrombus level influences prognosis, with longer survival for patients with tumor thrombus confined to the renal vein (pT3a) in comparison to tumors with thrombus in the atrium (pT3c)


Assuntos
Humanos , Masculino , Feminino , Pessoa de Meia-Idade , Idoso , Idoso de 80 Anos ou mais , Neoplasias Renais/cirurgia , Trombose Venosa/cirurgia , Nefrectomia/métodos , Trombectomia/métodos , Prognóstico , Detecção Precoce de Câncer/métodos , Estudos Retrospectivos , Complicações Pós-Operatórias/epidemiologia , Intervalo Livre de Doença
6.
Arch Esp Urol ; 70(6): 570-578, 2017 Jul.
Artigo em Espanhol | MEDLINE | ID: mdl-28678010

RESUMO

OBJECTIVES: To analyze surgery for renal cancer with venous thrombus at different levels, perioperative complications and prognostic factors associated to overall, cancer-specific and disease-free survival. MATERIAL AND METHODS: Retrospective analysis of 42 cases of renal cancer with venous thrombus performed between 2005 and 2015. The level reached by the thrombus was established according to the Mayo Clinic classification. Postoperative complications were staged according to Clavien-Dindo classification. RESULTS: Most frequent in males. Mean age 65.7 years. 16.6% were tumors with level II thrombus. Subcostal approach was performed in 58.9%. Extracorporeal circulation with cardiac arrest and hypothermia was established in 2 patients. Resection of metastatic disease was performed in 3 patients during radical nephrectomy. Reoperation was 2.3% while, perioperative mortality was 4.7%. 30% presented with metastases at diagnosis. Twenty patients progressed at 15.5 months (3-55). Overall survival was 60 months. The cancer-specific mortality was 75%. Disease-free survival was 30% at 55 months. CONCLUSIONS: Surgical treatment of renal cancer with venous thrombus requires a multidisciplinary management. The surgical technique varies according to the level reached by the venous thrombus. Tumor stage is the most important prognostic factor. Thrombus level influences prognosis, with longer survival for patients with tumor thrombus confined to the renal vein (pT3a) in comparison to tumors with thrombus in the atrium (pT3c).


Assuntos
Carcinoma de Células Renais/secundário , Carcinoma de Células Renais/cirurgia , Neoplasias Renais/patologia , Neoplasias Renais/cirurgia , Células Neoplásicas Circulantes , Idoso , Intervalo Livre de Doença , Feminino , Veias Hepáticas , Humanos , Masculino , Prognóstico , Veias Renais , Estudos Retrospectivos , Análise de Sobrevida , Veia Cava Inferior
9.
Arch Esp Urol ; 68(7): 602-8, 2015 Sep.
Artigo em Espanhol | MEDLINE | ID: mdl-26331396

RESUMO

OBJECTIVES: Small cell carcinoma of the bladder shows low incidence and poor survival; thus, treatment algorithms based on randomized studies are unavailable. The aim of the present study is to review our case series. METHODS: Observational retrospective study of 10 patients diagnosed with small cell carcinoma of the bladder between 2006 and 2013. RESULTS: Mean age was 65.7 years; There was only one female in the cohort. In all cases hematuria was the fist symptom. 4 cases presented high-grade papillary urothelial carcinoma with small cell carcinoma. Radical cystectomy was performed in 40% patients, in combination with chemotherapy, radiotherapy or both. Median survival was 330 days (IC 95%: 40.757- 619.243) and only one patient showed complete response. CONCLUSIONS: Even when small cell carcinoma of the bladder is a low incidence tumor, its prognosis is worse than that of urothelial carcinoma. Although further randomized studies are needed to best define treatment, this study shows that survival at local stages is optimized by neoadjuvant chemotherapy, followed by radical resection, as the literature suggests.


Assuntos
Carcinoma de Células Pequenas , Neoplasias da Bexiga Urinária , Idoso , Carcinoma de Células Pequenas/diagnóstico , Carcinoma de Células Pequenas/terapia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Neoplasias da Bexiga Urinária/diagnóstico , Neoplasias da Bexiga Urinária/terapia
10.
Arch. esp. urol. (Ed. impr.) ; 68(7): 602-608, sept. 2015. tab, graf
Artigo em Espanhol | IBECS | ID: ibc-144572

RESUMO

OBJETIVO: El carcinoma vesical de células pequeñas presenta una baja incidencia y escasa supervivencia, por lo que no existen esquemas terapéuticos basados en estudios randomizados. Nos planteamos como objetivo revisar nuestra casuística. MÉTODOS: Estudio observacional retrospectivo de 10 pacientes diagnosticados de carcinoma de células pequeñas entre 2006 y 2013. RESULTADOS: La edad media fue de 65,7 años y sólo se presentó en una mujer de los 10 pacientes. Se relacionó en su totalidad con antecedentes de tabaquismo, siendo la forma de presentación la hematuria. 4 casos presentaban carcinoma urotelial de alto grado junto con el componente microcítico. Se realizó cistectomía radical en el 40% de los pacientes, recibiendo además tratamiento con quimioterapia, radioterapia o ambos. La mediana del tiempo de supervivencia fue de 330 días (IC 95%: 40,757 - 619,243). Sólo en un caso obtuvimos respuesta completa. CONCLUSIONES: El carcinoma de células pequeñas de vejiga es un tumor con baja incidencia pero de peor pronóstico que los tumores uroteliales. Aunque se necesiten más estudios randomizados para definir el mejor tratamiento, y nuestra casuística sea limitada, se ha publicado que los mejores resultados en cuanto a supervivencia en los estadios localizados se consiguen con quimioterapia neoayuvante seguida de cirugía radical


OBJECTIVES: Small cell carcinoma of the bladder shows low incidence and poor survival; thus, treatment algorithms based on randomized studies are unavailable. The aim of the present study is to review our case series. METHODS: Observational retrospective study of 10 patients diagnosed with small cell carcinoma of the bladder between 2006 and 2013. RESULTS: Mean age was 65.7 years; There was only one female in the cohort. In all cases hematuria was the fist symptom. 4 cases presented high-grade papillary urothelial carcinoma with small cell carcinoma. Radical cystectomy was performed in 40% patients, in combination with chemotherapy, radiotherapy or both. Median survival was 330 days (IC 95%: 40.757- 619.243) and only one patient showed complete response. CONCLUSIONS: Even when small cell carcinoma of the bladder is a low incidence tumor, its prognosis is worse than that of urothelial carcinoma. Although further randomized studies are needed to best define treatment, this study shows that survival at local stages is optimized by neoadjuvant chemotherapy, followed by radical resection, as the literature suggests


Assuntos
Feminino , Humanos , Masculino , Carcinoma de Células Pequenas/diagnóstico , Carcinoma de Células Pequenas/patologia , Bexiga Urinária/citologia , Bexiga Urinária/lesões , Neoplasias da Bexiga Urinária/tratamento farmacológico , Neoplasias da Bexiga Urinária/radioterapia , Cistectomia/métodos , Cistectomia , Carcinoma de Células de Transição/patologia , Estudo Observacional , Carcinoma de Células Pequenas/complicações , Carcinoma de Células Pequenas/metabolismo , Bexiga Urinária/anormalidades , Bexiga Urinária/metabolismo , Neoplasias da Bexiga Urinária/reabilitação , Neoplasias da Bexiga Urinária/terapia , Cistectomia/instrumentação , Cistectomia/normas , Carcinoma de Células de Transição/metabolismo , Estudos Retrospectivos
11.
Arch Esp Urol ; 67(8): 704-7, 2014 Oct.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-25306989

RESUMO

OBJECTIVE: Haemangiopericytoma is an uncommon perivascular tumor that occurs more frequently in soft tissues and is extremely rare in the kidney. METHODS: We report two cases: The first one is the case of a 57-year-old man with bilateral metastatic renal haemangiopericytoma which appeared 18 years after removal of a meningeal haemangiopericytoma. The second is a 29-year-old woman with a primary kidney haemangiopericytoma that was casually found in a nephrectomy piece. RESULTS: In the first case, radical left nephrectomy and right renal mass radiofrequency ablation were performed. The patient had an uneventful postoperatory recovery. He remained disease-free 22 months after surgery but two new lesions appeared that were treated with radiofrequency ablation. The second case was a casual finding, a small tumor that had been totally resected. CONCLUSIONS: Haemangiopericytoma is a rare tumor with an uncertain clinical behaviour. Long-term follow up is important as local recurrences and metastases can develop years after initial treatment.


Assuntos
Hemangiopericitoma , Neoplasias Renais , Adulto , Feminino , Hemangiopericitoma/diagnóstico , Hemangiopericitoma/cirurgia , Humanos , Neoplasias Renais/diagnóstico , Neoplasias Renais/cirurgia , Masculino , Pessoa de Meia-Idade , Recidiva Local de Neoplasia , Nefrectomia
12.
Arch. esp. urol. (Ed. impr.) ; 67(8): 704-707, oct. 2014. ilus
Artigo em Espanhol | IBECS | ID: ibc-129484

RESUMO

OBJETIVO: El hemangiopericitoma es un raro tumor perivascular que aparece sobre todo en los tejidos blandos y que es muy inusual en el riñón. MÉTODO: Se describen dos casos. Caso 1: Varón de 57 años con un hemangiopericitoma renal bilateral metastásico que tuvo lugar 18 años después de la exéresis de un hemangiopericitoma meníngeo. Caso 2: Mujer de 29 con un hemangiopericitoma renal primario hallado de forma casual en la pieza de nefrectomía por una pionefrosis. RESULTADOS: En el primer caso se realizó una nefrectomía radical izquierda y ablación con rediofrecuencia de la masa renal derecha. El postoperatorio cursó sin complicaciones y no hubo signos de enfermedad durante 22 meses, hasta que aparecieron nuevas lesiones en riñón derecho, que fueron tratadas nuevamente con radiofrecuencia. El segundo caso fue un tumor de hallazgo casual, de escaso tamaño y totalmente resecado en la pieza quirúrgica. CONCLUSIONES: El hemangiopericitoma es un tumor raro y de comportamiento incierto, que requiere un seguimiento a largo plazo. La recidiva local y las metástasis pueden aparecer años después del tratamiento del tumor primario


OBJECTIVE: Haemangiopericytoma is an uncommon perivascular tumor that occurs more frequently in soft tissues and is extremely rare in the kidney. METHODS: We report two cases: The first one is the case of a 57-year-old man with bilateral metastatic renal haemangiopericytoma which appeared 18 years after removal of a meningeal haemangiopericytoma. The second is a 29-year-old woman with a primary kidney haemangiopericytoma that was casually found in a nephrectomy piece. RESULTS: In the first case, radical left nephrectomy and right renal mass radiofrequency ablation were performed. The patient had an uneventful postoperatory recovery. He remained disease-free 22 months after surgery but two new lesions appeared that were treated with radiofrequency ablation. The second case was a casual finding, a small tumor that had been totally resected. CONCLUSIONS: Haemangiopericytoma is a rare tumor with an uncertain clinical behaviour. Long-term follow up is important as local recurrences and metastases can develop years after initial treatment


Assuntos
Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Hemangiopericitoma/diagnóstico , Hemangiopericitoma/radioterapia , Hemangiopericitoma/cirurgia , Ablação por Cateter/métodos , Tratamento por Radiofrequência Pulsada , Hemangiopericitoma , Neoplasias de Células Epitelioides Perivasculares/complicações , Nefrectomia/métodos , Pionefrose/complicações , Recidiva Local de Neoplasia/prevenção & controle , Recidiva
13.
Arch Esp Urol ; 67(4): 323-30, 2014 May.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-24892393

RESUMO

OBJECTIVES: To determine the prevalence of urinary incontinence (UI) before pregnancy, in the third trimester and postpartum. To analyze its influence on quality of life and associated potential risk factors and the efficacy of pelvic floor exercises. METHODS: Prospective study in 413 pregnant women. The modified ICIQ-SF incontinence questionnaire was given to the pregnant women at the end of the third quarter. This questionnaire was administered by telephone at 3 and 6 months postpartum. The influence of several risk factors for UI in pregnancy and postpartum were analyzed. Patients with persistent UI at 6 months postpartum were trained to do pelvic floor exercises. RESULTS: Patients with UI before pregnancy were excluded from the study. UI in the third trimester was 31%. Analyzed risk factors did not condition a higher percentage of UI. Prevalence of UI was 11.3% at 3 months postpartum and 6.9% at 6 months. 70% of the incontinent patients already had it during pregnancy and it appeared de novo post-delivery in 30% of the patients. Prevalence of UI after delivery was higher in women with UI in pregnancy and lower in caesarean cases. Most women improved with pelvic floor exercises. CONCLUSIONS: Analysed risk factors did not significantly increase UI in pregnancy. Prevalence of UI after delivery is higher in women with UI in pregnancy and lower in caesarean cases. Postpartum pelvic floor exercises for three months in patients with persistent stress UI at 6 months postpartum clearly improved the degree of continence.


Assuntos
Terapia por Exercício/métodos , Diafragma da Pelve , Incontinência Urinária/etiologia , Adulto , Feminino , Humanos , Período Pós-Parto , Gravidez , Prevalência , Fatores de Risco , Incontinência Urinária/epidemiologia
14.
Arch. esp. urol. (Ed. impr.) ; 67(4): 323-330, mayo 2014. tab
Artigo em Espanhol | IBECS | ID: ibc-122089

RESUMO

OBJETIVO: Determinar la prevalencia de incontinencia urinaria (IU) previa a la gestación, en el tercer trimestre y en el postparto. Analizar su influencia en la calidad de vida, los posibles factores de riesgo y la eficacia de los ejercicios del suelo pélvico. MÉTODOS: Estudio prospectivo a 413 gestantes. Se entregó el cuestionario de incontinencia ICIQ-SF modificado a las gestantes al final del tercer trimestre y a los 3 y 6 meses postparto. Se analizó la influencia de varios factores de riesgo de IU en el embarazo y en el postparto. Las pacientes con persistencia de IU a los 6 meses del parto fueron instruidas para realizar ejercicios de suelo pélvico. RESULTADOS: Las pacientes con IU previa a la gestación fueron excluidas. La prevalencia de incontinencia en el tercer trimestre en gestantes fue del 31%. Ningún factor de riesgo condicionó un mayor porcentaje de IU. La prevalencia de IU fue de 11.3 % a los tres meses del parto y del 6.9% a los 6 meses. De las pacientes incontinentes un 70% ya la sufría en el embarazo y en el 30% apareció de novo tras el parto. El porcentaje de IU postparto fue más elevado en mujeres con IU en la gestación y más bajo en aquellas con cesárea. La mayoría de las mujeres mejoraron con ejercicios de suelo pélvico. CONCLUSIONES: Ningún factor de riesgo aumenta el riesgo de IU en gestantes de forma significativa. La prevalencia de IU tras el parto es mayor en aquellas mujeres con IU en el embarazo y más baja en aquellas con cesárea. La mayoría de las puerperas mejoraron con ejercicios de suelo pélvico


OBJECTIVES: To determine the prevalence of urinary incontinence (UI) before pregnancy, in the third trimester and postpartum. To analyze its influence on quality of life and associated potential risk factors and the efficacy of pelvic floor exercises. METHODS: Prospective study in 413 pregnant women. The modified ICIQ-SF incontinence questionnaire was given to the pregnant women at the end of the third quarter. This questionnaire was administered by telephone at 3 and 6 months postpartum. The influence of several risk factors for UI in pregnancy and postpartum were analyzed. Patients with persistent UI at 6 months postpartum were trained to do pelvic floor exercises. RESULTS: Patients with UI before pregnancy were excluded from the study. UI in the third trimester was 31%. Analyzed risk factors did not condition a higher percentage of UI. Prevalence of UI was 11.3% at 3 months postpartum and 6.9% at 6 months. 70% of the incontinent patients already had it during pregnancy and it appeared de novo post-delivery in 30% of the patients. Prevalence of UI after delivery was higher in women with UI in pregnancy and lower in caesarean cases. Most women improved with pelvic floor exercises. CONCLUSIONS: Analysed risk factors did not significantly increase UI in pregnancy. Prevalence of UI after delivery is higher in women with UI in pregnancy and lower in caesarean cases. Postpartum pelvic floor exercises for three months in patients with persistent stress UI at 6 months postpartum clearly improved the degree of continence


Assuntos
Humanos , Incontinência Urinária/epidemiologia , Distúrbios do Assoalho Pélvico/reabilitação , Técnicas de Exercício e de Movimento/métodos , Complicações na Gravidez/epidemiologia , Complicações do Trabalho de Parto/epidemiologia , Fatores de Risco , Qualidade de Vida , Cesárea/estatística & dados numéricos
15.
Rev. chil. urol ; 79(1): 24-29, 2014. ilus, tab, graf
Artigo em Espanhol | LILACS | ID: lil-783414

RESUMO

La embolización renal es un procedimiento intervencionista, cuyas aplicaciones terapéuticas han variado a lo largo del tiempo. Realizamos una revisión retrospectiva de 48 embolizaciones, analizando las causas y complicaciones asociadas a esta técnica. Nuestra indicación principal fue la embolización prequirúrgica de tumores renales de gran tamaño, aunque la indicación de mayor relevancia clínica actual es el tratamiento conservador de fístulas arterio-venosas iatrogénicas, angiomiolipomas o traumatismos renales con sangrado activo. La complicación menor más frecuente es el síndrome post-embolización (52.8 por ciento), situación que remite fácilmente con tratamiento médico. Como complicaciones mayores destacan la sepsis y la migración de material embolígeno, ambos muy poco frecuentes en nuestra serie...


Renal embolization is an interventional procedure, whose therapeutic applications have varied over time. We conducted a retrospective review of 48 embolizations, analyzing the causes and complications associated with this technique. Our main indication was the preoperative embolization of large renal tumors, although the most relevant indication today is the conservative treatment of iatrogenic arteriovenous fistula, angiomyolipomas or renal trauma with active bleeding. The most common minor complication is post-embolization syndrome (52.8 percent), a situation that is easily managed with medical treatment. Major complications include sepsis and migration of embolic material and both are very rare in our series...


Assuntos
Humanos , Masculino , Feminino , Adolescente , Adulto , Pessoa de Meia-Idade , Adulto Jovem , Embolização Terapêutica , Fístula Arteriovenosa/terapia , Neoplasias Renais/terapia , Artéria Renal , Cuidados Pré-Operatórios , Embolização Terapêutica/efeitos adversos , Estudos Retrospectivos
16.
Arch Esp Urol ; 66(9): 873-7, 2013 Nov.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-24231298

RESUMO

OBJECTIVE: To report one case of advanced fibrous pseudotumour. METHODS: A 34-year-old patient presented with a painless lump on the right side of the scrotum. Examination revealed a hard tissue thickening attached to the tail and body of the right epididymis. The results of the ultrasound study were not clear and multiple differential diagnosis were considered. The lesion was surgically removed by partial right epididymectomy and resection of the affected tunica vaginalis and ductus deferens for anatomopathological study. RESULTS: The histopathological study revealed an evolved fibrous pseudotumour with bone metaplasia. CONCLUSION: Fibrous pseudotumour is a benign paratesticular lesion that grows slowly and painlessly. It is usually diagnosed by chance or in associated processes such as hydrocele. Differential diagnosis with malignant tumors avoids unnecessary radical treatment.


Assuntos
Epididimo/patologia , Epididimo/cirurgia , Genitália Masculina/patologia , Genitália Masculina/cirurgia , Granuloma de Células Plasmáticas/patologia , Granuloma de Células Plasmáticas/cirurgia , Glândulas Seminais/patologia , Glândulas Seminais/cirurgia , Procedimentos Cirúrgicos Urológicos Masculinos/métodos , Adulto , Humanos , Imuno-Histoquímica , Masculino , Escroto/patologia , Escroto/cirurgia
17.
Arch. esp. urol. (Ed. impr.) ; 66(9): 873-877, nov. 2013. ilus
Artigo em Espanhol | IBECS | ID: ibc-116968

RESUMO

OBJETIVO: Presentamos un caso evolucionado de Pseudotumor fibroso. MÉTODOS: Varón de 34 años que consulta por bultoma escrotal derecho indoloro presentando a la exploración un engrosamiento de consistencia indurada fusionado a la cola y el cuerpo de epidídimo derecho. El estudio ecográfico no fue aclaratorio planteando múltiples diagnósticos diferenciales. Se realizó exéresis de la lesión precisando una epididimectomía parcial derecha y resección de la túnica vaginal y el conducto deferente afectados para su estudio anatomopatológico. RESULTADOS: El estudio histopatológico de la pieza quirúrgica correspondía a un pseudotumor fibroso evolucionado, con metaplasia ósea. CONCLUSIÓN: El pseudotumor fibroso es una lesión paratesticular benigna, de crecimiento lento e indoloro. El diagnóstico suele ser por hallazgo casual o por procesos asociados como el hidrocele. El diagnóstico diferencial con los tumores malignos evita tratamientos radicales innecesarios (AU)


OBJECTIVE: To report one case of advanced fibrous pseudotumour. METHODS: A 34-year-old patient presented with a painless lump on the right side of the scrotum. Examination revealed a hard tissue thickening attached to the tail and body of the right epididymis. The results of the ultrasound study were not clear and multiple differential diagnosis were considered. The lesion was surgically removed by partial right epididymectomy and resection of the affected tunica vaginalis and ductus deferens for anatomopathological study. RESULTS: The histopathological study revealed an evolved fibrous pseudotumour with bone metaplasia. CONCLUSION: Fibrous pseudotumour is a benign paratesticular lesion that grows slowly and painlessly. It is usually diagnosed by chance or in associated processes such as hydrocele. Differential diagnosis with malignant tumors avoids unnecessary radical treatment (AU)


Assuntos
Humanos , Masculino , Adulto , Fibroma/diagnóstico , Neoplasias Testiculares/diagnóstico , Diagnóstico Diferencial , Escroto/patologia , Epididimo/patologia , Glândulas Seminais/patologia
18.
Arch Esp Urol ; 65(4): 467-75, 2012 May.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-22619138

RESUMO

OBJECTIVES: Testicular cancer represents about 1% of malignant tumors in men. Of these tumors 95% are germ cell tumors (GCTs), which have a maximum incidence between the second and third decades of life. Our objective was to carry out a retrospective analysis of testicular tumor cases that had been diagnosed in our Health Area between the years 2000 and 2010. METHODS: We performed a retrospective descriptive study between the years 2000 and 2010 analyzing 43 patients treated for testicular cancer, including in the analysis tumor incidence, the patient's age, clinic attended, patient's time until appointment, presence of tumor markers, patient's time before treatment, use of testicular prostheses, histological type and their typical characteristics, oncological treatment, tumor progression and mortality rate. RESULTS: We found an incidence of 4-5 cases/100,000 population/year in our Health Area. Two-thirds of the cases were detected in Stage I, and 100% of these cases showed complete remission. Among those with higher stage tumors, two out of three patients were cured after chemotherapy. For the remaining one-third, rescue treatments managed to achieve a remission rate of 66%. Mortality was low and was linked to lymphoma or metastatic dissemination. CONCLUSION: The trend towards early diagnosis with detection during the initial cancer stages, together with current chemotherapy protocols, enables a high cure rate for testicular cancer. Mortality in our series was associated with primary or secondary lymphomas.


Assuntos
Neoplasias Embrionárias de Células Germinativas , Neoplasias Testiculares , Adulto , Biomarcadores Tumorais/sangue , Humanos , Incidência , Masculino , Pessoa de Meia-Idade , Neoplasias Embrionárias de Células Germinativas/epidemiologia , Neoplasias Embrionárias de Células Germinativas/patologia , Neoplasias Embrionárias de Células Germinativas/terapia , Estudos Retrospectivos , Espanha/epidemiologia , Neoplasias Testiculares/epidemiologia , Neoplasias Testiculares/patologia , Neoplasias Testiculares/terapia , Carga Tumoral , Adulto Jovem
19.
Arch. esp. urol. (Ed. impr.) ; 65(4): 467-475, mayo 2012. tab, graf
Artigo em Espanhol | IBECS | ID: ibc-99381

RESUMO

OBJETIVO: El cáncer de testículo representa alrededor del 1% de los tumores malignos en el varón. El 95% corresponde a tumores germinales (TTG) cuya máxima incidencia tiene lugar entre la 2ª y 3ª década de la vida. Nuestro objetivo es realizar un análisis retrospectivo de los tumores testiculares diagnosticados en nuestra Área de Salud entre los años 2000 y 2010. MÉTODOS: Estudio descriptivo retrospectivo de los pacientes con cáncer testicular entre los años 2000 y 2010, analizándose un total de 43 pacientes, con evaluación de la incidencia, edad, presentación clínica, tiempo hasta la consulta, marcadores tumorales, tiempo hasta el tratamiento, solicitud de prótesis testicular, tipo histológico y características anatomopatológicas propias, tratamiento oncológico, progresión tumoral y mortalidad. RESULTADOS: En nuestro área de salud encontramos una incidencia de 4-5 casos-/100000habitantes/año. Las dos terceras partes de los casos se detectaron en Estadio I, consiguiendo remisión completa en el 100%. En Estadios superiores hay curación en 2 de cada 3 pacientes tras la quimioterapia y en el tercio restante, los tratamientos de rescate consiguen la remisión en el 66%. La mortalidad es baja y asociada a afectación por Linfoma o a diseminación metastásica. CONCLUSIÓN: La tendencia al diagnóstico precoz con detección en estadios iniciales, asociado a los actuales protocolos de quimioterapia, permiten altos índices de curación en el cáncer testicular. La mortalidad en nuestra serie se asocia mayoritariamente a afectación por Linfoma primario o secundario(AU)


OBJECTIVES: Testicular cancer represents about 1% of malignant tumors in men. Of these tumors 95% are germ cell tumors (GCTs), which have a maximum incidence between the second and third decades of life. Our objective was to carry out a retrospective analysis of testicular tumor cases that had been diagnosed in our Health Area between the years 2000 and 2010. METHODS: We performed a retrospective descriptive study between the years 2000 and 2010 analyzing 43 patients treated for testicular cancer, including in the analysis tumor incidence, the patient’s age, clinic attended, patient’s time until appointment, presence of tumor markers, patient’s time before treatment, use of testicular prostheses, histological type and their typical characteristics, oncological treatment, tumor progression and mortality rate. RESULTS: We found an incidence of 4-5 cases/100,000 population/year in our Health Area. Two-thirds of the cases were detected in Stage I, and 100% of these cases showed complete remission. Among those with higher stage tumors, two out of three patients were cured after chemotherapy. For the remaining one-third, rescue treatments managed to achieve a remission rate of 66%. Mortality was low and was linked to lymphoma or metastatic dissemination. CONCLUSION: The trend towards early diagnosis with detection during the initial cancer stages, together with current chemotherapy protocols, enables a high cure rate for testicular cancer. Mortality in our series was associated with primary or secondary lymphomas(AU)


Assuntos
Humanos , Masculino , Neoplasias Testiculares/epidemiologia , Neoplasias Embrionárias de Células Germinativas/epidemiologia , Estudos Retrospectivos , Distribuição por Idade , Detecção Precoce de Câncer
20.
Arch. esp. urol. (Ed. impr.) ; 64(7): 629-631, sept. 2011. ilus
Artigo em Espanhol | IBECS | ID: ibc-94335

RESUMO

OBJETIVO: Revisar la presentación, diagnóstico y tratamiento de una entidad poco frecuente como los aneurismas de la arteria renal.MÉTODOS: Presentamos el caso de un paciente monorreno con un aneurisma renal calcificado sintomático.RESULTADOS: Los aneurismas de la arteria renal pueden provocar hipertensión, hematuria, dolor en flanco, o ser totalmente asintomáticos. Las causas más frecuentes son laarteriosclerosis y la displasia fibromuscular y el diagnóstico se basa en la tomografía computerizada y en la angiografía. El tratamiento puede ser quirúrgico, endovascular o expectante.CONCLUSIONES: Los aneurismas de la arteria renal son una patología sobre la que, por su baja prevalencia, no existen pautas claras de actuación. El número de casos diagnosticados ha aumentado en las últimas décadas y el tratamiento endovascular se muestra como una buena opción(AU)


OBJECTIVE: To review presentation, diagnosis and treatment of renal artery aneurysms, a very uncommon disease.METHODS: We report the case of a male with a calcified renal artery aneurysm in a solitary kidney.RESULTS: Symptomatic effects may be hypertension, hematuria or flank pain. Arteriosclerosis and medial dysplasia are the most frequent causes and diagnosis is based on CT scan and angiography.CONCLUSIONS: The renal artery aneurysm is a disease with low prevalence and there is no clear protocol for management. The number of cases has increased over the last decades and endovasculrar treatment is a good therapeutic option(AU)


Assuntos
Humanos , Masculino , Aneurisma/complicações , Aneurisma/diagnóstico , Hipertensão/complicações , Hematúria/complicações , Dor no Flanco/complicações , Dor no Flanco/etiologia , Displasia Fibromuscular/complicações , Displasia Fibromuscular/diagnóstico , Procedimentos Endovasculares/métodos , Procedimentos Endovasculares/tendências , Artéria Renal/patologia , Dor no Flanco/diagnóstico , Arteriosclerose/complicações , Arteriosclerose/diagnóstico
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