RESUMO
We report a case of gastric signet cell carcinoma, presenting as cardiac tamponade, in a young male patient. The diagnosis of gastric signet cell carcinoma was confirmed by immunohistochemistry of the lymph node specimen in our patient.
Assuntos
Carcinoma de Células em Anel de Sinete/patologia , Tamponamento Cardíaco/etiologia , Derrame Pericárdico/etiologia , Neoplasias Gástricas/patologia , Adulto , Humanos , Metástase Linfática , Masculino , Derrame Pericárdico/complicaçõesRESUMO
The constellation of pseudoxanthoma elasticum, ocular involvement and vascular disturbances is termed Gronblad Strandberg syndrome. Pseudoxanthoma elasticum is a genetic disorder characterized by progressive calcification and fragmentation of elastic fibres in the skin, retina and the cardiovascular system. Typically the cutaneous lesions begin in childhood, but because of their asymptomatic nature they are not noted until adolescence. In some individuals, skin lesions do not develop until later in life. If recognized early, the occurrence of retinal and gastrointestinal hemorrhage and cardiovascular complications can be minimized.
Assuntos
Artéria Basilar/diagnóstico por imagem , Pseudoxantoma Elástico/diagnóstico , Insuficiência Vertebrobasilar/diagnóstico , Idoso , Biópsia , Tecido Elástico/patologia , Humanos , Angiografia por Ressonância Magnética , Masculino , Pseudoxantoma Elástico/complicações , Pseudoxantoma Elástico/genética , Radiografia , Pele/patologia , Insuficiência Vertebrobasilar/complicaçõesRESUMO
Pyrexia of unknown origin has always been a challenging problem to diagnose for physicians. Here we present a case of a splenic tumor, which after histopathology and immunohistochemistry, two possibilities were considered, a diffuse large cell lymphoma--plasmablastic variant and second an anaplastic plasmacytoma. The patient was treated with chemotherapy and on followup he has no evidence of recurrence or any residual lesion.
Assuntos
Febre de Causa Desconhecida/diagnóstico , Linfoma Difuso de Grandes Células B/diagnóstico , Plasmocitoma/diagnóstico , Neoplasias Esplênicas/diagnóstico , Febre de Causa Desconhecida/fisiopatologia , Humanos , Linfoma Difuso de Grandes Células B/fisiopatologia , Masculino , Pessoa de Meia-Idade , Plasmocitoma/fisiopatologia , Neoplasias Esplênicas/fisiopatologia , Neoplasias Esplênicas/cirurgiaRESUMO
Macrophage Activation Syndrome is a rare and potentially fatal disease, to be considered in patients with a SIRS like clinical presentation. Falling ESR and hyperferritinemia in the appropriate clinical setting can be the greatest clues. We report a case in which a female admitted with fever and rash, initially had systemic inflammatory response syndrome (SIRS) like clinical presentation, but eventually proved to be a rare case of fatal Macrophage Activation Syndrome.