Non-similar bioconvective analysis of magnetized hybrid nanofluid (Ag + TiO2) flow over exponential stretching surface.

Scientists have studied fluid flow over a stretching sheet to explore its potential applications in industries. This study investigates the exponential stretching flow of a bioconvective magnetohydrodynamic (MHD) hybrid nanofluid in porous medium taking into consideration thermal radiations, heat generation, chemical reaction, porosity, and dissipation. Moreover, microorganisms are present in the fluid, so the fluid is more stable, which is crucial in biotechnology, biomicrosystems, and bio-nano coolant systems. Silver and titanium dioxide in a water-based medium are the prototypical nanoparticles. The present study involves a transformation of the governing system into a set of dimensionless, coupled and nonlinear partial differential equations (PDEs) using nonsimilar techniques. The local non-similarity (LNS) technique is used to truncate these equations to ordinary differential equations (ODEs). This technique is also used to estimate transformed equations numerically until the second level of truncation takes place via the bvp4c algorithm, which is a built-in MATLAB solver. Furthermore, tables are provided that presents the drag coefficients, Nusselt numbers, Sherwood numbers, and densities of motile microorganisms. Results show a negative correlation between the velocity and the magnetic field parameter as well as the porosity parameter, as evidenced by a decrease in velocity corresponds to rises in these parameters. The temperature distribution exhibits a positive correlation with the rising values of both radiation parameter and Eckert number. The concentration profiles also exhibit a negative correlation with the increasing values of Lewis and bioconvection Lewis number, chemical reaction parameter, Peclet number and the differences in microbial concentration. This study will improve the future research on hybrid nanofluid regarding industrial applications. There haven't been any previous publications that have investigated the use of this model with the local non-similarity method. The main objective of this article is to enhance the heat transfer performance in a hybrid nanofluid.

Spherical Hybrid Nanoparticles for Homann Stagnation-Point Flow in Porous Media via Homotopy Analysis Method.

Non-axisymmetric stagnant-point flows for flat plates in porous media containing spherical Cu-Al2O3-H2O nanoparticles are studied using the homotopy analysis method (HAM). The governing equations are transformed into three coupled non-linear ordinary differential equations through similarity transformations. A large degree of freedom is provided by HAM when selecting auxiliary linear operators. By transforming nonlinear coupled ordinary differential equations with variable coefficients into linear ordinary differential equations with constant coefficients, nonlinear coupled ordinary differential equations can be solved. Over the entire domain, these equations can be solved approximately analytically. The analysis involves a discussion of the impact of many physical parameters generated in the proposed model. The results have shown that skin friction coefficients of Cfx and Cfy increase with volume fraction of hybrid nanofluid and the coefficient of permeability increasing. For the axisymmetric case of γ = 0, when volume fraction, φ, φ1, φ2 = 0, 5%, 10%, 20%, Cfx = Cfy = 1.33634, 1.51918, 1.73905, 2.33449, it can be found that the wall shear stress values increase by 13.68%, 30.14%, and 74.69%, respectively. In response to an increase in hybrid nanofluid volume fractions, local Nusselt numbers Nux increase. Nux decrease and change clearly with the coefficient of permeability increasing in the range of γ < 0; the values of Nux are less affected in the range of γ > 0.

Thermal Analysis of Radiative Darcy-Forchheimer Nanofluid Flow Across an Inclined Stretching Surface.

Nanofluids have unique features that make them potentially valuable in a variety of medicinal, technical, and industrial sectors. The widespread applications of nanotechnology in modern science have prompted researchers to study nanofluid models from different perspectives. The objective of the current research is to study the flow of non-Newtonian nanofluid over an inclined stretching surface immersed in porous media by employing the Darcy-Forchheimer model. Both titanium oxide (TiO2) and aluminum oxide (Al2O3) are nanoparticles which can be found in blood (based fluid). The consequences of viscous dissipation, thermal radiations, and heat generation are also incorporated. Boundary layer approximations are employed to model the governing system of partial differential equations (PDEs). The governing PDEs with their associated boundary conditions are further altered to a dimensionless form by employing appropriate transformations. The results of the transformed model are collected using local non-similarity approach up to the second level of truncation in association with the built-in finite difference code in MATLAB (bvp4c). Additionally, the impacts of emerging factors on the fluid flow and thermal transport features of the considered flow problem are displayed and analyzed in graphical forms after achieving good agreement between accomplished computational results and published ones. Numerical variations in drag coefficient and Nusselt number are elaborated through the tables. It has been perceived that the enhancement in Casson fluid parameter diminishes the velocity profile. Moreover, it is noted that the porosity parameter and Lorentz's forces reinforce the resulting frictional factor at the inclined stretching surface.

[The expression of peroxiredoxin II in hepatocellular carcinoma and its significance].

OBJECTIVE: To evaluate the mRNA and protein expressions of peroxiredoxin II (PrxII) in hepatocellular carcinoma (HCC) and their significance. METHODS: HCC was induced by aflatoxin B1 (AFB1) in 6 tree shrews (Tupaia belangeri chinensis). The expression levels of PrxII mRNA and protein were detected by reverse transcriptase polymerase chain reaction (RT-PCR) and Western blot on HCC tissues and on their surrounding liver tissues (para-HCC). Biopsied liver tissues were taken before the HCC induction (pre-HCC) from the same animals and from a group of blank controlled animals that served as controls. Liver biopsy specimens from 18 cases of human HCC and from 17 healthy human volunteers were studied using the same methods. RESULTS: The mRNA and protein expressions of PrxII in tree shrew HCC tissues were significantly higher than those in para-HCC and pre-HCC tissues, and also higher than those in the liver tissues from the control animals (all P < 0.05). The expression levels of PrxII mRNA and protein in human HCC tissues were also significantly higher than those in their para-HCC tissues and in the human normal liver tissues (P < 0.05). CONCLUSION: PrxII might play an important role in hepatocarcinogenesis and might be used as a molecular target for HCC prevention and treatment.