[Predictive factors of 2009 H1N1 virus infection in patients with influenza syndrome]. / Factores predictivos de infección por el virus de la gripe H1N1 2009 en pacientes con síndrome gripal.

INTRODUCTION: Polymerase chain reaction (PCR) testing is one of the better techniques for viral detection in nasopharyngeal swabs. The objective of this study was to assess the percentage of positive swabs and to determine whether there were differences according to PCR positivity. MATERIAL AND METHODS: A retrospective study of 362 patients with flu syndrome attended at the Emergency Department between July 15 and December 15, 2009, in whom PCR of nasopharyngeal swabs for the detection of H1N1 2009 influenza virus was performed. Those cases in which swab testing was adequately requested were identified, and patients were divided into two groups according to positive or negative results for H1N1 2009 influenza virus. RESULTS: Nasopharyngeal swab was inadequately ordered in 87. In the remaining 275 patients, PCR was positive in 141. Patients with positive nasopharyngeal swabs were younger (mean [SD] age 36.1 [15] vs 42.3 [18] years, P= 0.002), had lower white blood cell, neutrophil and lymphocyte counts, lower serum concentrations of C-reactive protein (5.15 [5] vs 10.5[12] mg/dL, P= 0.036) and lower incidence of radiological infiltrates (20.5% vs 33%, P= 0.036). In the logistic regression analysis, age, serum C-reactive protein levels, and lymphocyte count were independently associated with a positive nasopharyngeal swab. CONCLUSIONS: About 50% of patients with flu syndrome had positive nasopharyngeal swabs for H1N1 2009 influenza virus. Age, C-reactive protein, and lymphocyte count were independent predictors of positivity.

Tuberculosis en población inmigrante: casos diagnosticados en urgencias según el lugar de procedencia / Tuberculosis in an immigrant population: emergency department diagnoses, analyzed by place of origin

Objetivo: El Hospital del Mar de Barcelona cubre un área de influencia (AI) de 350.000habitantes. En 2006, el 15,7% de esta población eran inmigrantes. El objetivo de este estudio es describir la distribución por países y zonas geográficas de los pacientes diagnosticados de tuberculosis en urgencias. Adicionalmente, se muestra el país y zona geográfica de procedencia de los inmigrantes censados en nuestra AI. Método: Se incluyeron los inmigrantes diagnosticados de tuberculosis durante 2006 y2007. Los datos poblacionales se obtuvieron del padrón municipal. Para cada país y zona geográfica se evaluó el porcentaje que representaba respecto a la población inmigrante censada (PIC), y el porcentaje respecto al total de tuberculosis en inmigrantes diagnosticados en urgencias (PTU). Se calculó el índice PTU/PIC para evaluar los casos de tuberculosis ajustados según los datos poblacionales. Resultados: El número de inmigrantes censados en 2006 fue de 54.057. Las nacionalidades más frecuentes fueron la pakistaní (14,1%) y la ecuatoriana (10,1%) y las zonas geográficas fueron Latinoamérica (38,3%) y Europa Occidental (19,2%). Se diagnosticaron60 casos de tuberculosis en inmigrantes, y fueron más frecuentes los casos procedentes de Pakistán (26,7%), seguidos de Bolivia (15%), Europa del Este (11,7%) y África del Norte (8,3%). Las mayores puntuaciones PTU/PIC correspondieron a Bolivia, Pakistán, Europa del Este y Asia Central. Conclusiones: La mayoría de los nuevos casos de tuberculosis en inmigrantes visitados en urgencias corresponden a pacientes originarios de Pakistán y de Latinoamérica, pero el mayor índice PTU/PIC se observa en los procedentes de Bolivia y Europa del Este (AU)

Objectives: Hospital de Mar in Barcelona serves a population of 350 000 inhabitants. In 2006, 15.7% of this population consisted of immigrants to Spain. The aim of this study was to describe the distribution by country and geographic region of immigrant patients diagnosed with tuberculosis in the emergency department. Additionally, we show the countries and geographic regions of origin of all immigrants identified by the census as residing in the area the hospital serves. Methods: The study included immigrants diagnosed with tuberculosis in 2006 and 2007. Population data were obtained from municipal census records. By country and region of origin, we analyzed the number of immigrants with tuberculosis, calculating percentages of the overall immigrant population recorded in the census (PIPC) and of the total number of immigrants diagnosed with this disease in the emergency department (PTED). The ratio between the two percentages (PTED/PIPC) was calculated to create an index reflecting the number of tuberculosis cases adjusted for population data. Results: A total of 54 057 immigrants were identified in the 2006 census. The largest national groups were those from Pakistan (14.1%) and Ecuador (10.1%). The largest regional groups were those from Latin America (38.3%) and Western Europe (19.2%). Sixty cases of tuberculosis were diagnosed in immigrants. Most of these patients came from Pakistan(26.7%) and Bolivia (15%). Attending to geographic region, patients from Eastern Europe (11.7%) and those from North Africa (8.3%) were the most frequently diagnosed. The highest PTED/PIPC indexes corresponded to Bolivia, Pakistan, Eastern Europe, and Central Asia. Conclusions: Most new cases of tuberculosis in immigrants diagnosed in the emergency department were found in patients from Pakistan and Latin America, but the highest PTED/PIPC indices were those for Bolivia and Eastern Europe (AU)