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1.
Ann Ig ; 34(4): 293-317, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-34652411

RESUMO

Background: We aimed to explore socioeconomic factors associated with obesity among adults and to investigate social inequality in obesity prevalence in Cyprus. Study design: Cross-sectional study. Methods: We conducted a survey among 3,021 Greek-Cypriots aged 25-64 years, collecting self-reported demographics, health behaviors, socioeconomic characteristics and anthropometric measurements. We performed univariable and multivariable (adjusting for demographics and health behaviors) sex-specific Poisson's regression with robust variance, reporting adjusted prevalence ratios (PRs) and 95% confidence intervals. Results: The prevalence of obesity was 22% among males and 17% among females. According to univariable analyses, higher obesity prevalence was associated with increased age, decreased physical activity and decreased alcohol consumption in both genders. In addition, obesity was associated with refugee status and former smoking in males and with a higher healthy diet score in females. There was a clear linear decrease in obesity prevalence each step up the socioeconomic hierarchy in both genders. In the fully adjusted model, a clear inverse gradient in obesity prevalence by educational attainment was observed in females (p=0.002), while, in males, lower obesity prevalence remained significantly associated with the highest level of family-net income and educational attainment (aPR:0.48; 95% CI:0.27-0.84 and aPR:0.46; 95% CI:0.25-0.84, respectively). Occupational social class was not associated with obesity. Conclusions: This study highlights striking social inequalities in obesity in an Eastern Mediterranean population, which only recently moved from rural living to high levels of development. We recommend that public health interventions should address education - and income-related barriers, as a means of tackling health inequalities.


Assuntos
Obesidade , Adulto , Estudos Transversais , Chipre/epidemiologia , Feminino , Inquéritos Epidemiológicos , Humanos , Masculino , Obesidade/epidemiologia , Prevalência , Fatores Socioeconômicos
2.
Clin Genet ; 93(3): 656-664, 2018 03.
Artigo em Inglês | MEDLINE | ID: mdl-29105741

RESUMO

Huntington disease (HD) is most prevalent among populations of western European descent and isolated populations where founder effects may operate. The aim of this study was to examine the epidemiology of HD in Cyprus, an island in southern Europe with extensive western European colonization in the past. All registered HD patients in the Cyprus, since 1994, were included. Detailed pedigrees and clinical information were recorded and maps, showing the geographic distribution of HD, were constructed. Requests for genetic testing were also examined. The project identified 58 clinically manifested cases of HD belonging to 19 families. The 16 families of Cypriot origin were concentrated in a confined geographical cluster in southeast Cyprus. In 2015, prevalence of symptomatic HD was 4.64/100 000 population, while incidence was 0.12/100 000 person-years. Prevalence displayed a marked increase during the past 20 years. Disease characteristics of HD patients were similar to those reported in western European populations. Lastly, the uptake of predictive and/or prenatal testing was limited. HD disease characteristics, incidence and prevalence in Cyprus were comparable to western European populations. Together with the geographical clustering observed, these results support the possibility for a relatively recent founder effect of HD in Cyprus, potentially of western European origin.


Assuntos
Doença de Huntington/epidemiologia , Idade de Início , Alelos , Chipre/epidemiologia , Feminino , Predisposição Genética para Doença , Genótipo , Geografia Médica , Humanos , Doença de Huntington/etiologia , Doença de Huntington/mortalidade , Incidência , Estimativa de Kaplan-Meier , Masculino , Vigilância da População , Prevalência , Prognóstico , Estudos Retrospectivos
3.
Heart Lung ; 28(4): 293-4, 1999.
Artigo em Inglês | MEDLINE | ID: mdl-10409316

RESUMO

Serratia Marcescens is a common, water-borne hospital colonizer. Respiratory secretions, wounds, and urine are frequently recognized areas of Serratia colonization. Serratia bacteremias usually occur nosocomially and are associated with high mortality and morbidity rates. Serratia bacteremias may be primary or secondary from an identifiable source. Hospital-acquired S marcescens bacteremias have no known source in half of the cases. We present a case of nosocomial primary S marcescens bacteremia in a surgical patient successfully treated with levofloxacin.


Assuntos
Anti-Infecciosos/uso terapêutico , Bacteriemia/tratamento farmacológico , Ponte de Artéria Coronária/efeitos adversos , Infecção Hospitalar/tratamento farmacológico , Endarterectomia das Carótidas/efeitos adversos , Levofloxacino , Ofloxacino/uso terapêutico , Infecções por Serratia/tratamento farmacológico , Serratia marcescens , Idoso , Idoso de 80 Anos ou mais , Bacteriemia/microbiologia , Infecção Hospitalar/microbiologia , Humanos , Masculino , Serratia marcescens/isolamento & purificação
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