1.
ACS Comb Sci
; 13(5): 449-52, 2011 Sep 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21648463
RESUMO
The partnership between rational synthesis design and mass-triggered preparative LCMS is a powerful one, capable of furnishing very large libraries in a selective manner in a very short space of time. Herein, we communicate one example of possibly a perfect marriage between the synthetic chemistry and the subsequent purification method employed, affording a â¼1000-member library supplying 50 mg on average of final compound in less than a month.