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1.
Adv Mater ; 36(23): e2313198, 2024 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-38413013

RESUMO

Shape morphing in bistable kirigami enables remarkable functionalities appealing to a diverse range of applications across the spectrum of length scale. At the core of their shape shifting lies the architecture of their repeating unit, where highly deformable slits and quasi-rigid rotating units often exhibit multiple symmetries that confer isotropic deployment obeying uniform scaling transformation. In this work, symmetry breaking in bistable kirigami is investigated to access geometric frustration and anisotropic morphing, enabling arbitrarily scaled deployment in planar and spatial bistable domains. With an analysis on their symmetry properties complemented by a systematic investigation integrating semi-analytical derivations, numerical simulations, and experiments on elastic kirigami sheets, this work unveils the fundamental relations between slit symmetry, geometric frustration, and anisotropic bistable deployment. Furthermore, asymmetric kirigami units are leveraged in planar and flat-to-3D demonstrations to showcase the pivotal role of shear deformation in achieving target shapes and functions so far unattainable with uniformly stretchable kirigami. The insights provided in this work unveil the role of slit symmetry breaking in controlling the anisotropic bistable deployment of soft kirigami metamaterials, enriching the range of achievable functionalities for applications spanning deployable space structures, wearable technologies, and soft machines.

2.
Am J Otolaryngol ; 32(1): 52-4, 2011.
Artigo em Inglês | MEDLINE | ID: mdl-20022666

RESUMO

Osteochondromas are the most common benign bone tumor, most commonly found in the ends of long bones; however, they rarely involve facial bones, particularly the mandible. Osteochondromas involving the coronoid process have rarely been reported in the literature but pose a diagnostic dilemma. When large enough, osteochondromas of the mandibular coronoid process can form a joint with the zygomatic arch (Jacob's disease). This pseudoarticulation results in restricted jaw motion, which can clinically be mistaken for temporomandibular joint dysfunction. We report a case of a 39-year-old man with chronic restricted jaw motion undiagnosed for several years.


Assuntos
Neoplasias Maxilomandibulares/diagnóstico , Osteocondroma/diagnóstico , Adulto , Humanos , Neoplasias Maxilomandibulares/fisiopatologia , Neoplasias Maxilomandibulares/cirurgia , Imageamento por Ressonância Magnética , Masculino , Osteocondroma/fisiopatologia , Osteocondroma/cirurgia , Amplitude de Movimento Articular , Tomografia Computadorizada por Raios X
3.
J Neuroimaging ; 21(2): 184-7, 2011 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-19490401

RESUMO

The hallmark radiological finding in metastatic brain disease is multiple enhancing lesions. We report a case of metastatic lung cancer to the brain with a lack of contrast enhancement. We believe that this unusual finding is due to inadvertent "treatment" of the metastases with the antiangiogenic agent bevacizumab (Avastin).


Assuntos
Neoplasias Encefálicas/secundário , Neoplasias Pulmonares/patologia , Imageamento por Ressonância Magnética , Neoplasias das Glândulas Suprarrenais/tratamento farmacológico , Neoplasias das Glândulas Suprarrenais/secundário , Idoso , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Neoplasias Ósseas/tratamento farmacológico , Neoplasias Ósseas/secundário , Neoplasias Encefálicas/tratamento farmacológico , Meios de Contraste , Progressão da Doença , Humanos , Neoplasias Pulmonares/tratamento farmacológico , Masculino
4.
Neuroradiology ; 52(6): 549-53, 2010 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-20440485

RESUMO

Although neuroblastoma is a common childhood malignancy, which frequently metastasizes, involvement of the facial bones and paranasal sinuses are uncommonly reported in the literature. However, over the last several years, we have encountered an increasing number of cases of metastatic neuroblastoma to the central nervous system and head and neck. This article will review the common and uncommon imaging manifestations of metastatic neuroblastoma, with emphasis on the orbits, maxillofacial bones, and paranasal sinuses.


Assuntos
Ossos Faciais/diagnóstico por imagem , Neuroblastoma/diagnóstico por imagem , Neuroblastoma/secundário , Neoplasias Cranianas/diagnóstico por imagem , Neoplasias Cranianas/secundário , Tomografia Computadorizada por Raios X/métodos , Adolescente , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Recém-Nascido , Masculino
5.
AJR Am J Roentgenol ; 194(5): 1223-9, 2010 May.
Artigo em Inglês | MEDLINE | ID: mdl-20410407

RESUMO

OBJECTIVE: Although neuroblastoma is a common childhood malignancy, which frequently metastasizes, involvement of the CNS is rarely reported in the literature. However, over the past several years, we have encountered an increasing number of cases of metastatic neuroblastoma to the CNS. This metastatic potential and changing metastatic pattern may, in part, be due to advances in medical treatment, leading to prolonged survival. This article will review the common and uncommon manifestations of metastatic neuroblastoma with an emphasis on the skull, dura, brain, ventricles, and leptomeninges. CONCLUSION: Neuroblastoma has diverse manifestations including masquerading as primary neurologic disease. This disease must be considered in a child with any unexplained neurologic disorder. Realizing that neuroblastoma may represent the cause of neurologic disease in a child will lead to earlier diagnosis.


Assuntos
Neoplasias Encefálicas/diagnóstico , Neoplasias Encefálicas/secundário , Imageamento por Ressonância Magnética/métodos , Neuroblastoma/diagnóstico , Neuroblastoma/secundário , Tomografia Computadorizada por Raios X/métodos , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Masculino
6.
AJR Am J Roentgenol ; 191(2): 589-97, 2008 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-18647937

RESUMO

OBJECTIVE: The purpose of this study was to review the craniofacial and intracranial clinical and radiologic manifestations of patients diagnosed with Langerhans cell histiocytosis (LCH). This report will compare the frequency of the various manifestations found in our series with those reported in the medical literature. CONCLUSION: In LCH, involvement of the calvaria, skull base, maxillofacial bones, and hypothalamic-pituitary axis is fairly common. The precise location of these lesions contributes to the variety of clinical manifestations of LCH, which includes scalp and/or facial swelling, seizures, hearing loss, recurrent otitis media, gingival bleeding, proptosis, diabetes insipidus, and cranial nerve palsies.


Assuntos
Doenças Ósseas/patologia , Encefalopatias/patologia , Histiocitose de Células de Langerhans/patologia , Adolescente , Adulto , Criança , Pré-Escolar , Edema/patologia , Feminino , Humanos , Lactente , Imageamento por Ressonância Magnética , Masculino , Estudos Retrospectivos , Crânio/patologia , Tomografia Computadorizada por Raios X
7.
AJR Am J Roentgenol ; 188(6): W506-11, 2007 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-17515339

RESUMO

OBJECTIVE: Our objective was to describe the CT features of spontaneous isolated celiac artery dissection in a series of six otherwise healthy patients with acute abdominal pain. CONCLUSION: Although once believed rare, isolated spontaneous celiac artery dissection should be considered in the diagnosis of acute abdominal pain, especially in middle-aged adults.


Assuntos
Angiografia/métodos , Dissecção Aórtica/diagnóstico por imagem , Artéria Celíaca/diagnóstico por imagem , Tomografia Computadorizada por Raios X/métodos , Idoso , Idoso de 80 Anos ou mais , Dissecção Aórtica/cirurgia , Artéria Celíaca/cirurgia , Humanos , Masculino , Pessoa de Meia-Idade , Resultado do Tratamento
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