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Cell Mol Biol Lett ; 28(1): 37, 2023 May 09.
Artigo em Inglês | MEDLINE | ID: mdl-37161350

RESUMO

Metabolic reprogramming is a well-known feature of cancer that allows malignant cells to alter metabolic reactions and nutrient uptake, thereby promoting tumor growth and spread. It has been discovered that noncoding RNAs (ncRNAs), including microRNA (miRNA), long noncoding RNA (lncRNA), and circular RNA (circRNA), have a role in a variety of biological functions, control physiologic and developmental processes, and even influence disease. They have been recognized in numerous cancer types as tumor suppressors and oncogenic agents. The role of ncRNAs in the metabolic reprogramming of cancer cells has recently been noticed. We examine this subject, with an emphasis on the metabolism of glucose, lipids, and amino acids, and highlight the therapeutic use of targeting ncRNAs in cancer treatment.


Assuntos
MicroRNAs , Neoplasias , RNA Longo não Codificante , RNA não Traduzido/genética , RNA Longo não Codificante/genética , Transporte Biológico , MicroRNAs/genética , Glucose , RNA Circular , Neoplasias/genética
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