Effects of Ending the Use of Seclusion and Mechanical Restraint in the Pennsylvania State Hospital System, 2011-2020.

The Pennsylvania State Hospital System's use of containment procedures has been studied for >30 years. This prospective study assessed the effects of ending the use of seclusion and mechanical restraint in the system's six civil hospitals and two forensic centers from 2011 to 2020. The study examined the effect of this change on key safety measures: physical restraint, assaults, aggression, and self-injurious behavior. In total, 68,153 incidents, including 9,518 episodes of physical restraint involving 1,811 individuals, were entered into a database along with patients' demographic and diagnostic information. All data were calculated per 1,000 days to control for census changes. During the study, mechanical restraint was used 128 times and seclusion four times. Physical restraint use decreased from a high of 2.62 uses per 1,000 days in 2013 to 2.02 in 2020. The average length of time a person was held in physical restraint was reduced by 64%, from 6.6 minutes in 2011 to 2.4 minutes in 2020 (p<0.001). All safety measures improved or were unchanged. Use of unscheduled medication did not change. The hospital system safely ended the use of mechanical restraint and seclusion by using a recovery approach and by following the six core strategies for seclusion and restraint reduction.

The Effects of Botulinum Toxin A on Pain in Ischemic Vasospasm.

PURPOSE: The purpose was to describe the impact of botulinum toxin A (BTX-A) administration in patients with ischemic vasospasm on the magnitude and timing of pain relief and subsequent effect on opioid use. The secondary purposes were to determine the role of photoplethysomgraph (PPG) testing on treatment decisions, effect on patient-reported outcomes, and additional procedures. METHODS: A retrospective analysis of patients who received BTX-A injections was performed. Botulinum toxin type A was injected subcutaneously in symptom-specific 2-level patterns. Pain, shortened version of the Disabilities of the Arm, Shoulder, and Hand (QuickDASH), and opioid use (quantified by median morphine equivalents) were recorded and the need for repeat injections or unplanned surgeries was assessed. RESULTS: All patients (n = 20 patients; 31 hands) had ischemic pain from vasospasm and failed multiple pharmacological options. Average follow-up was 10.5 months. All patients had abnormal PPG amplitude (mean, 6.43 mm) at room temperature and increased amplitude (mean, 19.55 mm) after immersion in warm water. All patients (n = 12) with a PPG amplitude increase of 4 mm or greater had clinical success. Eleven of 13 patients had a clinically relevant decrease in pain at 20 minutes after injection. Clinically significant pain relief was sustained for 3 months (visual analog scale decreased by a mean of 4). Median morphine equivalent usage view decreased from 82.5 to 0 after injection. Patient-reported disability (QuickDASH) improved from 49 before treatment to 29 and 26 at 6 weeks and 6 months after BTX-A injection, respectively. Three patients were retreated for recurrent symptoms. Four patients required unplanned secondary procedures. CONCLUSIONS: Botulinum toxin type A administration can result in rapid (within 20 minutes) and sustained pain relief for several months with a reduction in opioid prescriptions. Botulinum toxin type A administration also improved patient-reported disability for 6 months. Use of PPG testing to determine baseline perfusion deficit and capacity to improve after warm water immersion was helpful in consideration of BTX-A use. TYPE OF STUDY/LEVEL OF EVIDENCE: Therapeutic IV.

Comparison study of a multispectral zoom lens using standard and novel optical materials.

We demonstrate two broadband multispectral infrared (3.5-11.5 µm), zoom (3×) systems with focal lengths adjustable from 50 mm to 150 mm. Both systems are successful in meeting the modulation transfer function (MTF) requirement of 20 lp/mm. The difference between the two designs is that one employs novel infrared-transparent glasses that permit the designer to achieve an improved system performance with dramatically fewer lens elements. The impact of these materials on the design performance is discussed in terms of MTF and chromatic focal shift as a function of temperature, and we conclude with a brief description of these new glasses and their optical functionality.

Risk factors for failed closed reduction of pediatric supracondylar humerus fractures.

The purpose of this retrospective study was to examine pediatric supracondylar humerus fractures at a Level I trauma center. Data were analyzed to identify risk factors associated with closed reduction failure. Closed pediatric supracondylar humerus fractures that were treated at the authors' trauma center between October 1997 and January 2009 were reviewed. The main outcome variable was necessity of open reduction. To determine which factors were independently associated with a failed closed reduction, a multivariate logistic model was fit predicting open reduction status.A total of 174 patients required operative treatment. Of these, 23 underwent open reduction and 151 underwent with closed reduction and percutaneous pinning. For patients who required open reduction, 39.1% had an associated injury compared with 14.6% of patients treated with closed reduction (P=.008). Average time from presentation to surgery was 4.1 hours in the open reduction and 6.3 hours in the closed reduction group (P=.049). Risk factors that significantly predicted failure of closed reduction were the presence of an associated injury, initial fracture displacement, and Gartland type III fracture (P=.008, .03, and .023, respectively).Associated injury, large initial fracture displacement, and Gartland type III factures were statistically significant independent risk factors for closed reduction failure. Increased time from injury to presentation demonstrated a trend toward open reduction. Consideration should be given to the expedient transfer of patients with type III supracondylar humerus fractures with associated injuries when definitive care will be provided at another institution.

Predicting the outcome of revision carpal tunnel release.

PURPOSE: To test the hypothesis that the result of steroid injection in the carpal tunnel in a patient with recurrent carpal tunnel symptoms would serve as a good predictor of the outcome of later carpal tunnel release (CTR). METHODS: We conducted a retrospective review of all patients who underwent revision CTR for recurrent or persistent carpal tunnel syndrome over a 2-year period at our institution. A total of 28 wrists in 23 patients met inclusion criteria. We evaluated patients to determine whether preoperative factors or the result of injection predicted the outcome of revision CTR. We used a multivariate logistic regression analysis to predict surgical success when multiple preoperative findings were considered. RESULTS: Of the 23 wrists that had relief from injection, 20 had symptom improvement with surgery. Although they did not reach statistical significance, the sensitivity and positive predictive value for injection alone predicted outcome of revision CTR in 87%. No patient characteristic or physical examination finding predicted successful revision CTR. Multivariate logistic regression analysis combining preoperative injection results with physical examination findings (numbness and/or motor weakness in median nerve distribution, positive Durkin test, and positive Phalen test) provided a sensitivity of 100% and a specificity of 80%. CONCLUSIONS: In a small group of patients with recurrent carpal tunnel syndrome, cortisone injection into the carpal tunnel was not, by itself, a statistically significant predictor of successful revision surgery. However, relief from injection as a diagnostic test for predicting successful revision CTR was found to have both a high sensitivity and a positive predictive value. Coupled with the components of the physical examination, injection provides a good screening test to establish surgical success with revision CTR. TYPE OF STUDY/LEVEL OF EVIDENCE: Therapeutic III.

Results of endoscopic carpal tunnel release relative to surgeon experience with the Agee technique.

PURPOSE: To establish the rate of iatrogenic injury after endoscopic carpal tunnel release (ECTR) for a surgeon in the first 2 years of practice; to report the rate of conversion from ECTR to open carpal tunnel release (OCTR), the reason for conversion, and any increase in morbidity found in patients converted to OCTR; and to determine whether the conversion rate decreased with increasing surgeon experience. METHODS: We conducted a retrospective review of patients undergoing ECTR by a single surgeon in the first 2 years of practice. Data collected or calculated included symptom relief, rate of conversion to OCTR, reason for conversion, and neurovascular complications. For patients converted to OCTR, we assessed satisfaction and function using the Disabilities of the Arm, Shoulder, and Hand questionnaire. We compared these results for 1 to 6 months, 7 to 12 months, and 12 to 24 months to determine whether a learning curve was present. RESULTS: A total of 278 patients (358 procedures) underwent ECTR. Of these, 12 patients required conversion to OCTR during the index procedure over a 2-year period. In the first 6 months of practice, 8 of 71 ECTRs were converted to OCTR compared to 1 of 72 in the second 6 months. This was a statistically significant decrease (p = .017). In year 2, 3 of 215 patients were converted to OCTR. Average Disabilities of the Arm, Shoulder, and Hand score for patients converted from ECTR to OCTR was 9. No patients required repeat surgery for recurrence of carpal tunnel symptoms. We observed no major neurovascular complications. CONCLUSIONS: A learning curve for ECTR was present. Rates of conversion significantly diminished with increased surgeon and anesthesia experience. Patients requiring conversion showed no variation in Disabilities of the Arm, Shoulder, and Hand scores from established values after OCTR. Patients may be at a higher risk of conversion to OCTR during the learning curve time period; nevertheless, we found no increased morbidity. TYPE OF STUDY/LEVEL OF EVIDENCE: Prognostic III.

Incidence of scapholunate ligament dissociation in patients with aspiration-confirmed gout.

PURPOSE: To determine the incidence of scapholunate (SL) dissociation in patients with aspiration-confirmed gout of the wrist and aspiration-confirmed gout in any joint excluding the wrist. METHODS: Geisinger Medical Center uses the EPIC electronic medical record system, which maintains International Classification of Diseases, 9th Revision, Clinical Modification and Current Procedural Terminology coding information for every patient encounter in our hospital system. We queried this electronic medical record system from 1998 to 2008 using the International Classification of Diseases, 9th Revision, Clinical Modification codes for gout as well as Current Procedural Terminology codes for aspiration of a minor, intermediate, or major joint. We then evaluated medical records of patients meeting criteria for the presence of wrist x-rays. We examined x-rays for SL interval, SL angle, and capitolunate angle and determined the incidence of SL dissociation in all patients with a diagnosis of gout confirmed by joint aspiration. RESULTS: We reviewed a total of 1,105 cases; 159 patients met inclusion criteria. Of 159 patients, 20 had aspiration-confirmed gout in the wrist. We determined incidence using 2 definitions: (1) one or more positive radiographic criteria for SL dissociation, and (2) two or more positive radiographic criteria. The incidence of SL dissociation in wrists with aspiration-confirmed gout was 60% by definition 1 and 25% by definition 2. The average SL interval was 2.95 mm. The remaining 139 patients had aspiration-confirmed gout in joints other than the wrist. A total of 69 patients had 1 or more positive criteria for SL dissociation, whereas 18 had 2 or more positive criteria, making the incidence of SL dissociation 49.6% and 12.9%, respectively. The average scapholunate interval was 2.28 mm. The incidence of SL dissociation in patients with aspiration-confirmed gout in any joint was 50.9% and 14.5%, based on the above definitions. CONCLUSIONS: This study establishes the incidence of SL dissociation in patients with gouty arthropathy of the wrist as 60% and 25%, respectively, based on the above definitions. In addition, our study suggests that, as a result of the systemic nature of gout, a patient with aspiration-confirmed gout at a joint remote from the wrist might have subclinical effects in the wrist, leading to SL dissociation over time. TYPE OF STUDY/LEVEL OF EVIDENCE: Prognostic IV.

Psychiatric use of unscheduled medications in the Pennsylvania state hospital system: effects of discontinuing the use of P.R.N. orders.

The objective of this prospective study was to assess patient exposure to the psychiatric use of unscheduled medications at all nine Pennsylvania state hospitals and to unify practice guidelines in this regard. In August 2004, a decision was made to discontinue the use of p.r.n. orders for psychiatric indications. All unscheduled medications, (p.r.n. and STAT physician's order) administered for psychiatric indications were entered into a uniform database. A total of 46,913 unscheduled medications were administered to people served in the hospital system throughout this 15 month study. During March 2004, 87.7 unscheduled medications per 1,000 days-of-care were administered in the hospital system. During the last month of this study, May 2005, this rate had decreased to 17 per 1,000 days-of-care. Many hospital safety measures significantly improved as a result of this change. Cessation of p.r.n. medication use for psychiatric indications has significantly decreased patient exposure to unnecessary psychotropic medications and has resulted in a safer hospital system.