RESUMO
Melanocytic nevi result from the proliferation of melanocytes at the dermal-epidermal junction and/or in the dermis and very rarely affect the nail matrix and bed. Intradermal nevi are tumors often diagnosed in routine clinical dermatological practice, with typical clinical and histopathologic aspects, and found in a wide variety of skin sites. We report a case of intradermal melanocytic nevus of the proximal nail fold with uncommon intraoperative gross findings and without involvement of the nail bed or matrix, showing intradermal component only, which draws our attention to the possible different presentation of melanocytic lesions. No description of intradermal nevi at this site has been reported in the literature so far.
RESUMO
Objetivos: revisar a literatura sobre os aspectos clíni-cos, fisiopatológicos e terapêuticos da paralisia de Bell.Fonte de dados: revisão dos artigos indexados nas bases de dados Medline e Scielo. Os termos utilizados foram paralisia de Bell, epidemiologia, etiologia, Herpes simplex e tratamento.Síntese dos dados: alguns estudos demonstraram associação da paralisia de Bell com a infecção pelo vírus Herpes simplex. Fatores climáticos podem atuar como reativadores da infecção latente desse vírus no gânglio geniculado do nervo facial, causando o aparecimento da paralisia. O diagnóstico da paralisia de Bell é essencialmente clínico, afastando-se outras causas de paralisia facial periférica.Conclusões: a fisiopatologia da paralisia de Bell ainda permanece não bem esclarecida, embora tenha sido demonstrada associação com a presença do vírus Herpes simplex. O seu tratamento permanece controverso, no entanto recentes ensaios clínicos bem conduzidos confirmam o benefício dos corticosteróides.
Aims: To review the literature on clinical, physio-pathologic, and terapeutical aspects of Bell?s palsy.Source of data: A review of the articles indexed in Medline and Scielo databases. The terms used were Bell?s palsy, epidemiology, etiology, Herpes simplex, and treatment.Summary of the findings: Some studies have de-monstrated the association of Bell?s palsy with the Herpes simplex virus infection. Climatic factors have been studied as reactivators of the latent infection of that virus in the geniculate ganglion of the facial nerve, triggering the paralysis. The diagnosis of Bell?s palsy is essentially clinical, standing back other causes of peripheral facial palsy.Conclusions: The physiopathology of Bell?s palsy is still not completely understood, although the association with Herpes simplex virus has been demonstrated. The treatment remains controversial, nevertheless recent well designed clinical trials confirm the benefit of corticosteroids in the treatment of this condition.
