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Int J Med Mushrooms ; 21(11): 1051-1063, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-32450015

RESUMO

This work investigated the antiradical, antibacterial, and antifungal properties of a methanol extract from Fuscoporia torulosa (PeruMyc1834) fruit body from Central Italy. The ITS partial sequence of the F. torulosa strain matched at a 100% rate those of various strains belonging to the species. Two complementary test systems, namely α,α-diphenyl-ß-picrylhydrazyl (DPPH) radical scavenging and ß-carotene/linoleic acid systems, were used. Free radical scavenging, measured by DPPH assay on methanol extract, showed an activity of 38.17 ± 2.74% of Trolox activity. The methanol extract of F. torulosa inhibited the growth of Gram-positive bacteria, particularly those belonging to the genus Bacillus (i.e., B. subtilis and B. cereus), better than Gram-negative bacteria. All the fungal isolates used in the present study for antifungal activity inhibited their growth when a concentration of 2.27 mg mL-1 of methanol extract was used (minimum inhibitory concentration from < 0.28 to 2.27 mg mL-1). This study established that the extracted antioxidant and antimicrobial compounds produced by F. torulosa can be exploited in treating diseases that affect humans, plants, and animals. There is a need to carry out further study to establish the chemical composition of the methanol extract.


Assuntos
Antibacterianos/farmacologia , Antifúngicos/farmacologia , Basidiomycota/química , Misturas Complexas/farmacologia , Sequestradores de Radicais Livres/farmacologia , Animais , Antibacterianos/isolamento & purificação , Antifúngicos/isolamento & purificação , Basidiomycota/classificação , Basidiomycota/genética , Basidiomycota/isolamento & purificação , Compostos de Bifenilo/metabolismo , Misturas Complexas/isolamento & purificação , Sequestradores de Radicais Livres/isolamento & purificação , Carpóforos/química , Bactérias Gram-Negativas/efeitos dos fármacos , Bactérias Gram-Positivas/efeitos dos fármacos , Itália , Testes de Sensibilidade Microbiana , Picratos/metabolismo
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