[Comorbid status of patients with hypertension].

AIM: To establish age and gender characteristics, nosological structure of comorbidity among persons 20-99 years with hypertension. MATERIALS AND METHODS: The study is based on data from 21 514 electronic health records of the population (20-99 years old) with hypertension, mean age 63.0 years, 68.2% women. Diseases associated with hypertension with a frequency above 10% were analyzed. RESULTS: In the sample of people with hypertension, concomitant diseases were detected in 82.7% of cases, 1 disease accompanies 21.0% of the sample with hypertension, 2 diseases 17.9%, 3 diseases 14.0%, 4+ diseases 29.8%. The frequency of association of hypertension with ≥1 concomitant disease at the 20-29 years is 60.8% of cases, at 30-39 years - 65.1%, at 40-49 years - 73.9%, at 50-59 years - 81.1%, 60-69 years - 85.8%, 70-79 years - 87.3%, 80+ years - 86.2% of cases. Among women with hypertension, the average number of concomitant diseases is higher compared to men (3.47 vs 2.4 cases; p<0.001). Among young and middle-aged people, hypertension in most cases is associated with osteochondrosis, osteoarthritis, chronic pancreatitis, gastritis and duodenitis, retinal diseases, thyroid diseases, the female with hypertension accompanied by benign breast disease and menopausal disorders. Hypertension in the elderly is most often associated with cerebrovascular disease, coronary heart disease, diabetes mellitus, senile cataract, but osteochondrosis and osteoarthritis also do not lose their relevance. CONCLUSION: The existing system of organization of medical care cannot meet the needs of patients with comorbidity, which indicates the need to reorient medical care towards patient-centered care.

[Gender and age features frequencies of COVID-19].

The incidence of COVID-19, both complicated and uncomplicated pneumonia, among men is 40% higher than in women and increases at the age of 35-49 years, with a subsequent decrease in the rate. Pneumonia complicates the course of COVID-19 in older persons, due to the greater burden of comorbidity. Among men, the probability of contracting COVID-19 complicated by pneumonia is 1.4 times higher than among women. At the same time, the average duration of outpatient treatment among women is significantly higher both in the group of patients with COVID-19 with complicated and uncomplicated pneumonia. The data obtained indicate the need to develop additional measures to prevent the spread of COVID-19 infection among the male population and the middle-aged population, the incidence of the disease among which is the highest.