Educational video to improve memorization of preoperative information in parotidectomy: A randomized controlled study.

AIM: To compare the number of risks memorized by patients before parotid surgery for benign tumor after receiving standard oral and written information versus the same information with an additional educational video, in France. MATERIAL AND METHODS: A single-center prospective controlled randomized study was conducted from July 2017 to October 2019 with 69 patients operated on for a-priori benign parotid tumor. Median age was 52 years (range, 20 to 87 years). Mean interval from preoperative consultation to surgery was 100 days. The cohort was randomized between two groups: without (control group) and with (experimental group) additional audiovisual information. The main endpoint was the number of risks remembered, out of seven listed. Results were expressed as median with interquartile range. The secondary endpoint was the impact on memorization of age, gender, education level, interval to surgery, and type of planned surgery. RESULTS: Twenty-nine patients were analyzed in the control group and 27 in the experimental group. The number of risks remembered ranged from zero to five and was significantly greater in the experimental group: median 2 [IQR, 2-3] versus 1 [0-2] (P<0.005). The best remembered was transient facial palsy (41 patients). In the control group, one third of the patients did not remember any risks. There were no significant correlations between individual factors and memorization. CONCLUSION: Although subject to many methodological biases, our study showed that additional audiovisual information improved memorization of the risks associated with parotidectomy.

First-line treatment of exudative vocal fold-lesions by in-office local corticosteroid injection: A literature review.

OBJECTIVES: There are emerging reports of the effectiveness of in-office awake vocal-fold corticosteroid injection in the treatment of exudative vocal-fold lesions. The aim of this study was to review this therapy and specify indications, practical modalities and outcomes. STUDY DESIGN: Systematic review of the literature without meta-analysis. METHODS: A systematic review by PubMed search for the period January 2000 to December 2018 was carried out. RESULTS: Nine articles were included, for a total of 502 lesions: nodules (46.4%), polyps (31.7%), and Reinke's edema (21.9%). Submucosal injection of low-dose triamcinolone acetonide (0.1 to 0.3mL) was transoral, transcutaneous or transnasal via flexible endoscope with operating channel. Lesion volume was significantly reduced in more than 90% of cases, with significant vocal improvement in all studies. Relapse rates ranged between 4% and 31%, with time to relapse of 1 to 40 months. CONCLUSIONS: First-line treatment of exudative glottic lesions by submucosal corticosteroid injection provides at least transient significant reduction in lesion volume and vocal improvement. It is consensually reserved to moderate-sized mainly exudative lesions without fibrosis. In-office injection provides an immediate therapeutic response in case of vocal impairment, enabling surgery under general anesthesia to be postponed.

[Singular, systemic, self-reactive IgG patterns related to age: relationship with cerebral malaria susceptibility in exposed subjects residing in an endemic area in Abidjan, Côte-d'Ivoire]. / Singularité des profils d'autoréactivité systémique en fonction de l'âge: relations avec la susceptibilité au neuropaludisme chez les sujets exposés en région endémique à Abidjan, Côte-d'Ivoire.

The impact of autoimmunity on malaria-infection evolution reported by various works has led us to compare reactive patterns of self-dependent systemic IgG from 54 patients aged less than 15 years old to those from 46 subjects older than 15 years. These subjects were divided into 34 Plasmodium falciparum asymptomatic carriers (ACs), 30 cases of uncomplicated malaria (UM), and 36 patients suffering from cerebral malaria (CM) living in the same endemic area. The reactivity of the plasma antibodies against human brain tissue extract was assessed by western blotting. Comparative analysis of reactive bands (linear discriminant analysis, LDA) revealed the existence of patterns that distinguish, among the more susceptible subjects aged less than 15 years old, the different clinical forms. In contrast, in less susceptible subjects aged more than 15 years old, the patterns are homogenous and do not allow the separation of these clinical forms. This self-reactive repertoire might be witnessed as an imprint of the clinical tolerance acquired during the years of living in endemic areas. The singularity of this profile under the age of 15 years might have a prognostic value.