RESUMO
An elderly black man was admitted to our institution with macrocytic anemia, dysphagia, and significant weight loss. Results of an esophagogram were suggestive of achalasia. Gastric adenocarcinoma infiltrating the gastric cardia was seen on gastroscopy. The mode of presentation of gastric cancer in this case has not been previously reported in association with pernicious anemia. Patients with pernicious anemia are at higher risk of having gastrointestinal neoplasms than is the general population. We review the current literature and address the controversy concerning the need to subject patients with pernicious anemia to surveillance with upper gastrointestinal endoscopy.
Assuntos
Adenocarcinoma/diagnóstico , Anemia Perniciosa/diagnóstico , Acalasia Esofágica/diagnóstico , Neoplasias Gástricas/diagnóstico , Adenocarcinoma/complicações , Adenocarcinoma/diagnóstico por imagem , Idoso , Anemia Macrocítica/diagnóstico , Anemia Perniciosa/complicações , Cárdia/patologia , Transtornos de Deglutição/diagnóstico , Diagnóstico Diferencial , Acalasia Esofágica/diagnóstico por imagem , Gastroscopia , Humanos , Masculino , Radiografia , Fatores de Risco , Neoplasias Gástricas/complicações , Neoplasias Gástricas/diagnóstico por imagem , Redução de PesoRESUMO
Reported below is a case of eosinophilic gastro-enteritis involving the colon, stomach and duodenum in a patient who was also found to have marked hypoalbuminaemia and protein C deficiency due to severe protein-losing enteropathy. The most recent literature is reviewed and the challenging differential diagnosis of the disease is discussed.
Assuntos
Eosinofilia/complicações , Gastroenterite/complicações , Deficiência de Proteína C , Enteropatias Perdedoras de Proteínas/complicações , Diagnóstico Diferencial , Eosinofilia/diagnóstico , Eosinofilia/metabolismo , Gastroenterite/diagnóstico , Gastroenterite/metabolismo , Humanos , Masculino , Pessoa de Meia-Idade , Enteropatias Perdedoras de Proteínas/diagnóstico , Enteropatias Perdedoras de Proteínas/metabolismo , Albumina Sérica/deficiênciaRESUMO
A 74-year-old man had an isolated colonic ganglioneuroma presenting endoscopically as filiform polyposis coli. Extensive workup failed to show either von Recklinghausen's neurofibromatosis or multiple endocrine neoplasia (MEN) 2b. We discuss the clinical implications of this and review the literature.
