RESUMO
The content of IgE was measured over time in 14 children with periarteritis nodosa. No significant relation was established between allergic reactions in the anamnesis and IgE elevation in periarteritis nodosa. A relationship was discovered between the rise of IgE content and disease activity, the intensity of the clinical manifestations, vascular ones in particular. During a remission of periarteritis nodosa, the content of IgE remained within normal in all the children.
Assuntos
Imunoglobulina E/análise , Poliarterite Nodosa/imunologia , Adolescente , Fatores Etários , Criança , Pré-Escolar , Feminino , Humanos , MasculinoRESUMO
Altogether 173 children with systemic scleroderma (SSD) were examined. Of these, 45 were with eosinophilia. It was discovered that associated SSD and eosinophilia ran a course marked by more well-defined exudative reactions, with the heart being injured more frequently and gravely. A correlation was noted between the "sclerodermic" heart and the eosinophil count in the peripheral blood. The relationship between eosinophilia and the content of the total serum IgE in SSD is discussed as is the role of age-associated and constitutional factors in the development of eosinophilia in SSD children.
Assuntos
Eosinofilia/complicações , Cardiopatias/etiologia , Escleroderma Sistêmico/complicações , Fatores Etários , Criança , Eosinofilia/etiologia , Humanos , Imunoglobulina E/análise , Escleroderma Sistêmico/imunologiaRESUMO
Altogether 125 children with connective tissue dysplasia and mitral valve prolapse were subjected to clinical and echographic examinations. Dilation of the aortic root, elevation of pulmonary artery pressure and derangement of myocardial contractility were discovered. These disorders occurred as a result of disseminated connective tissue abnormalities. It is noted that children with connective tissue dysplasia and mitral valve prolapse require prophylactic medical examination because of progressive alterations on the part of the cardiovascular system with age.
Assuntos
Arritmias Cardíacas/diagnóstico , Síndrome de Ehlers-Danlos/fisiopatologia , Sistema de Condução Cardíaco/fisiopatologia , Síndrome de Marfan/fisiopatologia , Prolapso da Valva Mitral/fisiopatologia , Adolescente , Arritmias Cardíacas/etiologia , Criança , Pré-Escolar , Ecocardiografia , Síndrome de Ehlers-Danlos/complicações , Humanos , Síndrome de Marfan/complicações , Prolapso da Valva Mitral/complicaçõesRESUMO
Twenty children with systemic lupus erythematosus (SLE) and 13 children with systemic scleroderma were examined by electrocardiography, tetrapolar chest rheography, rheopulmonography and echocardiography. Half of the cases manifested pulmonary hypertension, which was more appreciable in SLE patients. The results of rheopulmonographic and echocardiographic research methods turned out highly comparable.
Assuntos
Lúpus Eritematoso Sistêmico/complicações , Doença Cardiopulmonar/diagnóstico , Escleroderma Sistêmico/complicações , Adolescente , Pressão Sanguínea , Criança , Ecocardiografia , Eletrocardiografia , Feminino , Humanos , Hipertensão Pulmonar/diagnóstico , Masculino , Pletismografia de Impedância , Artéria Pulmonar/fisiologia , Doença Cardiopulmonar/fisiopatologiaRESUMO
Neurologic manifestations were examined in 25 patients with the Ehlers-Danlos syndrome. Injuries to vessels of the brain and spine, arteriovenous malformation, muscular and vertebrogenic lesions, headaches, and vegetative disorders were diagnosed. The clinical and laboratory data are provided whatever the presence or lack of neurologic symptomatology. The problem of the pathogenesis and treatment of neurologic manifestations associated with the Ehlers-Danlos syndrome are discussed.