RESUMO
OBJECTIVE: To demonstrate the efficacy of a digital nerve block for improving pulse oximetry in conditions of low tissue perfusion. METHOD: A randomized single-blind study of adult patients undergoing surgery under general anesthesia for conditions characterized by hypoperfusion. Patients were assigned to a control group or an experimental group. The experimental group received a digital nerve block in the middle finger of the left hand; a sensor was then placed on the finger for between 120 and 300 minutes. Age, sex, diagnosis, total observation time (TOT), percentage of time with no pulse oximeter signal (NoPO), and percentage of time with an unstable pulse oximeter signal (UnstPO) were recorded. Each patient was questioned between 16 and 24 hours after surgery and was examined for flushing, paresthesia, hypoesthesia, pain, and ecchymosis. The chi2 test was used to compare dichotomized or nominal variables and the t test was used to compare age, TOT, NoPO, and UnstPO. Values of P<.05 were considered statistically significant in both cases. RESULTS: Fifty patients were randomized to each group. A total of 82 patients remained in the study (control group=42, experimental group=40). There were no significant between-group differences in diagnoses or TOT. The mean values for NoPO and UnstPO were higher in the control group than in the experimental group (11.1% vs 4.4% and 35.9% vs 15.7%, respectively; P<.001). CONCLUSION: A digital nerve block can be used to prevent pulse oximetry failures in conditions of low peripheral perfusion.
Assuntos
Bloqueio Nervoso Autônomo , Dedos/irrigação sanguínea , Isquemia/sangue , Oximetria/métodos , Oxigênio/sangue , Adulto , Idoso , Falha de Equipamento , Feminino , Dedos/inervação , Hemorragia/sangue , Humanos , Masculino , Pessoa de Meia-Idade , Peritonite/sangue , Choque/sangue , Método Simples-Cego , VasoconstriçãoRESUMO
The case of a 15-years-old female patient is presented, who referred pain and presence of a mass in the left upper quadrant of the abdomen. Diagnostic imaging showed a 9 cm diameter cystic lesion in the tail of the pancreas which was removed surgically. Histology demonstrated a pancreatic mucinous cystadenoma with borderline biological behaviour. A review of the literature related to cystic neoplasms of the pancreas is realized.
Assuntos
Cistadenoma Mucinoso/patologia , Neoplasias Pancreáticas/patologia , Adolescente , Cistadenoma Mucinoso/cirurgia , Feminino , Humanos , Pâncreas/patologia , Pancreatectomia , Neoplasias Pancreáticas/cirurgiaRESUMO
Son muchas variables que intervienen en la fabricación de tabletas e influyen decisivamente en el medicamento que va a ser elaborado; entre ellas tiene marcada incidencia, la humedad residual. En este trabajo se comparan dos principios activos: ácido glutámico y tolbutamida, que se encuentran en alta e igual dosificación en las tabletas en comparación con granulado base de lactosa; se realizan las preparaciones habituales mediante el método de vía húmeda convencional, se deseca en horno eléctrico y se toman muestras de ellos progresivamente. Se realizan los ensayos físicos correspondientes; humedad residual, ángulo de reposo, velocidad de flujo, granulometrías y a su vez elaborando tabletas de éstos a las diferentes humedades residuales, se les realiza determinaciones física de: peso, dureza, altura y desintregación(AU)
Assuntos
Umidade , Comprimidos , Indústria FarmacêuticaRESUMO
Se presenta el resultado de las actividades realizadas durante dos años de ejecución del Programa de Control de la Tuberculosis integrado a los Servicios Generales de salud, también denominado programa horizontal, y que segùn el criterio del Comité de Expertos de la OMS es el más aconsejable. Se verifica, en la Provincial Oriente-Norte, el rendimiento elevado que se obtiene en el diagnóstico, tratamiento y curación de los nuevos casos de tuberculosis pulmonar y en el examen y protección de sus contactos. Se plantea que la extensión del programa a toda la nación y su enrequecimiento por el aporte de la experiencia nacional en internacional nos llevará al muy cercano control de la tuberculosis y más adelante a su erradicación(AU)