1.
Rev Med Interne
; 30(10): 900-3, 2009 Oct.
Artigo
em Francês
| MEDLINE
| ID: mdl-19457597
RESUMO
The standard regimen for the treatment of chronic hepatitis C virus (HCV) is peginterferon alpha-2a or -2b associated with ribavirine. The recommended duration of treatment for genotype 2 HCV infection is 24 weeks. However, the relatively poor drug tolerance often leads to a reduction or a discontinuation of the treatment. Here, we report two female patients who discontinued antiviral therapy after less than 6 weeks for intolerance and who experienced a sustained virological response. A treatment of 3 to 5 weeks may be enough for genotype 2 HCV eradication. However, there is not sufficient evidence in 2009 to recommend a reduced treatment duration.
Assuntos
Hepatite C Crônica/tratamento farmacológico , Antivirais/uso terapêutico , DNA Viral/análise , Feminino , Hepatite C Crônica/genética , Humanos , Interferon alfa-2 , Interferon-alfa/uso terapêutico , Adesão à Medicação , Pessoa de Meia-Idade , Polietilenoglicóis/uso terapêutico , Proteínas Recombinantes , Ribavirina/uso terapêutico
2.
Hepatology
; 23(4): 938-40, 1996 Apr.
Artigo
em Inglês
| MEDLINE
| ID: mdl-8666354